Publication Beamlines Strategic Pillar
Ketcham, John M.; Harwood, Stephen J.; Aranda, Ruth; Aloiau, Athenea N.; Bobek, Briana M. et al. (2024). Discovery of Pyridopyrimidinones that Selectively Inhibit the H1047R PI3Kα Mutant Protein. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c00078. [PDB: 8v8h] CMCF-ID Health
Li, Franco K. K.; Worrall, Liam J.; Gale, Robert T.; Brown, Eric D.; Strynadka, Natalie C. J. et al. (2024). Cryo-EM analysis of S. aureus TarL, a polymerase in wall teichoic acid biogenesis central to virulence and antibiotic resistance. Science Advances 10(9) . 10.1126/sciadv.adj3864. [PDB: 8v33] CMCF-ID Health
Perez-Bermejo, Juan A.; Efagene, Oghene; Matern, William M.; Holden, Jeffrey K.; Kabir, Shaheen et al. (2024). Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair. Nature Communications 15(1) . 10.1038/s41467-024-46816-5. [PDB: 8svg, 8svh, 8svi] CMCF-ID Health
Puumala, Emily; Sychantha, David; Lach, Elizabeth; Reeves, Shawn; Nabeela, Sunna et al. (2024). Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-β-thiophenylacrylamides exerts highly selective antifungal activity. Cell Chemical Biology . 10.1016/j.chembiol.2024.01.010. [PDB: 8uk6] CMCF-ID Health
Penner, Tiffany V.; Cobo, Neil Lorente; Patel, Deepak T.; Patel, Dhruvin H.; Savchenko, Alexei et al. (2023). Structural characterization of the Sel1‐like repeat protein LceB from Legionella pneumophila. Protein Science . 10.1002/pro.4889. [PDB: 8sxq] CMCF-BM Health
Petraccione, Kaylee; Ali, Mohamed G. H.; Cyr, Normand; Wahba, Haytham M.; Stocker, Timothy et al. (2024). An LIR motif in the Rift Valley fever virus NSs protein is critical for the interaction with LC3 family members and inhibition of autophagy. PLoS Pathogens 20(3) , e1012093. 10.1371/journal.ppat.1012093. [PDB: 8t2m] CMCF-BM Health
Shurtleff, Valerie W.; Layton, Mark E.; Parish, Craig A.; Perkins, James J.; Schreier, John D. et al. (2024). Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.3c02248. [PDB: 8ute] CMCF-BM Health
Daniel-Ivad, Phillip; Ryan, Katherine S. (2024). Structure of methyltransferase RedM that forms the dimethylpyrrolinium of the bisindole reductasporine. Journal of Biological Chemistry 300(1) , 105520. 10.1016/j.jbc.2023.105520. CMCF Health
Brown, Alyssa; Zhu, MengYu; Rohani, Alireza; Ladak, Hanif; Agrawal, Sumit K. et al. (2024). Surgical Considerations in Inner Ear Gene Therapy from Human Temporal Bone Anatomy. Laryngoscope 134(6) , 2879-2888. 10.1002/lary.31259. BMIT-ID Health
Loundagin, Lindsay L.; Harrison, Kim D.; Wei, Xuan; Cooper, David M.L. (2024). Understanding basic multicellular unit activity in cortical bone through 3D morphological analysis: New methods to define zones of the remodeling space. Bone 179, 116960. 10.1016/j.bone.2023.116960. BMIT-ID Health
Micuda, Ashley; Li, Hao; Rask‐Andersen, Helge; Ladak, Hanif M.; Agrawal, Sumit K. et al. (2024). Morphologic Analysis of the Scala Tympani Using Synchrotron: Implications for Cochlear Implantation. Laryngoscope . 10.1002/lary.31263. BMIT-ID Health
Liu, Yihong; Sun, Jiawei; McLeod, John A.; Deng, Ruoxin; Lee, Clement et al. (2024). Mn2+-Doped (Mg,Zn)Xgeoy Nanoparticles with Tunable, Excitation-Energy-Dependent Multi-Color Persistent Luminescence. Patent Number: 10.2139/ssrn.5042460. REIXS, SXRMB, VESPERS Materials
Liu, Xiaohui; Liu, Hao; Xia, Jie; Hu, Yongfeng; Shakouri, Mohsen et al. (2024). Bifunctional Moni4/Nickel Foam Electro-Catalyst for Ultra-Efficient Oxidation of High-Concentration 5-Hydroxymethylfurfural and Her. Patent Number: 10.2139/ssrn.4718489. SXRMB Materials
Liu, Yihong; Sun, Jiawei; McLeod, John A.; Deng, Ruoxin; Lee, Clement et al. (2024). Mn2+-Doped (Mg,Zn)Xgeoy Nanoparticles with Tunable, Excitation-Energy-Dependent Multi-Color Persistent Luminescence. Patent Number: 10.2139/ssrn.5042460. REIXS, SXRMB, VESPERS Materials
Liu, Yihong; Sun, Jiawei; McLeod, John A.; Deng, Ruoxin; Lee, Clement et al. (2024). Mn2+-Doped (Mg,Zn)Xgeoy Nanoparticles with Tunable, Excitation-Energy-Dependent Multi-Color Persistent Luminescence. Patent Number: 10.2139/ssrn.5042460. REIXS, SXRMB, VESPERS Materials