| Lei, M.; Tempel, W.; Arrowsmith, C.H.; Bountra, C.; Edwards, A.M. et al. (2019). MeCP2 MBD in complex with DNA. Protein Data Bank: 6ogj. |
CMCF-ID |
PDB Deposition |
Health |
| Fischmann, T.O. (2019). Murine PI3K delta kinsae domain - cpd 1. Protein Data Bank: 6mul. |
CMCF-ID |
PDB Deposition |
Health |
| Methot, Joey L.; Zhou, Hua; Kattar, Sam D.; McGowan, Meredeth A.; Wilson, Kevin et al. (2019). Structure Overhaul Affords a Potent Purine PI3Kδ Inhibitor with Improved Tolerability. Journal of Medicinal Chemistry 62(9) . 10.1021/acs.jmedchem.8b01818. [PDB: 6mul] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Guarne, A.; Almawi, A.W. (2019). Crystal structure of the Escherichia coli sliding clamp-MutL complex.. Protein Data Bank: 6e8e. |
CMCF-ID |
PDB Deposition |
Health |
| Doyle, Liam; Ovchinnikova, Olga G.; Myler, Katharine; Mallette, Evan; Huang, Bo-Shun et al. (2019). Biosynthesis of a conserved glycolipid anchor for Gram-negative bacterial capsules. Nature Chemical Biology 15(6) . 10.1038/s41589-019-0276-8. [PDB: 6mgb, 6mgc, 6mgd] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Caveney, Nathanael A.; Caballero, Guillermo; Voedts, Henri; Niciforovic, Ana; Worrall, Liam J. et al. (2019). Structural insight into YcbB-mediated beta-lactam resistance in Escherichia coli. Nature Communications 10(1) . 10.1038/s41467-019-09507-0. [PDB: 6ntz] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Almawi, Ahmad W; Scotland, Michelle K; Randall, Justin R; Liu, Linda; Martin, Heather K et al. (2019). Binding of the regulatory domain of MutL to the sliding β-clamp is species specific. Nucleic Acids Research 47(9) . 10.1093/nar/gkz115. [PDB: 6e8d, 6e8e] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Sengupta, Shomit; Giaime, Emilie; Narayan, Sridhar; Hahm, Seung; Howell, Jessica et al. (2019). Discovery of NV-5138, the first selective Brain mTORC1 activator. Scientific Reports 9(1) , 4107. 10.1038/s41598-019-40693-5. [PDB: 6n0m] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| O'Neill, D. (2019). CRYSTAL STRUCTURE OF SESTRIN2 IN COMPLEX WITH NV-0005138. Protein Data Bank: 6n0m. |
CMCF-ID |
PDB Deposition |
Health |
| Antoshchenko, T.; Chen, Y.; Hughes, S.; Park, H. (2019). Crystal structure of ATPase domain of Human GRP78 bound to Ver155008. Protein Data Bank: 6cz1. |
CMCF-ID |
PDB Deposition |
Health |
| Simonetta, Kyle R.; Taygerly, Joshua; Boyle, Kathleen; Basham, Stephen E.; Padovani, Chris et al. (2019). Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction. Nature Communications 10(1) , 1402. 10.1038/s41467-019-09358-9. [PDB: 6m91, 6m92, 6m93, 6m94] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Raman, S.; Beilschmidt, M.; Fransson, J.; Julien, J.P. (2019). Crystal structure of Frizzled 7 CRD in complex with F7.B Fab. Protein Data Bank: 6o3a. |
CMCF-ID |
PDB Deposition |
Health |
| Raman, S.; Beilschmidt, M.; Fransson, J.; Julien, J.P. (2019). Crystal structure of Frizzled 5 CRD in complex with F2.I Fab. Protein Data Bank: 6o39. |
CMCF-ID |
PDB Deposition |
Health |
| Raman, Swetha; Beilschmidt, Melissa; To, Minh; Lin, Kevin; Lui, Francine et al. (2019). Structure-guided design fine-tunes pharmacokinetics, tolerability, and antitumor profile of multispecific frizzled antibodies. Proceedings of the National Academy of Sciences of the United States of America 116(14) , 6812-6817. 10.1073/pnas.1817246116. [PDB: 6o39, 6o3a] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Li, T.; Lin, S.X. (2019). CRYSTAL STRUCTURE OF HUMAN 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 COMPLEXED WITH ESTRONE AND NADP+. Protein Data Bank: 6mne. |
CMCF-ID |
PDB Deposition |
Health |