Ezekiel, Sean J.; Searle, Mackenzie; Park, Jaeok (2025). Engineering dimer mutants of human geranylgeranyl pyrophosphate synthase. PLoS ONE 20(1) , e0317437. 10.1371/journal.pone.0317437. [PDB: 9csl] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Ireland, Kendra A.; Kayrouz, Chase M.; Abbott, Marissa L.; Seyedsayamdost, Mohammad R.; Davis, Katherine M. et al. (2025). Structural and functional analysis of SAM-dependent N-methyltransferases involved in ovoselenol and ovothiol biosynthesis. Structure . 10.1016/j.str.2024.12.020. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Mendez, Alex; Bolling, Cydni; Taylor, Shane; Makumire, Stanley; Staker, Bart et al. (2025). Structure of Plasmodium vivax
N-myristoyltransferase with inhibitor IMP-1088: exploring an NMT inhibitor for antimalarial therapy. Acta Crystallographica Section F:Structural Biology Communications 81(1) , 1-10. 10.1107/s2053230x24011348. [PDB: 5v0w] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Whittington, D.A. (2025). Crystal structure of PRMT5:MEP50 in complex with MTA and oxamide compound 14. Protein Data Bank: 9n3o. |
CMCF-BM |
PDB Deposition |
Health |
Tran, N.; Holyoak, T. (2025). Crystal Structure of the Gemella haemolysans Immunoglobulin A1 Protease Trypsin-Like Domain. Protein Data Bank: 9ect. |
CMCF-BM |
PDB Deposition |
Health |
Kimani, S.; Dong, A.; Hoffmann, L.; Nemec, V.; Ackloo, S. et al. (2025). Crystal structure of the human WDR5 in complex with LH168 compound. Protein Data Bank: 9d5z. |
CMCF-BM |
PDB Deposition |
Health |
Langelier, M.F.; Pascal, J.M. (2025). Human PARP1 ART domain bound to NAD+ analog benzamide adenine dinucleotide and ADP-ribose. Protein Data Bank: 9dmc. |
CMCF-BM |
PDB Deposition |
Health |
Langelier, M.F.; Pascal, J.M. (2025). Human PARP1 ART domain bound to NAD+ analogs benzamide adenine dinucleotide and carba-NAD+. Protein Data Bank: 9bpy. |
CMCF-BM |
PDB Deposition |
Health |
Grainger, R.; Colussi, D.C.; Noble, M.; Junop, M.; Stathopulos, P.B. et al. (2025). Human mitochondrial calcium uniporter crystal structure (residues 74-165 resolved) with lithium. Protein Data Bank: 8urg. |
CMCF-BM |
PDB Deposition |
Health |
Rogers, C.M.; Langelaan, D.N. (2025). Crystal Structure of TREX1 Homolog Plex9.1 bound to ssDNA. Protein Data Bank: 9mrd. |
CMCF-BM |
PDB Deposition |
Health |
Stogios, P.J.; Whitesell, L.; Cowen, L.E.; Savchenko, A.; Joachimiak, A. et al. (2025). Crystal structure of Yck2 from Candida albicans in complex with inhibitor 2b: 6-fluoro-2-(4-fluorophenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyridine. Protein Data Bank: 9edy. |
CMCF-BM |
PDB Deposition |
Health |
Stogios, P.J.; Whitesell, L.; Cowen, L.E.; Savchenko, A.; Joachimiak, A. et al. (2025). Crystal structure of Yck2 from Candida albicans in complex with inhibitor 2a: 2-(4-fluorophenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyridine-6-carbonitrile. Protein Data Bank: 9edx. |
CMCF-BM |
PDB Deposition |
Health |
Stogios, P.J.; Whitesell, L.; Cowen, L.E.; Savchenko, A.; Joachimiak, A. et al. (2025). Crystal structure of Yck2 from Candida albicans in complex with inhibitor 1f: 7-fluoro-2-(4-fluorophenyl)-3-(pyridin-4-yl)imidazo[1,2-a]pyridine. Protein Data Bank: 9edw. |
CMCF-BM |
PDB Deposition |
Health |
Cottrell, Kevin M.; Briggs, Kimberly J.; Tsai, Alice; Tonini, Matthew R.; Whittington, Douglas A. et al. (2025). Discovery of TNG462: A Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitor to Target Cancers with MTAP Deletion. Journal of Medicinal Chemistry 68(5) , 5097-5119. 10.1021/acs.jmedchem.4c03067. [PDB: 9n3o] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Tran, Norman; Redzic, Jasmina S.; Eisenmesser, Elan Z.; Holyoak, Todd (2025). The structure of the Gemella haemolysans M26 IgA1 protease trypsin-like domain. Acta Crystallographica Section F:Structural Biology Communications 81(4) . 10.1107/s2053230x25001219. [PDB: 9ect] |
CMCF-BM |
Peer-Reviewed Article |
Health |