Publication Beamlines Strategic Pillar
Tokareva, Olena S.; Li, Kunhua; Travaline, Tara L.; Thomson, Ty M.; Swiecicki, Jean-Marie et al. (2023). Recognition and reprogramming of E3 ubiquitin ligase surfaces by α-helical peptides. Nature Communications 14(1) . 10.1038/s41467-023-42395-z. [PDB: 8ei4] CMCF-BM Health
Bailey-Elkin, Ben A.; Knaap, Robert C. M.; De Silva, Anuradha; Boekhoud, Ilse M.; Mous, Sandra et al. (2023). Demonstrating the importance of porcine reproductive and respiratory syndrome virus papain-like protease 2 deubiquitinating activity in viral replication by structure-guided mutagenesis. PLoS Pathogens 19(12) , e1011872. 10.1371/journal.ppat.1011872. [PDB: 8ehn] CMCF-ID Health
Cole, Andrew G.; Kultgen, Steven G.; Mani, Nagraj; Quintero, Jorge G.; Yi Fan, Kristi et al. (2023). Design, synthesis, and structure-activity relationship of a bicyclic HBV capsid assembly modulator chemotype leading to the identification of clinical candidate AB-506. Bioorganic and Medicinal Chemistry Letters 94, 129456. 10.1016/j.bmcl.2023.129456. [PDB: 8gbu] CMCF-ID Health
Kalliokoski, Tuomo; Kettunen, Henna; Kumpulainen, Esa; Kettunen, Emilia; Thieulin-Pardo, Gabriel et al. (2023). Discovery of novel methionine adenosyltransferase 2A (MAT2A) allosteric inhibitors by structure-based virtual screening. Bioorganic and Medicinal Chemistry Letters 94, 129450. 10.1016/j.bmcl.2023.129450. [PDB: 8p1t, 8p1v] CMCF-ID Health
Kattar, Solomon D.; Gulati, Anmol; Margrey, Kaila A.; Keylor, Mitchell H.; Ardolino, Michael et al. (2023). Discovery of MK-1468: A Potent, Kinome-Selective, Brain-Penetrant Amidoisoquinoline LRRK2 Inhibitor for the Potential Treatment of Parkinson’s Disease. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.3c01486. [PDB: 8six] CMCF-ID Health
Smith, Christopher R.; Chen, Dan; Christensen, James G.; Coulombe, René; Féthière, James et al. (2023). Discovery of Five SOS2 Fragment Hits with Binding Modes Determined by SOS2 X-Ray Cocrystallography. Journal of Medicinal Chemistry 67(1) , 774-781. 10.1021/acs.jmedchem.3c02140. [PDB: 8t5g, 8t5m, 8t5r] CMCF-BM, CMCF-ID Health
Thai, Elaine; Murugan, Rajagopal; Binter, Špela; Burn Aschner, Clare; Prieto, Katherine et al. (2023). Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein. Cell Reports 42(11) , 113330. 10.1016/j.celrep.2023.113330. [PDB: 8fb5] CMCF-ID Health
Varkaris, Andreas; Pazolli, Ermira; Gunaydin, Hakan; Wang, Qi; Pierce, Levi et al. (2023). Discovery and clinical proof-of-concept of RLY-2608, a first-in-class mutant-selective allosteric PI3Ka inhibitor that decouples anti-tumor activity from hyperinsulinemia. Cancer Discovery . 10.1158/2159-8290.cd-23-0944. [PDB: 8ts7] CMCF-ID Health
Rodriguez-Espinosa, Maria E.; Guevara-Oquendo, Victor H.; He, Jiangfeng; Zhang, Weixian; Yu, Peiqiang et al. (2023). Research updates and progress on nutritional significance of the amides I and II, alpha-helix and beta-sheet ratios, microbial protein synthesis, and steam pressure toasting condition with globar and synchrotron molecular microspectroscopic techniques with chemometrics. Critical Reviews in Food Science and Nutrition 65(2) , 367-381. 10.1080/10408398.2023.2274442. Health
Bakhshi, Nima (2023). Investigation of prepreg tack through development of an AFP simulator using in-situ sensing and physics-based simulation. Supervisor: Poursartip, Anoush; Vaziri, Reza. British Columbia, Canada: University of British Columbia. http://hdl.handle.net/2429/86974. BMIT-BM Materials
El Gamal, Islam Mohamed Medhat (2023). A Novel Metrology Standard for Synchrotron Produced Monochromatic X-ray Beams. Supervisor: McEwen, Malcolm R.. Ontario, Canada: Carleton University. https://repository.library.carleton.ca/concern/etds/mw22v685r?locale=en. BMIT-ID Materials
Michel J.R. Haché (2023). Synthesis and Characterization of Electrodeposited Nanocrystalline Medium- and High-Entropy Alloys. Supervisor: Erb, Uwe; Zou, Yu. Ontario, Canada: University of Toronto. https://www.proquest.com/docview/2889805979. BXDS-WHE Materials
Wu, Shuwen (2023). Investigation of Transition Metal-Based Catalysts for Electrochemical Energy Storage and Conversion. Supervisor: Cadien, Ken; Li, Zhi. Alberta, Canada: University of Alberta. https://doi.org/10.7939/r3-bm74-by37. HXMA Materials
Parzyck, Christopher Thomas (2023). SYNTHESIS, CHARACTERIZATION, AND SCATTERING MEASUREMENTS OF THE PEROVSKITE AND INFINITE-LAYER NICKELATES. Supervisor: Shen, Kyle. New York, USA: Cornell University. . REIXS Materials
Zhang, Bowen (2023). Investigations of Carbon Dioxide Electrolysis on Perovskite with Exsolved Nanoparticles in Solid Oxide Electrolysis Cell. Supervisor: Luo, Jing-Li; Zeng, Hongbo. Alberta, Canada: University of Alberta. https://doi.org/10.7939/r3-cned-1d53. VESPERS Materials