Publication Beamlines Strategic Pillar
Pollock, Georgina L.; Grishin, Andrey M.; Giogha, Cristina; Gan, Jiyao; Oates, Clare V. et al. (2022). Targeting of microvillus protein Eps8 by the NleH effector kinases from enteropathogenic E. coli. Proceedings of the National Academy of Sciences of the United States of America 119(34) . 10.1073/pnas.2204332119. [PDB: 7tzk] CMCF-BM Health
Bullen, Nathan P.; Sychantha, David; Thang, Stephanie S.; Culviner, Peter H.; Rudzite, Marta et al. (2022). An ADP-ribosyltransferase toxin kills bacterial cells by modifying structured non-coding RNAs. Molecular Cell 82(18) , 3484-3498.e11. 10.1016/j.molcel.2022.08.015. CMCF-ID Health
Goedken, Eric R.; Argiriadi, Maria A.; Dietrich, Justin D.; Petros, Andrew M.; Krishnan, Navasona et al. (2022). Identification and structure-based drug design of cell-active inhibitors of interleukin 17A at a novel C-terminal site. Scientific Reports 12(1) . 10.1038/s41598-022-18760-1. [PDB: 8dyg] CMCF-ID Health
Kozlov, Guennadi; Mattijssen, Sandy; Jiang, Jianning; Nyandwi, Samuel; Sprules, Tara et al. (2022). Structural basis of 3′-end poly(A) RNA recognition by LARP1. Nucleic Acids Research 50(16) , 9534-9547. 10.1093/nar/gkac696. [PDB: 7soo, 7sop] CMCF-ID Health
Nguyen, Peter; Eshaque, Rony; Garland, Barbara Anne; Dang, Anthony; Suits, Michael D. L. et al. (2022). Degradation of chondroitin sulfate A by a PUL-like operon in Tannerella forsythia. PLoS ONE 17(9) , e0272904. 10.1371/journal.pone.0272904. [PDB: 8di0, 8di1] CMCF-BM, CMCF-ID Health
Taylor, Alexander M.; Bailey, Chris; Belmont, Lisa D.; Campbell, Robert; Cantone, Nico et al. (2022). GNE-064: A Potent, Selective, and Orally Bioavailable Chemical Probe for the Bromodomains of SMARCA2 and SMARCA4 and the Fifth Bromodomain of PBRM1. Journal of Medicinal Chemistry 65(16) , 11177-11186. 10.1021/acs.jmedchem.2c00662. [PDB: 7td9] CMCF-ID Health
Wilding, Birgit; Scharn, Dirk; Böse, Dietrich; Baum, Anke; Santoro, Valeria et al. (2022). Discovery of potent and selective HER2 inhibitors with efficacy against HER2 exon 20 insertion-driven tumors, which preserve wild-type EGFR signaling. Nature Cancer 3(7) , 821-836. 10.1038/s43018-022-00412-y. [PDB: 7pcd] CMCF-ID Health
Leontowich, Adam F. G.; Panahifar, Arash; Ostrowski, Ryan (2022). Fragmentation of hunting bullets observed with synchrotron radiation: Lighting up the source of a lesser-known lead exposure pathway. PLoS ONE 17(8) , e0271987. 10.1371/journal.pone.0271987. BMIT-ID, IDEAS Health
Guo, Amin; Zhang, Jianhua; He, Bo; Li, Angdi; Sun, Tianxiao et al. (2022). Quantitative, in situ visualization of intracellular insulin vesicles in pancreatic beta cells. Proceedings of the National Academy of Sciences of the United States of America 119(32) . 10.1073/pnas.2202695119. SM Health
Erika da Silva Sales (2022). The Spatio-Temporal Behavior of Basic Multicellular Units in a PTH-Induced Cortical Bone Remodeling Rabbit Model. Supervisor: Cooper, David. Saskatchewan, Canada: University of Saskatchewan. https://harvest.usask.ca/handle/10388/14105. BMIT-ID Health
Lee, J.; Kenward, C.; Worrall, L.J.; Vuckovic, M.; Paetzel, M. et al. (2022). Structure of SARS-CoV-2 Mpro in complex with nsp12-nsp13 (C12) cut site sequence. Protein Data Bank: 8ds1. CMCF-BM Health
Lee, J.; Kenward, C.; Worrall, L.J.; Vuckovic, M.; Paetzel, M. et al. (2022). Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp10-nsp11 (C10) cut site sequence (form 2). Protein Data Bank: 8drx. CMCF-BM Health
Lee, J.; Kenward, C.; Worrall, L.J.; Vuckovic, M.; Paetzel, M. et al. (2022). Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp7-nsp8 (C7) cut site sequence. Protein Data Bank: 8dru. CMCF-BM Health
Argiriadi, M.A.; Goedken, E.R. (2022). IL17A homodimer bound to Compound 7. Protein Data Bank: 8dyg. CMCF-ID Health
Bader, G. (2022). HER2 IN COMPLEX WITH A COVALENT INHIBITOR. Protein Data Bank: 7pcd. CMCF-ID Health