| Puumala, Emily; Sychantha, David; Lach, Elizabeth; Reeves, Shawn; Nabeela, Sunna et al. (2024). Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-β-thiophenylacrylamides exerts highly selective antifungal activity. Cell Chemical Biology . 10.1016/j.chembiol.2024.01.010. [PDB: 8uk6] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Wang, F.; Cheng, W.; Lv, Z.; Ju, C.; Bao, C. et al. (2024). The Crystal Structure of USP8 from Biortus.. Protein Data Bank: 8y9a. |
CMCF-BM |
PDB Deposition |
Health |
| Krishnamurthy, H.; Zhuang, N.; Qiang, D.; Wu, Y.; Klein, D.J. et al. (2024). Structure of SARS-Cov2 3CLPro in complex with Compound 27. Protein Data Bank: 8ute. |
CMCF-BM |
PDB Deposition |
Health |
| Shurtleff, Valerie W.; Layton, Mark E.; Parish, Craig A.; Perkins, James J.; Schreier, John D. et al. (2024). Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.3c02248. [PDB: 8ute] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Folger, Ines B.; Frota, Natália F.; Pistofidis, Angelos; Niquille, David L.; Hansen, Douglas A. et al. (2024). High-throughput reprogramming of an NRPS condensation domain. Nature Chemical Biology . 10.1038/s41589-023-01532-x. [PDB: 8f7f] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| He, Liqi; Zhang, Meng Yao; Cox, Matthew; Zhang, Qian; Donnell, Andrew F. et al. (2024). Identification and Optimization of Small Molecule Pyrazolopyrimidine TLR7 Agonists for Applications in Immuno-oncology. ACS Medicinal Chemistry Letters 15(2) , 189-196. 10.1021/acsmedchemlett.3c00456. [PDB: 8s9h] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Boseley, Rhiannon E.; Sylvain, Nicole J.; Peeling, Lissa; Kelly, Michael E.; Pushie, M. Jake et al. (2024). A review of concepts and methods for FTIR imaging of biomarker changes in the post-stroke brain. Biochimica et Biophysica Acta - Biomembranes 1866(3) , 184287. 10.1016/j.bbamem.2024.184287. |
MID-IR |
Peer-Reviewed Article |
Health |
| Daniel-Ivad, Phillip (2024). Crystallographic and biochemical characterization of key steps in reductasporine and capuramycin biosynthesis. Supervisor: Ryan, Katherine S.. BC, Canada: University of British Columbia. http://hdl.handle.net/2429/87410. |
CMCF |
Doctoral Thesis |
Health |
| Dhindwal, P.; Ruzzini, A. (2024). Bile salt hydrolase from Arthrobacter citreus with covalent inhibitor AAA-10 bound. Protein Data Bank: 8vsy. |
CMCF-ID |
PDB Deposition |
Health |
| Ruzzini, A.; Dhindwal, P. (2024). Bile salt hydrolase from Arthrobacter citreus. Protein Data Bank: 8vrx. |
CMCF-ID |
PDB Deposition |
Health |
| Tomlinson, A.C.A.; Chen, A.; Knox, J.E.; Yano, J.K. (2024). Tricomplex of RMC-7977, KRAS G12C, and CypA. Protein Data Bank: 8tbk. |
CMCF-ID |
PDB Deposition |
Health |
| Tomlinson, A.C.A.; Chen, A.; Knox, J.E.; Yano, J.K. (2024). Tricomplex of RMC-7977, KRAS G12A, and CypA. Protein Data Bank: 8tbj. |
CMCF-ID |
PDB Deposition |
Health |
| Tomlinson, A.C.A.; Chen, A.; Knox, J.E.; Yano, J.K. (2024). Tricomplex of RMC-7977, NRAS WT, and CypA. Protein Data Bank: 8tbi. |
CMCF-ID |
PDB Deposition |
Health |
| Bar Ziv, T.; Zhang, D.; Tomlinson, A.C.A.; Knox, J.E.; Yano, J.K. et al. (2024). Tricomplex of RMC-7977, KRAS G12R, and CypA. Protein Data Bank: 8tbh. |
CMCF-ID |
PDB Deposition |
Health |
| Chen, A.; Tomlinson, A.C.A.; Knox, J.E.; Yano, J.K. (2024). Tricomplex of RMC-7977, HRAS WT, and CypA. Protein Data Bank: 8tbg. |
CMCF-ID |
PDB Deposition |
Health |