| Orita, T.; Doi, S.; Iwanaga, T.; Adachi, T. (2021). Crystal structure of human pyruvate dehydrogenase kinase 4 in complex with compound 2. Protein Data Bank: 7ebb. |
CMCF-ID |
PDB Deposition |
Health |
| Pham, N.T.H.; Calmettes, C.; Doucet, N. (2021). Crystal structure of G16S human Galectin-7 mutant in complex with lactose. Protein Data Bank: 6vts. |
CMCF-ID |
PDB Deposition |
Health |
| Pham, N.T.H.; Calmettes, C.; Doucet, N. (2021). Crystal structure of G16C human Galectin-7 mutant in complex with lactose. Protein Data Bank: 6vtq. |
CMCF-ID |
PDB Deposition |
Health |
| Sheriff, S. (2021). CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH BMS-986158, 2-{3-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-5-[(S)-(oxan-4-yl)(phenyl)methyl]-5H-pyrido[3,2-b]indol-7-yl}propan-2-ol. Protein Data Bank: 5s9r. |
CMCF-ID |
PDB Deposition |
Health |
| Sheriff, S. (2021). CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH 2-{(7P)-7-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-8-fluoro-5-[(S)-(oxan-4-yl)(phenyl)methyl]-5H-pyrido[3,2-b]indol-3-yl}propan-2-ol. Protein Data Bank: 7mce. |
CMCF-ID |
PDB Deposition |
Health |
| Workman, S.D.; Strynadka, N.C.J. (2021). Crystal structure of Bacillus subtilis UppS in complex with MAC-0547630. Protein Data Bank: 7jlm. |
CMCF-ID |
PDB Deposition |
Health |
| Workman, S.D.; Strynadka, N.C.J. (2021). Crystal structure of Bacillus subtilis UppS in complex with clomiphene. Protein Data Bank: 7jlj. |
CMCF-ID |
PDB Deposition |
Health |
| Workman, S.D.; Strynadka, N.C.J. (2021). Crystal structure of Bacillus subtilis UppS. Protein Data Bank: 7jli. |
CMCF-ID |
PDB Deposition |
Health |
| Workman, S.D.; Strynadka, N.C.J. (2021). Crystal structure of Bacillus subtilis UppS in complex with JPD447. Protein Data Bank: 7jlr. |
CMCF-ID |
PDB Deposition |
Health |
| Joan Seoane Suarez; Judit ANIDO FOLGUEIRA; Robin Matthew Hallett; Peter Edward BAYLISS; Ajitha JEGANATHAN et al. (2021). Methods for improving response to anti-lif antibody treatment in individuals with cancer. Patent Number: US20210253691A1. |
CMCF-ID |
Patent |
Health |
| Akaki, Tatsuo; Bessho, Yuki; Ito, Takashi; Fujioka, Shingo; Ubukata, Minoru et al. (2021). Fragment-based lead discovery to identify novel inhibitors that target the ATP binding site of pyruvate dehydrogenase kinases. Bioorganic and Medicinal Chemistry 44, 116283. 10.1016/j.bmc.2021.116283. [PDB: 7ebb] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Ereño-Orbea, June; Liu, Xianglei; Sicard, Taylor; Kucharska, Iga; Li, Wei et al. (2021). Structural details of monoclonal antibody m971 recognition of the membrane-proximal domain of CD22. Journal of Biological Chemistry 297(2) , 100966. 10.1016/j.jbc.2021.100966. [PDB: 7o4y, 7o52] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Gavai, Ashvinikumar V.; Norris, Derek; Delucca, George; Tortolani, David; Tokarski, John S. et al. (2021). Discovery and Preclinical Pharmacology of an Oral Bromodomain and Extra-Terminal (BET) Inhibitor Using Scaffold-Hopping and Structure-Guided Drug Design. Journal of Medicinal Chemistry 64(19) . 10.1021/acs.jmedchem.1c00625. [PDB: 5s9r] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Kumar, Amit; Paul, Marilyn; Panda, Manoranjan; Jayaram, Shruthi; Kalidindi, Narasimharaju et al. (2021). Molecular mechanism of interspecies differences in the binding affinity of TD139 to Galectin-3. Glycobiology 31(10) . 10.1093/glycob/cwab072. [PDB: 7cxa] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Rutbeek, Nicole R.; Rezasoltani, Hanieh; Patel, Trushar R.; Khajehpour, Mazdak; Prehna, Gerd et al. (2021). Molecular mechanism of quorum sensing inhibition in Streptococcus by the phage protein paratox. Journal of Biological Chemistry 297(3) , 100992. 10.1016/j.jbc.2021.100992. |
CMCF-ID |
Peer-Reviewed Article |
Health |