| Raheem, Izzat T.; Walji, Abbas M.; Klein, Daniel; Sanders, John M.; Powell, David A. et al. (2015). Discovery of 2-Pyridinone Aminals: A Prodrug Strategy to Advance a Second Generation of HIV-1 Integrase Strand Transfer Inhibitors. Journal of Medicinal Chemistry 58(20) , 8154-8165. 10.1021/acs.jmedchem.5b01037. [PDB: 4ztf] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Ndubaku, Chudi O.; Crawford, James J.; Drobnick, Joy; Aliagas, Ignacio; Campbell, David et al. (2015). Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-pKa Polar Moiety. ACS Medicinal Chemistry Letters 6(12) , 1241-1246. 10.1021/acsmedchemlett.5b00398. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Robb, Melissa; Robb, Craig S.; Higgins, Melanie A.; Hobbs, Joanne K.; Paton, James C. et al. (2015). A Second β-Hexosaminidase Encoded in the Streptococcus pneumoniae Genome Provides an Expanded Biochemical Ability to Degrade Host Glycans. Journal of Biological Chemistry 290(52) , 30888-30900. 10.1074/jbc.m115.688630. [PDB: 5a6a, 5a6b, 5a6k, 5ac5] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Baker, Perrin; Whitfield, Gregory B.; Hill, Preston J.; Little, Dustin J.; Pestrak, Matthew J. et al. (2015). Characterization of the Pseudomonas aeruginosa Glycoside Hydrolase PslG Reveals That Its Levels Are Critical for Psl Polysaccharide Biosynthesis and Biofilm Formation. Journal of Biological Chemistry 290(47) , 28374-28387. 10.1074/jbc.m115.674929. [PDB: 5bxa] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Gregg, Katie J.; Suits, Michael D.L.; Deng, Lehua; Vocadlo, David J.; Boraston, Alisdair B. et al. (2015). Structural Analysis of a Family 101 Glycoside Hydrolase in Complex with Carbohydrates Reveals Insights into Its Mechanism. Journal of Biological Chemistry 290(42) , 25657-25669. 10.1074/jbc.m115.680470. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Alaidi; Osama (2015). Structural characterization of Gemini-based nanoparticles for delivery of DNA. Supervisor: Grochulski, Pawel; Badea, Ildiko. Saskatchewan: University of Saskatchewan. http://hdl.handle.net/10388/ETD-2014-05-1619. |
CMCF-BM, CMCF-ID |
Masters Thesis |
Health |
| Alaidi; Osama (2015). Structural characterization of Gemini-based nanoparticles for delivery of DNA. Supervisor: Grochulski, Pawel; Badea, Ildiko. Saskatchewan: University of Saskatchewan. http://hdl.handle.net/10388/ETD-2014-05-1619. |
CMCF-BM, CMCF-ID |
Masters Thesis |
Health |
| Bergeret, F.; Argyropoulos, P.; Boddy, C.N.; Schmeing, T.M. (2015). Crystal structure of the thioesterase domain of deoxyerythronolide B synthase. Protein Data Bank: 5d3k. |
CMCF-BM |
PDB Deposition |
Health |
| Eigenbrot, C.; Yu, C. (2015). EGFR kinase (T790M/L858R) with inhibitor compound 15: ~{N}-(7-chloranyl-1~{H}-indazol-3-yl)-7,7-dimethyl-2-(1~{H}-pyrazol-4-yl)-5~{H}-furo[3,4-d]pyrimidin-4-amine. Protein Data Bank: 5edq. |
CMCF-BM |
PDB Deposition |
Health |
| Eigenbrot, C.; Yu, C. (2015). EGFR kinase (T790M/L858R) apo. Protein Data Bank: 5edp. |
CMCF-BM |
PDB Deposition |
Health |
| Whittington, D.A.; Tang, J.; Yakowec, P. (2015). Crystal structure of human PI3K-gamma in complex with benzimidazole inhibitor 5. Protein Data Bank: 5eds. |
CMCF-ID |
PDB Deposition |
Health |
| Parker, M.L.; Boulanger, M.J. (2015). Crystal structure of AMA4 DI-DII-EGF1 from Toxoplasma gondii. Protein Data Bank: 4z81. |
CMCF-ID |
PDB Deposition |
Health |
| Parker, M.L.; Boulanger, M.J. (2015). Crystal structure of Toxoplasma gondii AMA4 DI-DII-EGF1 in complex with a 33 aa TgRON2L1 peptide. Protein Data Bank: 4z80. |
CMCF-ID |
PDB Deposition |
Health |
| Sack, J.S. (2015). CRYSTAL STRUCTURE OF MICROTUBULE AFFINITY-REGULATING KINASE 4 CATALYTIC DOMAIN IN COMPLEX WITH A PYRAZOLOPYRIMIDINE INHIBITOR. Protein Data Bank: 5es1. |
CMCF-ID |
PDB Deposition |
Health |
| Bergeron, J.R.C.; Strynadka, N.C.J. (2015). crystal structure of the PscU C-terminal domain. Protein Data Bank: 5cul. |
CMCF-ID |
PDB Deposition |
Health |