Publication Beamlines Strategic Pillar
Watterson, Scott H.; De Lucca, George V.; Shi, Qing; Langevine, Charles M.; Liu, Qingjie et al. (2016). Discovery of 6-Fluoro-5-(R)-(3-(S)-(8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)-2-methylphenyl)-2-(S)-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1H-carbazole-8-carboxamide (BMS-986142): A Reversible Inhibitor of Bruton’s Tyrosine Kinase (BTK) Conformationally Constrained by Two Locked Atropisomers. Journal of Medicinal Chemistry 59(19) , 9173-9200. 10.1021/acs.jmedchem.6b01088. [PDB: 5t18] CMCF-ID Health
Wu, Yong-Jin; Guernon, Jason; Shi, Jianliang; Marcin, Lawrence; Higgins, Mendi et al. (2016). Discovery of S3-Truncated, C-6 Heteroaryl Substituted Aminothiazine β-Site APP Cleaving Enzyme-1 (BACE1) Inhibitors. Journal of Medicinal Chemistry 59(18) , 8593-8600. 10.1021/acs.jmedchem.6b01012. [PDB: 5kr8] CMCF-ID Health
Yamniuk, Aaron P.; Suri, Anish; Krystek, Stanley R.; Tamura, James; Ramamurthy, Vidhyashankar et al. (2016). Functional Antagonism of Human CD40 Achieved by Targeting a Unique Species-Specific Epitope. Journal of Molecular Biology 428(14) , 2860-2879. 10.1016/j.jmb.2016.05.014. [PDB: 5dmi, 5dmj] CMCF-ID Health
Almawi, Ahmad W.; Matthews, Lindsay A.; Larasati,; Myrox, Polina; Boulton, Stephen et al. (2016). ‘AND’ logic gates at work: Crystal structure of Rad53 bound to Dbf4 and Cdc7. Scientific Reports 6(1) . 10.1038/srep34237. [PDB: 5t2s] CMCF-BM Health
Gorelik, Alexei; Illes, Katalin; Heinz, Leonhard X.; Superti-Furga, Giulio; Nagar, Bhushan et al. (2016). Crystal structure of mammalian acid sphingomyelinase. Nature Communications 7(1) . 10.1038/ncomms12196. [PDB: 5fi9, 5fib, 5fic, 5hqn] CMCF-BM, CMCF-ID Health
Huang, Ji; Fraser, Marie E. (2016). Structural basis for the binding of succinate to succinyl-CoA synthetase. Acta Crystallographica Section D: Structural Biology 72(8) , 912-921. 10.1107/s2059798316010044. [PDB: 5cae] CMCF-BM Health
Smirnova, Ekaterina; Kwan, Jamie J.; Siu, Ryan; Gao, Xin; Zoidl, Georg et al. (2016). A new mode of SAM domain mediated oligomerization observed in the CASKIN2 neuronal scaffolding protein. Cell Communication and Signaling 14(1) , 17. 10.1186/s12964-016-0140-3. [PDB: 5l1m] CMCF-BM Health
Cooper, D. M. L.; Kawalilak, C. E.; Harrison, K.; Johnston, B. D.; Johnston, J. D. et al. (2016). Cortical Bone Porosity: What Is It, Why Is It Important, and How Can We Detect It?. Current Osteoporosis Reports 14(5) , 187-198. 10.1007/s11914-016-0319-y. BMIT-BM Health
Ambilwade; Dakshata (2016). Structural characterization of components of the flagellar export apparatus from the H. pylori. Supervisor: Moore, Stanley. Saskatchewan, Canada: University of Saskatchewan. http://hdl.handle.net/10388/7480. CMCF-BM, CMCF-ID Health
Ambilwade; Dakshata (2016). Structural characterization of components of the flagellar export apparatus from the H. pylori. Supervisor: Moore, Stanley. Saskatchewan, Canada: University of Saskatchewan. http://hdl.handle.net/10388/7480. CMCF-BM, CMCF-ID Health
Gorelik, A.; Illes, K.; Heinz, L.X.; Superti-Furga, G.; Nagar, B. et al. (2016). Catalytic domain of murine Acid Sphingomyelinase (ASMase, ASM, SMPD1). Protein Data Bank: 5hqn. CMCF-ID Health
Hughes, S.J.; Antoshchenko, T.; Mottaghi, K.; Barnard, L.; Strauss, E. et al. (2016). Staphylococcus aureus Type II pantothenate kinase in complex with a pantothenate analog. Protein Data Bank: 5jic. CMCF-ID Health
Kgosisejo, O.; Grochulski, P.; Tanaka, T. (2016). X-ray crystallography of recombinant Lactococcus lactis prolidase. Protein Data Bank: 4zng. CMCF-ID Health
Lewis, H.A.; Wu, Y.J.; Rajamani, R.; Thompson, L.A. (2016). (4~{S},6~{S})-4-[2,4-bis(fluoranyl)phenyl]-6-(3,5-dimethyl-1,2-oxazol-4-yl)-4-methyl-5,6-dihydro-1,3-thiazin-2-amine (compound 5) bound to BACE1. Protein Data Bank: 5kr8. CMCF-ID Health
Loewen, P.C. (2016). Crystal structure of the E198A variant of Burkholderia pseudomallei catalase-peroxidase KatG with INH. Protein Data Bank: 5sxx. CMCF-ID Health