Publication Beamlines Strategic Pillar
Kimani, S.; Dong, A.; Li, Y.; Seitova, A.; Al-awar, R. et al. (2024). Crystal structure of the human DCAF1 WDR domain in complex with OICR-41103. Protein Data Bank: 9d4e. CMCF-BM Health
Langelier, Marie-France; Mirhasan, Manija; Gilbert, Karine; Sverzhinksy, Aleksandr; Furtos, Alexandra et al. (2024). PARP enzyme de novo synthesis of protein-free poly(ADP-ribose). Molecular Cell 84(24) , 4758-4773.e6. 10.1016/j.molcel.2024.10.024. [PDB: 9bpy, 9dmc] CMCF-BM Health
Li, Hao; Agrawal, Sumit; Zhu, Ning; Cacciabue, Daniela I.; Rivolta, Marcelo N. et al. (2024). A novel therapeutic pathway to the human cochlear nerve. Scientific Reports 14(1) , 26795. 10.1038/s41598-024-74661-5. BMIT-ID Health
Mabanglo, Mark F.; Wilson, Brian; Noureldin, Mahmoud; Kimani, Serah W.; Mamai, Ahmed et al. (2024). Crystal structures of DCAF1-PROTAC-WDR5 ternary complexes provide insight into DCAF1 substrate specificity. Nature Communications 15(1) . 10.1038/s41467-024-54500-x. [PDB: 9b9h, 9b9t, 9b9w, 9ba2] CMCF-BM Health
Mabanglo, M.F.; Wilson, B.J.; Alvarez, H.G.; Hoffer, L.; Al-awar, R. et al. (2024). Crystal structure of the ternary complex of DCAF1 and WDR5 with PROTAC, OICR-40333. Protein Data Bank: 9b9h. CMCF-BM Health
Mabanglo, M.F.; Wilson, B.J.; Krausser, C.; Hoffer, L.; Al-awar, R. et al. (2024). Crystal structure of the ternary complex of DCAF1 and WDR5 with PROTAC, OICR-40407. Protein Data Bank: 9b9t. CMCF-BM Health
Mabanglo, M.F.; Wilson, B.J.; Mamai, A.; Hoffer, L.; Al-awar, R. et al. (2024). Crystal structure of the ternary complex of DCAF1 and WDR5 with PROTAC, OICR-40792. Protein Data Bank: 9b9w. CMCF-BM Health
Mabanglo, M.F.; Wilson, B.J.; Srivastava, S.; Al-awar, R.; Vedadi, M. et al. (2024). Crystal structure of the binary complex of DCAF1 and WDR5. Protein Data Bank: 9ba2. CMCF-BM Health
Muna, Tasneem Hassan; Rutbeek, Nicole R; Horne, Julia; Lao, Ying W; Krokhin, Oleg V et al. (2024). The phage protein paratox is a multifunctional metabolic regulator of Streptococcus. Nucleic Acids Research . 10.1093/nar/gkae1200. [PDB: 8vsq] CMCF-BM Health
Pistofidis, A.; Schmeing, T.M. (2024). The post-condensation state of the dimodular NRPS protein LgrA. Protein Data Bank: 9be4. CMCF-ID Health
Pistofidis, A.; Schmeing, T.M. (2024). The pre-condensation state of the dimodular NRPS protein LgrA. Protein Data Bank: 9be3. CMCF-ID Health
Poullennec, Karine G.; Jnoff, Eric; Abendroth, Jan; Bhuma, Naresh; Calmiano, Mark et al. (2024). Discovery of UCB9386: A Potent, Selective, and Brain-Penetrant Nuak1 Inhibitor Suitable for In Vivo Pharmacological Studies. Journal of Medicinal Chemistry 67(23) , 20879-20910. 10.1021/acs.jmedchem.4c01237. [PDB: 8uoj] CMCF-ID Health
Pushie, M Jake; Sylvain, Nicole J; Hou, Huishu; Pendleton, Nicole; Wang, Richard et al. (2024). X-ray fluorescence mapping of brain tissue reveals the profound extent of trace element dysregulation in stroke pathophysiology. Metallomics . 10.1093/mtomcs/mfae054. BIOXAS-IMAGING, IDEAS, MID-IR Health
Silva, M.; Dong, A.; Arrowsmith, C.H.; Edwards, A.M.; Halabelian, L. et al. (2024). Crystal Structure of SETDB1 Tudor domain in complex with UNC100016. Protein Data Bank: 9cux. CMCF-BM Health
Silva, M.; Dong, A.; Arrowsmith, C.H.; Edwards, A.M.; Halabelian, L. et al. (2024). Crystal Structure of SETDB1 Tudor domain in complex with UNC100013. Protein Data Bank: 9cuw. CMCF-BM Health