Publication Beamlines Strategic Pillar
Bryson, Steve; Thomson, Christy A.; Risnes, Louise F.; Dasgupta, Somnath; Smith, Kenneth et al. (2016). Structures of Preferred Human IgV Genes–Based Protective Antibodies Identify How Conserved Residues Contact Diverse Antigens and Assign Source of Specificity to CDR3 Loop Variation. Journal of Immunology 196(11) , 4723-4730. 10.4049/jimmunol.1402890. [PDB: 4hh9, 4hha] CMCF-ID Health
Blake, James F.; Burkard, Michael; Chan, Jocelyn; Chen, Huifen; Chou, Kang-Jye et al. (2016). Discovery of (S)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one (GDC-0994), an Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibitor in Early Clinical Development. Journal of Medicinal Chemistry 59(12) , 5650-5660. 10.1021/acs.jmedchem.6b00389. [PDB: 5k4i] CMCF-ID Health
Aydin, Halil; Sultana, Azmiri; Li, Sheng; Thavalingam, Annoj; Lee, Jeffrey E. et al. (2016). Molecular architecture of the human sperm IZUMO1 and egg JUNO fertilization complex. Nature 534(7608) , 562-565. 10.1038/nature18595. [PDB: 5f4e, 5f4t, 5f4v] CMCF-ID Health
Al-Dulaymi, Mays A.; Chitanda, Jackson M.; Mohammed-Saeid, Waleed; Araghi, Hessamaddin Younesi; Verrall, Ronald E. et al. (2016). Di-Peptide-Modified Gemini Surfactants as Gene Delivery Vectors: Exploring the Role of the Alkyl Tail in Their Physicochemical Behavior and Biological Activity. AAPS Journal 18(5) , 1168-1181. 10.1208/s12248-016-9906-1. Health
Ramaswamy; Raghavendran (2016). Structural characterization of TbFam50, TbPSSA2, and TCCISSA, surface proteins expressed by the trypanosome inside the tsetse vector. Supervisor: Boulanger, Martin. J. British Columbia, Canada: University of Victoria. http://hdl.handle.net/1828/7332. CMCF-BM, CMCF-ID Health
Ramaswamy; Raghavendran (2016). Structural characterization of TbFam50, TbPSSA2, and TCCISSA, surface proteins expressed by the trypanosome inside the tsetse vector. Supervisor: Boulanger, Martin. J. British Columbia, Canada: University of Victoria. http://hdl.handle.net/1828/7332. CMCF-BM, CMCF-ID Health
Whittington, D.A.; Epstein, L.F. (2016). B-Raf wild-type kinase domain in complex with a purinylpyridinylamino-based inhibitor. Protein Data Bank: 5fd2. CMCF-ID Health
Ulaganathan, T.S.; Shi, R.; Yao, D.; Garron, M.-L.; Cherney, M. et al. (2016). Heparinase III-BT4657 gene product. Protein Data Bank: 5jmf. CMCF-ID Health
Ulaganathan, T.S.; Shi, R.; Yao, D.; Garron, M.-L.; Cherney, M. et al. (2016). Heparinase III-BT4657 gene product, Methylated Lysines. Protein Data Bank: 5jmd. CMCF-ID Health
Sheriff, S. (2016). Structure of the extracellular domain of the CD40 in complex with 3H56-5 DAB. Protein Data Bank: 5dmj. CMCF-ID Health
Sheriff, S. (2016). Structure of the extracellular domain of the CD40 in complex with CHI220 FAB. Protein Data Bank: 5dmi. CMCF-ID Health
Sheriff, S. (2016). TGF-BETA RECEPTOR TYPE 1 KINASE DOMAIN (T204D,I211V,Y249F,S280T, Y282F,S287N,A350C,L352F). Protein Data Bank: 5e8u. CMCF-ID Health
Seattle Structural Genomics Center for Infectious Disease (SSGCID) (2016). Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline--tRNA ligase) from Plasmodium falciparum in complex with TCMDC-124506. Protein Data Bank: 4wi1. CMCF-ID Health
Scapin, G. (2016). Human DPP4 in complex with a novel tricyclic hetero-cycle inhibitor. Protein Data Bank: 5i7u. CMCF-ID Health
McTigue, M.; Deng, Y.-L.; Liu, W.; Brooun, A.; Stewart, A. et al. (2016). Structure of C1156Y Mutant Human Anaplastic Lymphoma Kinase in Complex with PF-06463922 ((10R)-7-amino-12-fluoro-2,10,16-trimethyl- 15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo(4,3-h)(2,5,11) benzoxadiazacyclotetradecine-3-carbonitrile).. Protein Data Bank: 5a9u. CMCF-ID Health