Quiroz, Ryan V.; Reutershan, Michael H.; Schneider, Sebastian E.; Sloman, David; Lacey, Brian M. et al. (2021). The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer. Journal of Medicinal Chemistry 64(7) , 3911-3939. 10.1021/acs.jmedchem.0c02083. [PDB: 7kib] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Payandeh, J.; Ho, H. (2021). Fab CJ11 in complex IL-1beta peptide liberated by Caspase cleavage. Protein Data Bank: 7jwq. |
CMCF-ID |
PDB Deposition |
Health |
Murray, J.M. (2021). BRD4-BD1 Compound6 (methyl 4-(3,5-difluoropyridin-2-yl)-10-methyl-7-((methylsulfonyl)methyl)-11-oxo-3,4,10,11-tetrahydro-1H-1,4,10-triazadibenzo[cd,f]azulene-6-carboxylate). Protein Data Bank: 7khl. |
CMCF-ID |
PDB Deposition |
Health |
Mulligan, Vikram Khipple; Workman, Sean; Sun, Tianjun; Rettie, Stephen; Li, Xinting et al. (2021). Computationally designed peptide macrocycle inhibitors of New Delhi metallo-β-lactamase 1. Proceedings of the National Academy of Sciences of the United States of America 118(12) , e2012800118. 10.1073/pnas.2012800118. [PDB: 6xbe, 6xbf] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Majewski, Dorothy D.; Okon, Mark; Heinkel, Florian; Robb, Craig S.; Vuckovic, Marija et al. (2021). Characterization of the Pilotin-Secretin Complex from the Salmonella enterica Type III Secretion System Using Hybrid Structural Methods. Structure 29(2) . 10.1016/j.str.2020.08.006. [PDB: 6xfj] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
Majewski, Dorothy D.; Okon, Mark; Heinkel, Florian; Robb, Craig S.; Vuckovic, Marija et al. (2021). Characterization of the Pilotin-Secretin Complex from the Salmonella enterica Type III Secretion System Using Hybrid Structural Methods. Structure 29(2) . 10.1016/j.str.2020.08.006. [PDB: 6xfj] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
Lyons, B.; Lidster, T.; Merrill, A.R. (2021). Scabin (S117A) toxin from Streptomyces scabies. Protein Data Bank: 6vuv. |
CMCF-ID |
PDB Deposition |
Health |
Li, Z.; Rini, J.M. (2021). SARS-CoV-2 RBD in complex with Fab 15033. Protein Data Bank: 7klg. |
CMCF-BM |
PDB Deposition |
Health |
Li, Z.; Rini, J.M. (2021). SARS-CoV-2 RBD in complex with Fab 15033-7. Protein Data Bank: 7klh. |
CMCF-BM |
PDB Deposition |
Health |
Lin, C.S.; Chan, A.C.; Murphy, M.E. (2021). Crystal structure of the helical cell shape determining protein Pgp2 (K307A mutant) from Campylobacter jejuni. Protein Data Bank: 6xj7. |
CMCF-BM |
PDB Deposition |
Health |
Lin, Chang Sheng-Huei; Chan, Anson C.K.; Vermeulen, Jenny; Brockerman, Jacob; Soni, Arvind S. et al. (2021). Peptidoglycan binding by a pocket on the accessory NTF2-domain of Pgp2 directs helical cell shape of Campylobacter jejuni. Journal of Biological Chemistry 296, 100528. 10.1016/j.jbc.2021.100528. [PDB: 6xj7] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Li, Hao; Helpard, Luke; Ekeroot, Jonas; Rohani, Seyed Alireza; Zhu, Ning et al. (2021). Three-dimensional tonotopic mapping of the human cochlea based on synchrotron radiation phase-contrast imaging. Scientific Reports 11(1) , 4437. 10.1038/s41598-021-83225-w. |
BMIT-ID |
Peer-Reviewed Article |
Health |
Li, Chen; Zhang, Yuzhou; Zhu, Ning; Emady, Heather N.; Zhang, Lifeng et al. (2021). Experimental investigation of wet pharmaceutical granulation using in-situ synchrotron X-ray imaging. Powder Technology 378, 65-75. 10.1016/j.powtec.2020.09.063. |
BMIT-BM |
Peer-Reviewed Article |
Health |
Liang, J.; Naineni, S.K.; Pelletier, J.; Nagar, B. (2021). Crystal structure of eIF4A-I in complex with RNA bound to des-MePateA, a pateamine A analog. Protein Data Bank: 6xki. |
CMCF-ID |
PDB Deposition |
Health |
Langston, Steven P.; Grossman, Stephen; England, Dylan; Afroze, Roushan; Bence, Neil et al. (2021). Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer. Journal of Medicinal Chemistry 64(5) . 10.1021/acs.jmedchem.0c01491. [PDB: 6xog, 6xoh] |
CMCF-ID |
Peer-Reviewed Article |
Health |