| Johnson, Ted W.; Richardson, Paul F.; Bailey, Simon; Brooun, Alexei; Burke, Benjamin J. et al. (2014). Discovery of (10R)-7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a Macrocyclic Inhibitor of Anaplastic Lymphoma Kinase (ALK) and c-ros Oncogene 1 (ROS1) with Preclinical Brain Exposure and Broad-Spectrum Potency against ALK-Resistant Mutations. Journal of Medicinal Chemistry 57(11) , 4720-4744. 10.1021/jm500261q. [PDB: 4ctb] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Lu, Jimmy (2025). Mechanistic Insights into Protease Function and Inhibition in Infectious Diseases. Supervisor: Lemieux, M. Joanne. Alberta, Canada: University of Alberta. https://doi.org/10.7939/83361. |
CMCF-BM |
Doctoral Thesis |
Health |
| Caveney, Nathanael Adam (2021). Structural insights into the modulation of bacterial peptidoglycan synthase activity. Supervisor: Strynadka, Natalie. British Columbia, Canada: University of British Columbia. http://hdl.handle.net/2429/75160. |
CMCF-BM |
Doctoral Thesis |
Health |
| Gerak, Chloe Ann Nolan (2020). Insights into the inhibition of ETV6 PNT domain polymerization. Supervisor: McIntosh, Lawrence; Roberge, Michel. British Columbia, Canada: University of British Columbia. http://hdl.handle.net/2429/75516. |
CMCF-BM |
Doctoral Thesis |
Health |
| Hedges, Jason (2024). Biochemical and structural studies of enzymes from the azomycin and beta-ethynylserine biosynthetic pathways. Supervisor: Ryan, Katherine S.. British Columbia, Canada: University of British Columbia. http://hdl.handle.net/2429/79048. |
CMCF-BM, CMCF-ID |
Doctoral Thesis |
Health |
| Nam, Sung-Eun (2012). Crystallographic analysis of Bacillus subtilis signal peptide peptidase (SppA). Supervisor: Paetzel, Mark; Harden, Nicolas; Young, Edgar. British Columbia, Canada: Simon Fraser University. https://summit.sfu.ca/item/13913. |
CMCF-BM |
Doctoral Thesis |
Health |
| Cho, Timothy HS (2024). Mechanisms of Sensory Signal Transduction Across the Envelope in the CpxRA System of Escherichia coli. Supervisor: Raivio, Tracy. Alberta, Canada: University of Alberta. https://doi.org/10.7939/r3-kpc4-mn64. |
CMCF-BM |
Doctoral Thesis |
Health |
| Sun, Luxin (2018). Involvement of BRCT Family Proteins in DNA Damage Response. Supervisor: Glover, Mark. Alberta, Canada: University of Alberta. https://doi.org/10.7939/R3CZ32K9V. |
CMCF-BM, CMCF-ID |
Doctoral Thesis |
Health |
| Torres, Miguel (2018). Structure and Function of Enzymes Involved With the Biosynthesis of Benzylisoquinoline Alkaloids. Supervisor: Ng, Kenneth Kai Sing. Alberta, Canada: University of Calgary. http://hdl.handle.net/1880/107653. |
CMCF-BM |
Doctoral Thesis |
Health |
| Ali, Mohamed (2023). Investigating the role of acetylation of LC3-family proteins in regulating autophagy. Supervisor: Omichinski, James G.. Quebec, Canada: Université de Montréal. http://hdl.handle.net/1866/32170. |
CMCF-BM |
Doctoral Thesis |
Health |
| Gorelik, Alexei (2018). Structural Study of the Acid Sphingomyelinase Protein Family. Supervisor: Nagar, Bhushan. QC, Canada: McGill University. https://escholarship.mcgill.ca/concern/theses/wp988n513. |
CMCF-BM, CMCF-ID |
Doctoral Thesis |
Health |
| Larasati, (2020). The characterization of Dbf4 interactions and roles in genome replication and stability in Saccharomyces cerevisiae. Supervisor: Duncker, Bernard. ON, Canada: University of Waterloo. http://hdl.handle.net/10012/15684. |
CMCF-BM |
Doctoral Thesis |
Health |
| Jones, Carys S. (2020). Structure, Function, and Inhibition of Peptidoglycan O-Acetyltransferase A from Staphylococcus aureus. Supervisor: Clarke, Anthony J. ON, Canada: University of Guelph. http://hdl.handle.net/10214/17946. |
CMCF-BM |
Doctoral Thesis |
Health |
| Itai Sharon (2022). Structural insights into the biosynthesis and biodegradation of cyanophycin. Supervisor: Schmeing, Thomas Martin. Quebec, Canada: McGill University. https://escholarship.mcgill.ca/concern/theses/5712md34f. |
CMCF-BM |
Doctoral Thesis |
Health |
| Tamura, Kazune (2021). Functional dissection of beta-glucan utilization by prominent human gut symbionts. Supervisor: Brumer, Harry. BC, Canada: University of British Columbia. http://hdl.handle.net/2429/77919. |
CMCF-BM |
Doctoral Thesis |
Health |