| Afroz, Sharmin; Brownlie, Robert; Fodje, Michel; van Drunen Littel-van den Hurk, Sylvia (2019). The bovine herpesvirus-1 major tegument protein, VP8, interacts with host HSP60 concomitant with deregulation of mitochondrial function. Virus Research 261, 37-49. 10.1016/j.virusres.2018.12.006. |
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Peer-Reviewed Article |
Health |
| Liu, Yanli; Qin, Su; Chen, Tsai-Yu; Lei, Ming; Dhar, Shilpa S. et al. (2019). Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4. Nature Communications 10(1) . 10.1038/s41467-018-07906-3. [PDB: 6mlc] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Spergel, Steven H.; Mertzman, Michael E.; Kempson, James; Guo, Junqing; Stachura, Sylwia et al. (2019). Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis. ACS Medicinal Chemistry Letters 10(3) , 306-311. 10.1021/acsmedchemlett.8b00508. [PDB: 6ny4] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Almawi, Ahmad W; Scotland, Michelle K; Randall, Justin R; Liu, Linda; Martin, Heather K et al. (2019). Binding of the regulatory domain of MutL to the sliding β-clamp is species specific. Nucleic Acids Research 47(9) . 10.1093/nar/gkz115. [PDB: 6e8d, 6e8e] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Sengupta, Shomit; Giaime, Emilie; Narayan, Sridhar; Hahm, Seung; Howell, Jessica et al. (2019). Discovery of NV-5138, the first selective Brain mTORC1 activator. Scientific Reports 9(1) , 4107. 10.1038/s41598-019-40693-5. [PDB: 6n0m] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Simonetta, Kyle R.; Taygerly, Joshua; Boyle, Kathleen; Basham, Stephen E.; Padovani, Chris et al. (2019). Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction. Nature Communications 10(1) , 1402. 10.1038/s41467-019-09358-9. [PDB: 6m91, 6m92, 6m93, 6m94] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Raman, Swetha; Beilschmidt, Melissa; To, Minh; Lin, Kevin; Lui, Francine et al. (2019). Structure-guided design fine-tunes pharmacokinetics, tolerability, and antitumor profile of multispecific frizzled antibodies. Proceedings of the National Academy of Sciences of the United States of America 116(14) , 6812-6817. 10.1073/pnas.1817246116. [PDB: 6o39, 6o3a] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Doyle, L.; Mallette, E.; Kimber, M.S. (2019). Escherichia coli KpsC, N-terminal domain. Protein Data Bank: 6mgc. |
CMCF-ID |
PDB Deposition |
Health |
| Hitchcock, Adam P.; Wang, Xiaoyue; Grandfield, Kathryn; Everett, James; Collingwood, Joanna F. et al. (2019). Correlative Spectromicroscopy and Tomography for Biomedical Applications Involving Electron, Ion, and Soft X-ray Microscopies. Microscopy Today 27(2) , 12-19. 10.1017/s1551929518001256. |
SM |
Peer-Reviewed Article |
Health |
| Caveney, N.A.; Strynadka, N.C.J.; Caballero, G.; Worrall, L.J. (2019). Crystal structure of E. coli PBP5-meropenem. Protein Data Bank: 6ntz. |
CMCF-BM |
PDB Deposition |
Health |
| Kiefer, J.R.; Vinogradova, M.; Liang, J.; Zhang, B.; Ortwine, D.F. et al. (2019). Crystal structure of estrogen receptor alpha in complex with receptor degrader 16aa. Protein Data Bank: 6dfn. |
CMCF-ID |
PDB Deposition |
Health |
| Moss, D.L.; Park, H.W.; Mettu, R.R.; Landry, S.J. (2019). Pseudomonas exotoxin A domain III T18H477L. Protein Data Bank: 6edg. |
CMCF-ID |
PDB Deposition |
Health |
| Wei, Yong; Xiong, Zi Jian; Li, Jun; Zou, Chunxia; Cairo, Christopher W. et al. (2019). Crystal structures of human lysosomal EPDR1 reveal homology with the superfamily of bacterial lipoprotein transporters. Communications Biology 2(1) . 10.1038/s42003-018-0262-9. [PDB: 6e7o] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Nation, C.; Pizarro, J.C. (2019). Candida albicans Hsp90 nucleotide binding domain in complex with radicicol. Protein Data Bank: 6cjp. |
CMCF-ID |
PDB Deposition |
Health |
| Nation, C.; Pizarro, J.C. (2019). Candida albicans Hsp90 nucleotide binding domain in complex with radicicol. Protein Data Bank: 6cjl. |
CMCF-ID |
PDB Deposition |
Health |