Publication Beamlines Strategic Pillar
Saran, Anshu; Kim, Hey-Min; Manning, Ireland; Hancock, Mark A; Schmitz, Claus et al. (2024). Unveiling the molecular mechanisms of the type IX secretion system's response regulator: Structural and functional insights. PNAS Nexus 3(8) . 10.1093/pnasnexus/pgae316. [PDB: 8ted] CMCF-BM Health
Sauvé, Véronique; Stefan, Eric; Croteau, Nathalie; Goiran, Thomas; Fakih, Rayan et al. (2024). Activation of parkin by a molecular glue. Nature Communications 15(1) . 10.1038/s41467-024-51889-3. [PDB: 8w31] CMCF-ID Health
Ireland, Kendra A.; Kayrouz, Chase M.; Abbott, Marissa L.; Seyedsayamdost, Mohammad R.; Davis, Katherine M. et al. (2024). Structural insights into the convergent evolution of sulfoxide synthase EgtB-IV, an ergothioneine-biosynthetic homolog of ovothiol synthase OvoA. Structure . 10.1016/j.str.2024.08.006. [PDB: 8vig, 8vih] CMCF-ID Health
Hsiao, Yi-Chun; Wallweber, Heidi Ackerly; Alberstein, Robert G.; Lin, Zhonghua; Du, Changchun et al. (2024). Rapid affinity optimization of an anti-TREM2 clinical lead antibody by cross-lineage immune repertoire mining. Nature Communications 15(1) . 10.1038/s41467-024-52442-y. [PDB: 8t59] CMCF-ID Health
Golisch, Benedikt; Cordeiro, Rosa Lorizolla; Fraser, Alexander S.C.; Briggs, Jonathon; Stewart, William A. et al. (2024). The molecular basis of cereal mixed-linkage β-glucan utilization by the human gut bacterium Segatella copri. Journal of Biological Chemistry 300(9) , 107625. 10.1016/j.jbc.2024.107625. [PDB: 9bal, 9bmk] CMCF-ID Health
Farahinia, Alireza; Khani, Milad; Morhart, Tyler A.; Wells, Garth; Badea, Ildiko et al. (2024). A Novel Size-Based Centrifugal Microfluidic Design to Enrich and Magnetically Isolate Circulating Tumor Cells from Blood Cells through Biocompatible Magnetite–Arginine Nanoparticles. Sensors 24(18) , 6031. 10.3390/s24186031. SYLMAND Health
Mabanglo, M.F.; Houry, W.A. (2024). Crystal structure of Neisseria meningitidis ClpP protease in complex with phosphine oxide compound ACP6-12. Protein Data Bank: 8szn. CMCF-BM Health
Mabanglo, M.F.; Houry, W.A. (2024). Crystal structure of E. coli ClpP protease in complex with phosphine oxide compound ACP6-12. Protein Data Bank: 8szm. CMCF-BM Health
Lin, Funing; Mabanglo, Mark F.; Zhou, Jin Lin; Binepal, Gursonika; Barghash, Marim M. et al. (2024). Structure-Based Design and Development of Phosphine Oxides as a Novel Chemotype for Antibiotics that Dysregulate Bacterial ClpP Proteases. Journal of Medicinal Chemistry 67(17) , 15131-15147. 10.1021/acs.jmedchem.4c00773. [PDB: 8szm, 8szn] CMCF-BM Health
Cygler, M.; Boniecki, M.T. (2024). Structure of human Cysteine desulfurase Nfs1 with L-propargylglycine bound to active site PLP in complex with ISD11, Acp1 and ISCU2. Protein Data Bank: 8tvt. CMCF-ID Health
Trofimova, D.; Doubleday, C.; Hunter, B.; Serrano Arevalo, J.; Davison, E. et al. (2024). Crystal structure of the Candida albicans kinesin-8 proximal tail domain. Protein Data Bank: 9crw. CMCF-ID Health
Zimmermann, Elizabeth A.; DeVet, Taylor; Cilla, Myriam; Albiol, Laia; Kavaseri, Kyle et al. (2024). Tissue material properties, whole-bone morphology and mechanical behavior in the Fbn1C1041G/+ mouse model of Marfan syndrome. Matrix Biology Plus 23, 100155. 10.1016/j.mbplus.2024.100155. BMIT-BM Health
Zheng, X.; Ji, N.; Campbell, V.; Slavin, A.; Zhu, X. et al. (2024). Crystal structure of CRBN with compound 3. Protein Data Bank: 9cuo. CMCF-ID Health
Zheng, Xiaozhang; Ji, Nan; Campbell, Veronica; Slavin, Anthony; Zhu, Xiao et al. (2024). Discovery of KT-474─a Potent, Selective, and Orally Bioavailable IRAK4 Degrader for the Treatment of Autoimmune Diseases. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c01305. [PDB: 9cuo] CMCF-ID Health
Burke, J.E.; Barlow-Busch, I. (2024). Structure of PIK3CA with covalent inhibitor ALO26. Protein Data Bank: 8twy. CMCF-ID Health