Publication Beamlines Strategic Pillar
Baral, Pravas Kumar; Swayampakula, Mridula; Aguzzi, Adriano; James, Michael N. G. (2018). Structural characterization of POM 6 Fab and mouse prion protein complex identifies key regions for prions conformational conversion. FEBS Journal 285(9) , 1701-1714. 10.1111/febs.14438. [PDB: 6aq7] CMCF-BM Health
Crowe, Adam M.; Workman, Sean D.; Watanabe, Nobuhiko; Worrall, Liam J.; Strynadka, Natalie C. J. et al. (2018). IpdAB, a virulence factor in Mycobacterium tuberculosis , is a cholesterol ring-cleaving hydrolase. Proceedings of the National Academy of Sciences of the United States of America 115(15) , E3378-E3387. 10.1073/pnas.1717015115. [PDB: 6co6, 6co9, 6coj, 6con] CMCF-BM Health
Pluvinage, Benjamin; Grondin, Julie M.; Amundsen, Carolyn; Klassen, Leeann; Moote, Paul E. et al. (2018). Molecular basis of an agarose metabolic pathway acquired by a human intestinal symbiont. Nature Communications 9(1) . 10.1038/s41467-018-03366-x. [PDB: 5t9a, 5t9x, 5ta0, 5ta1, 5ta5, 5ta7, 5ta9] CMCF-BM, CMCF-ID Health
Workman, Sean D.; Worrall, Liam J.; Strynadka, Natalie C. J. (2018). Crystal structure of an intramembranal phosphatase central to bacterial cell-wall peptidoglycan biosynthesis and lipid recycling. Nature Communications 9(1) . 10.1038/s41467-018-03547-8. [PDB: 6cb2] CMCF-ID Health
Zhang, Heng; Zhou, Bo; Qin, Su; Xu, Jing; Harding, Rachel et al. (2018). Structural and functional analysis of the DOT1L–AF10 complex reveals mechanistic insights into MLL-AF10-associated leukemogenesis. Genes & Development 32(5-6) , 341-346. 10.1101/gad.311639.118. [PDB: 6cko] CMCF-ID Health
Dementiev, Alexey; Silva, Abel; Yee, Calvin; Li, Zhe; Flavin, Michael T. et al. (2018). Structures of human plasma β–factor XIIa cocrystallized with potent inhibitors. Blood Advances 2(5) , 549-558. 10.1182/bloodadvances.2018016337. [PDB: 6b74] CMCF-ID Health
Reid, Joel W.; Kaduk, James A.; Matei, Lidia (2018). The crystal structure of MoO2(O2)H2O. Powder Diffraction 33(1) , 49-54. 10.1017/s0885715618000118. CMCF-BM Health
Wagner, Florence F.; Benajiba, Lina; Campbell, Arthur J.; Weïwer, Michel; Sacher, Joshua R. et al. (2018). Exploiting an Asp-Glu “switch” in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia. Science Translational Medicine 10(431) , eaam8460. 10.1126/scitranslmed.aam8460. [PDB: 5kpl, 5kpm] CMCF-ID Health
McAllister, Laura A.; Butler, Christopher R.; Mente, Scot; O’Neil, Steven V.; Fonseca, Kari R. et al. (2018). Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation. Journal of Medicinal Chemistry 61(7) , 3008-3026. 10.1021/acs.jmedchem.8b00070. [PDB: 6bq0] CMCF-ID Health
Kozlov, Guennadi; Wong, Kathy; Gehring, Kalle (2017). Crystal structure of the Legionella effector Lem22. Proteins: Structure. Function and Bioinformatics 86(2) , 263-267. 10.1002/prot.25427. [PDB: 5wd8] CMCF-ID Health
Xu, Chao; Liu, Ke; Lei, Ming; Yang, Ally; Li, Yanjun et al. (2018). DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants. Structure 26(1) , 85-95.e3. 10.1016/j.str.2017.11.022. [PDB: 5w9q] CMCF-ID Health
Yazdi, Aliakbar Khalili; Vezina, Grant C.; Shilton, Brian H. (2017). An alternate mode of oligomerization for E. coli SecA. Scientific Reports 7(1) . 10.1038/s41598-017-11648-5. [PDB: 5k9t] CMCF-ID Health
Beyrakhova, Ksenia A.; van Straaten, Karin; Li, Lei; Boniecki, Michal T.; Anderson, Deborah H. et al. (2016). Structural and Functional Investigations of the Effector Protein LpiR1 from Legionella pneumophila. Journal of Biological Chemistry 291(30) , 15767-15777. 10.1074/jbc.m115.708701. [PDB: 5fia, 5jg4] CMCF-ID Health
Zhang, Heng; Liu, Ke; Izumi, Natsuko; Huang, Haiming; Ding, Deqiang et al. (2017). Structural basis for arginine methylation-independent recognition of PIWIL1 by TDRD2. Proceedings of the National Academy of Sciences of the United States of America 114(47) , 12483-12488. 10.1073/pnas.1711486114. [PDB: 5j39] CMCF-ID Health
Stanger, Frédéric V.; de Beer, Tjaart A.P.; Dranow, David M.; Schirmer, Tilman; Phan, Isabelle et al. (2017). The BID Domain of Type IV Secretion Substrates Forms a Conserved Four-Helix Bundle Topped with a Hook. Structure 25(1) , 203-211. 10.1016/j.str.2016.10.010. [PDB: 4yk1] CMCF-ID Health