Publication Beamlines Strategic Pillar
Lu, J.; Patel, S.; Soisson, S. (2015). Crystal Structure of S.A. gyrase in complex with Compound 7. Protein Data Bank: 5bs3. CMCF-BM Health
Kwan, David H.; Constantinescu, Iren; Chapanian, Rafi; Higgins, Melanie A.; Kötzler, Miriam P et al. (2015). Toward Efficient Enzymes for the Generation of Universal Blood through Structure-Guided Directed Evolution. Journal of the American Chemical Society 137(17) , 5695-5705. 10.1021/ja5116088. [PDB: 4d6c, 4d6d, 4d6e, 4d6g] CMCF-BM, CMCF-ID Health
Hodge, Curtis D.; Edwards, Ross A.; Markin, Craig J.; McDonald, Darin; Pulvino, Mary et al. (2015). Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting. ACS Chemical Biology 10(7) , 1718-1728. 10.1021/acschembio.5b00222. [PDB: 4onm, 4onn] CMCF-BM Health
Hodge, C.D.; Edwards, R.A.; Glover, J.N.M. (2015). Crystal structure of human Mms2/Ubc13 - BAY 11-7082. Protein Data Bank: 4onn. CMCF-BM Health
Hodge, C.D.; Edwards, R.A.; Glover, J.N.M. (2015). Crystal structure of human Mms2/Ubc13 - NSC697923. Protein Data Bank: 4onm. CMCF-BM Health
Calmettes, C.; Moraes, T.F. (2015). Crystal structure of the isotype 1 Transferrin binding protein B (TbpB) from serogroup B Neisseria meningitidis. Protein Data Bank: 4qq1. CMCF-BM Health
Zamyatkin, D.F.; Parra, F.; Grochulski, P.; Ng, K.K.S. (2015). NV polymerase post-incorporation-like complex. Protein Data Bank: 4qpx. CMCF-ID Health
Tokarski, John S.; Zupa-Fernandez, Adriana; Tredup, Jeffrey A.; Pike, Kristen; Chang, ChiehYing et al. (2015). Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain. Journal of Biological Chemistry 290(17) , 11061-11074. 10.1074/jbc.m114.619502. [PDB: 4wov] CMCF-ID Health
Sivaprakasam, Prasanna; Han, Xiaojun; Civiello, Rita L.; Jacutin-Porte, Swanee; Kish, Kevin et al. (2015). Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core. Bioorganic and Medicinal Chemistry Letters 25(9) , 1856-1863. 10.1016/j.bmcl.2015.03.046. [PDB: 4ptc] CMCF-ID Health
Singh, Sheo B.; Kaelin, David E.; Wu, Jin; Miesel, Lynn; Tan, Christopher M. et al. (2015). Tricyclic 1,5-naphthyridinone oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents-SAR of left-hand-side moiety (Part-2). Bioorganic and Medicinal Chemistry Letters 25(9) , 1831-1835. 10.1016/j.bmcl.2015.03.044. [PDB: 5bs3] CMCF-ID Health
Setser, J.W.; Poy, F.; Tang, Y.; Bellon, S.F. (2015). Crystal structure of the first bromodomain of human BRD4 with benzotriazolo-diazepine scaffold. Protein Data Bank: 4z1s. CMCF-ID Health
Rao, D.E.C.S.; Li, Y.; He, Y.; Luo, Y. (2015). RadA from Methanococcus Voltae in complex with copper phthalocyanine tetrasulfonate inhibitor. Protein Data Bank: 4qkq. CMCF-ID Health
Pfoh, Roland; Lacdao, Ira Kay; Georges, Anna A.; Capar, Adam; Zheng, Hong et al. (2015). Crystal Structure of USP7 Ubiquitin-like Domains with an ICP0 Peptide Reveals a Novel Mechanism Used by Viral and Cellular Proteins to Target USP7. PLoS Pathogens 11(6) , e1004950. 10.1371/journal.ppat.1004950. [PDB: 4wpi] CMCF-ID Health
Pfoh, R.; Lacdao, I.K.L.; Saridakis, V. (2015). Crystal structure of USP7 ubiquitin-like domains in extended conformation. Protein Data Bank: 4wpi. CMCF-ID Health
Parker, Matthew J. (2015). Protein recognition of clinically-relevant carbohydrates. Supervisor: Evans, Stephen V.. British Columbia, Canada: University of Victoria. http://hdl.handle.net/1828/6264. CMCF-ID Health