| Raman, Swetha; Beilschmidt, Melissa; To, Minh; Lin, Kevin; Lui, Francine et al. (2019). Structure-guided design fine-tunes pharmacokinetics, tolerability, and antitumor profile of multispecific frizzled antibodies. Proceedings of the National Academy of Sciences of the United States of America 116(14) , 6812-6817. 10.1073/pnas.1817246116. [PDB: 6o39, 6o3a] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Ryan, Patrick; Forrester, Taylor J.B.; Wroblewski, Charles; Kenney, Tristan M.G.; Kitova, Elena N. et al. (2019). The small RbcS-like domains of the β-carboxysome structural protein CcmM bind RubisCO at a site distinct from that binding the RbcS subunit. Journal of Biological Chemistry 294(8) , 2593-2603. 10.1074/jbc.ra118.006330. [PDB: 6mr1] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Sengupta, Shomit; Giaime, Emilie; Narayan, Sridhar; Hahm, Seung; Howell, Jessica et al. (2019). Discovery of NV-5138, the first selective Brain mTORC1 activator. Scientific Reports 9(1) , 4107. 10.1038/s41598-019-40693-5. [PDB: 6n0m] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Simonetta, Kyle R.; Taygerly, Joshua; Boyle, Kathleen; Basham, Stephen E.; Padovani, Chris et al. (2019). Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction. Nature Communications 10(1) , 1402. 10.1038/s41467-019-09358-9. [PDB: 6m91, 6m92, 6m93, 6m94] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Spergel, Steven H.; Mertzman, Michael E.; Kempson, James; Guo, Junqing; Stachura, Sylwia et al. (2019). Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis. ACS Medicinal Chemistry Letters 10(3) , 306-311. 10.1021/acsmedchemlett.8b00508. [PDB: 6ny4] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Wei, Yong; Xiong, Zi Jian; Li, Jun; Zou, Chunxia; Cairo, Christopher W. et al. (2019). Crystal structures of human lysosomal EPDR1 reveal homology with the superfamily of bacterial lipoprotein transporters. Communications Biology 2(1) . 10.1038/s42003-018-0262-9. [PDB: 6e7o] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| White, Brandy; Huh, Ian; Brooks, Cory L. (2019). Structure of a VHH isolated from a naïve phage display library. BMC Research Notes 12(1) . 10.1186/s13104-019-4197-0. [PDB: 6dyx] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Whitesell, Luke; Robbins, Nicole; Huang, David S.; McLellan, Catherine A.; Shekhar-Guturja, Tanvi et al. (2019). Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus. Nature Communications 10(1) , 402. 10.1038/s41467-018-08248-w. [PDB: 6cjl, 6cjp] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Brian E. CATHERS; Philip Chamberlain; Antonia Lopez-Girona; Gang Lu (2019). Compositions and methods for inducing conformational changes in cereblon and other e3 ubiquitin ligases. Patent Number: US20190017998. |
CMCF-ID |
Patent |
Health |
| Doyle, L.; Mallette, E.; Kimber, M.S. (2019). Escherichia coli KpsC, N-terminal domain. Protein Data Bank: 6mgc. |
CMCF-ID |
PDB Deposition |
Health |
| Evans, S.V.; Haji-Ghassemi, O. (2019). Unliganded S25-5 Fab. Protein Data Bank: 6c5i. |
CMCF-ID |
PDB Deposition |
Health |
| Evans, S.V.; Haji-Ghassemi, O. (2019). S25-5 Fab in complex with Chlamydiaceae-specific LPS antigen. Protein Data Bank: 6c5h. |
CMCF-ID |
PDB Deposition |
Health |
| Gytz, H.; Liang, J.; Liang, Y.; Gorelik, A.; Illes, K. et al. (2019). mouse beta-mannosidase bound to beta-D-mannose (MANBA). Protein Data Bank: 6ddu. |
CMCF-ID |
PDB Deposition |
Health |
| Gytz, H.; Liang, J.; Liang, Y.; Gorelik, A.; Illes, K. et al. (2019). mouse beta-mannosidase (MANBA). Protein Data Bank: 6ddt. |
CMCF-ID |
PDB Deposition |
Health |
| Haji-Ghassemi, O.; Evans, S.V. (2019). S25-23 Fab in complex with Chlamydiaceae LPS (Crystal form 2). Protein Data Bank: 6c5k. |
CMCF-ID |
PDB Deposition |
Health |