Publication Beamlines Strategic Pillar
McCallum, Matthew; Tammam, Stephanie; Khan, Ahmad; Burrows, Lori L.; Howell, P. Lynne et al. (2017). The molecular mechanism of the type IVa pilus motors. Nature Communications 8(1) . 10.1038/ncomms15091. [PDB: 5tsg, 5tsh] CMCF-ID Health
Yeung, Kap-Sun; Beno, Brett R.; Parcella, Kyle; Bender, John A.; Grant-Young, Katherine A. et al. (2017). Discovery of a Hepatitis C Virus NS5B Replicase Palm Site Allosteric Inhibitor (BMS-929075) Advanced to Phase 1 Clinical Studies. Journal of Medicinal Chemistry 60(10) , 4369-4385. 10.1021/acs.jmedchem.7b00328. [PDB: 5pzp] CMCF-ID Health
Tarry, Michael J.; Haque, Asfarul S.; Bui, Khanh Huy; Schmeing, T. Martin (2017). X-Ray Crystallography and Electron Microscopy of Cross- and Multi-Module Nonribosomal Peptide Synthetase Proteins Reveal a Flexible Architecture. Structure 25(5) , 783-793.e4. 10.1016/j.str.2017.03.014. [PDB: 5u89] CMCF-ID Health
Sakurada, Isao; Endo, Toshiya; Hikita, Katsuyoshi; Hirabayashi, Tomokazu; Hosaka, Yoshitaka et al. (2017). Discovery of novel aminobenzisoxazole derivatives as orally available factor IXa inhibitors. Bioorganic and Medicinal Chemistry Letters 27(11) , 2622-2628. 10.1016/j.bmcl.2017.03.002. [PDB: 5tnt] CMCF-ID Health
Fong, Desiree H.; Burk, David L.; Blanchet, Jonathan; Yan, Amy Y.; Berghuis, Albert M. et al. (2017). Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance. Structure 25(5) , 750-761. 10.1016/j.str.2017.03.007. [PDB: 5igh, 5igi, 5igj, 5igp, 5igr, 5igs, 5igt, 5igu, 5igv, 5igy, 5igz, 5ih0, 5ih1, 5iwu] CMCF-ID Health
Gorelik, Alexei; Liu, Fangyu; Illes, Katalin; Nagar, Bhushan (2017). Crystal structure of the human alkaline sphingomyelinase provides insights into substrate recognition. Journal of Biological Chemistry 292(17) , 7087-7094. 10.1074/jbc.m116.769273. [PDB: 5tcd, 5udy] CMCF-ID Health
El-Halfawy, Omar M.; Klett, Javier; Ingram, Rebecca J.; Loutet, Slade A.; Murphy, Michael E. P. et al. (2017). Antibiotic Capture by Bacterial Lipocalins Uncovers an Extracellular Mechanism of Intrinsic Antibiotic Resistance. mBio 8(2) , e00225-17. 10.1128/mbio.00225-17. [PDB: 5ixg, 5ixh] CMCF-ID Health
Curtin, Michael L.; Pliushchev, Marina A.; Li, Huan-Qiu; Torrent, Maricel; Dietrich, Justin D. et al. (2017). SAR of amino pyrrolidines as potent and novel protein-protein interaction inhibitors of the PRC2 complex through EED binding. Bioorganic and Medicinal Chemistry Letters 27(7) , 1576-1583. 10.1016/j.bmcl.2017.02.030. [PDB: 5u69, 5u6d] CMCF-ID Health
Alaverdashvili, Mariam; Hackett, Mark J.; Caine, Sally; Paterson, Phyllis G. (2017). Parallel changes in cortical neuron biochemistry and motor function in protein-energy malnourished adult rats. NeuroImage 149, 275-284. 10.1016/j.neuroimage.2017.02.010. MID-IR Health
Bailey-Elkin, B.A.; Mark, B.L. (2017). Crystal structure of the Middle East respiratory syndrome coronavirus papain-like protease bound to ubiquitin variant ME.2. Protein Data Bank: 5v6a. CMCF-BM Health
Beyrakhova, K.; Xu, C.; Boniecki, M.T.; Cygler, M. (2017). Structure of the effector protein SidK (lpg0968) from Legionella pneumophila. Protein Data Bank: 5ufk. CMCF-BM Health
Vadlamani, G.; Mark, B.L. (2017). Crystal structure of Burkholderia cenocepacia family 3 glycoside hydrolase (NagZ) bound to (3S,4R,5R,6S)-3-butyryl-4,5,6-trihydroxyazepane. Protein Data Bank: 5utr. CMCF-BM Health
Raczynska, J.E.; Shabalin, I.G.; Jaskolski, M.; Minor, W.; Wlodawer, A. et al. (2017). Crystal structure of NDM-1 in complex with beta-mercaptoethanol - new refinement. Protein Data Bank: 5n0i. CMCF-BM Health
Raczynska, J.E.; Shabalin, I.G.; Jaskolski, M.; Minor, W.; Wlodawer, A. et al. (2017). Crystal structure of NDM-1 in complex with hydrolyzed meropenem - new refinement. Protein Data Bank: 5n0h. CMCF-BM Health
Longenecker, K.L.; Raich, D.; Korepanova, A.V. (2017). Crystal structure of human NAMPT with A-1293201. Protein Data Bank: 5u2m. CMCF-ID Health