| Bagal, Sharan K.; Omoto, Kiyoyuki; Blakemore, David C.; Bungay, Peter J.; Bilsland, James G. et al. (2018). Discovery of Allosteric, Potent, Subtype Selective, and Peripherally Restricted TrkA Kinase Inhibitors. Journal of Medicinal Chemistry 62(1) , 247-265. 10.1021/acs.jmedchem.8b00280. [PDB: 6d20] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Bagal, Sharan K.; Andrews, Mark; Bechle, Bruce M.; Bian, Jianwei; Bilsland, James et al. (2018). Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of Pain. Journal of Medicinal Chemistry 61(15) , 6779-6800. 10.1021/acs.jmedchem.8b00633. [PDB: 6dkb] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Antonysamy, S. (2018). Structure of PRMT5:MEP50 in complex with LLY-283, a potent and selective inhibitor of PRMT5, with antitumor activity. Protein Data Bank: 6ckc. |
CMCF-ID |
PDB Deposition |
Health |
| Allingham, J.S.; Trofimova, D. (2018). Crystal structure of a curved tubulin complex induced by the kinesin-13 Kif2A. Protein Data Bank: 6bbn. |
CMCF-ID |
PDB Deposition |
Health |
| Alexander, J.A.N.; Strynadka, N.C.J. (2018). Crystal structure of wild-type S. aureus penicillin binding protein 4 (PBP4) in complex with nafcillin. Protein Data Bank: 5ty7. |
CMCF-ID |
PDB Deposition |
Health |
| Alexander, J.A.N.; Strynadka, N.C.J. (2018). Crystal structure of wild-type S. aureus penicillin binding protein 4 (PBP4) in complex with ceftobiprole. Protein Data Bank: 5txi. |
CMCF-ID |
PDB Deposition |
Health |
| Alexander, J.A.N.; Strynadka, N.C.J. (2018). Crystal structure of S. aureus penicillin binding protein 4 (PBP4) mutant (E183A, F241R) in complex with ceftobiprole. Protein Data Bank: 5tx9. |
CMCF-ID |
PDB Deposition |
Health |
| Alexander, J.A.N.; Strynadka, N.C.J. (2018). Crystal structure of wild-type S. aureus penicillin binding protein 4 (PBP4) in complex with ceftaroline. Protein Data Bank: 5tw8. |
CMCF-ID |
PDB Deposition |
Health |
| Alexander, J.A.N.; Strynadka, N.C.J. (2018). Crystal structure of S. aureus penicillin binding protein 4 (PBP4) mutant (E183A, F241R) in complex with ceftaroline. Protein Data Bank: 5tw4. |
CMCF-ID |
PDB Deposition |
Health |
| Verstraete; Meghan Marie (2018). SbnI is a free serine kinase and heme-sensing regulator required for staphyloferrin B biosynthesis in Staphylococcus aureus. Supervisor: Murphy, Michael. British Columbia, Canada: University of British Columbia. http://hdl.handle.net/2429/66404. |
CMCF-BM |
Doctoral Thesis |
Health |
| Moore, S.A.; Marshall, J.D.; Anderson, D.H. (2018). Structure of the Bovine p85alpha BH domain, R262T mutant. Protein Data Bank: 6d87. |
CMCF-BM |
PDB Deposition |
Health |
| Moore, S.A.; Marshall, J.D.; Anderson, D.H. (2018). Structure of the Bovine p85a BH domain. Protein Data Bank: 6d86. |
CMCF-BM |
PDB Deposition |
Health |
| Moore, S.A.; Marshall, J.D.; Anderson, D.H. (2018). Structure of the Bovine p85a BH domain E217K mutant. Protein Data Bank: 6d85. |
CMCF-BM |
PDB Deposition |
Health |
| Moore, S.A.; Marshall, J.D.; Anderson, D.H. (2018). Structure of the Bovine p85a BH domain. Protein Data Bank: 6d82. |
CMCF-BM |
PDB Deposition |
Health |
| Mellor, Paul; Marshall, Jeremy D. S.; Ruan, Xuan; Whitecross, Dielle E.; Ross, Rebecca L. et al. (2018). Patient-derived mutations within the N-terminal domains of p85α impact PTEN or Rab5 binding and regulation. Scientific Reports 8(1) . 10.1038/s41598-018-25487-5. [PDB: 6d81, 6d82, 6d85, 6d86, 6d87] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |