| Elliott, J.Michael; Ultsch, Mark; Lee, Joshua; Tong, Raymond; Takeda, Kentaro et al. (2014). Antiparallel Conformation of Knob and Hole Aglycosylated Half-Antibody Homodimers Is Mediated by a CH2–CH3 Hydrophobic Interaction. Journal of Molecular Biology 426(9) , 1947-1957. 10.1016/j.jmb.2014.02.015. [PDB: 4nqt] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Johnson, Ted W.; Richardson, Paul F.; Bailey, Simon; Brooun, Alexei; Burke, Benjamin J. et al. (2014). Discovery of (10R)-7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a Macrocyclic Inhibitor of Anaplastic Lymphoma Kinase (ALK) and c-ros Oncogene 1 (ROS1) with Preclinical Brain Exposure and Broad-Spectrum Potency against ALK-Resistant Mutations. Journal of Medicinal Chemistry 57(11) , 4720-4744. 10.1021/jm500261q. [PDB: 4ctb] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Persch, Elke; Bryson, Steve; Todoroff, Nickolay K.; Eberle, Christian; Thelemann, Jonas et al. (2014). Binding to Large Enzyme Pockets: Small-Molecule Inhibitors of Trypanothione Reductase. ChemMedChem , 1880-1891. 10.1002/cmdc.201402032. [PDB: 4nev] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Higgins, Melanie A.; Suits, Michael D.; Marsters, Candace; Boraston, Alisdair B. (2014). Structural and Functional Analysis of Fucose-Processing Enzymes from Streptococcus pneumoniae. Journal of Molecular Biology 426(7) , 1469-1482. 10.1016/j.jmb.2013.12.006. [PDB: 4c21, 4c22] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Naftel, Steven J (2014). Elemental Distribution in Bone Impacted by Bacterial Diseases. Supervisor: Dr. Eldon Molto. Ontario, Canada: University of Western Ontario. https://ir.lib.uwo.ca/etd/1995. |
CLS-APS |
Masters Thesis |
Health |
| Jorgenson; Britta (2014). Cortical Porosity in Bone. Supervisor: Boyd, Steven. Alberta, Canada: University of Calgary. http://hdl.handle.net/11023/1516. |
BMIT-BM |
Masters Thesis |
Health |
| Min Xu; Mercedesz Balazs; Ning CHAI; Nancy Chiang; Henry Chiu et al. (2014). Anti-hemagglutinin antibodies and methods of use. Patent Number: WO2014078268A2. |
CMCF-ID |
Patent |
Health |
| Park, J.; Leung, C.Y.; Tsantrizos, Y.S.; Berghuis, A.M. (2014). Crystal structure of human FPPS in complex with CL03093. Protein Data Bank: 4lph. |
CMCF-ID |
PDB Deposition |
Health |
| Sridhar, V.; Badger, J.; Logan, C.; Chie-Leon, B.; NIenaber, V. et al. (2014). Crystal structure of PDE10A2 with fragment ZT0120 (7-chloroquinolin-4-ol). Protein Data Bank: 4mrw. |
CMCF-ID |
PDB Deposition |
Health |
| McTigue, M.A.; Deng, Y.L.; Liu, W.; Brooun, A.; Stewart, A.E. et al. (2014). Structure of the Human Anaplastic Lymphoma Kinase in Complex with the inhibitor (5R)-8-amino-3-fluoro-5,19-dimethyl-20-oxo-5,18,19,20- tetrahydro-7,11-(azeno)pyrido(2',1':2,3)imidazo(4,5-h)(2,5,11) benzoxadiazacyclotetradecine-14-carbonitrile. Protein Data Bank: 4ctb. |
CMCF-ID |
PDB Deposition |
Health |
| Oh, A.; Wang, W. (2014). Structural and Biochemical Analyses of the Catalysis and Potency Impact of Inhibitor Phosphoribosylation by Human Nicotinamide Phosphoribosyltransferase. Protein Data Bank: 4o0z. |
CMCF-ID |
PDB Deposition |
Health |
| Haji-Ghassemi, O.; Evans, S.V. (2014). Unliganded 3 crystal structure of S25-26 Fab. Protein Data Bank: 4ma1. |
CMCF-ID |
PDB Deposition |
Health |
| Blattner, C.; Wilson, I.A. (2014). Crystal structure of HIV-1 broadly neutralizing antibody PGT151. Protein Data Bank: 4nug. |
CMCF-ID |
PDB Deposition |
Health |
| Sridhar, V.; Badger, J.; Logan, C.; Chie-Leon, B.; Nienaber, V. et al. (2014). Crystal structure of PDE10A2 with fragment ZT1595 (2-[(quinolin-7-yloxy)methyl]quinoline). Protein Data Bank: 4msc. |
CMCF-ID |
PDB Deposition |
Health |
| Sridar, V.; Badger, J.; Logan, C.; Chie-Leon, B.; Nienaber, V. et al. (2014). Crystal structure of PDE10A2 with fragment ZT0449 (5-nitro-1H-benzimidazole). Protein Data Bank: 4msa. |
CMCF-ID |
PDB Deposition |
Health |