Publication Beamlines Strategic Pillar
Higgins, Melanie A.; Suits, Michael D.; Marsters, Candace; Boraston, Alisdair B. (2014). Structural and Functional Analysis of Fucose-Processing Enzymes from Streptococcus pneumoniae. Journal of Molecular Biology 426(7) , 1469-1482. 10.1016/j.jmb.2013.12.006. [PDB: 4c21, 4c22] CMCF-BM Health
Johnson, Ted W.; Richardson, Paul F.; Bailey, Simon; Brooun, Alexei; Burke, Benjamin J. et al. (2014). Discovery of (10R)-7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a Macrocyclic Inhibitor of Anaplastic Lymphoma Kinase (ALK) and c-ros Oncogene 1 (ROS1) with Preclinical Brain Exposure and Broad-Spectrum Potency against ALK-Resistant Mutations. Journal of Medicinal Chemistry 57(11) , 4720-4744. 10.1021/jm500261q. [PDB: 4ctb] CMCF-ID Health
Loewen, Peter C.; Carpena, Xavi; Vidossich, Pietro; Fita, Ignacio; Rovira, Carme et al. (2014). An Ionizable Active-Site Tryptophan Imparts Catalase Activity to a Peroxidase Core. Journal of the American Chemical Society 136(20) , 7249-7252. 10.1021/ja502794e. [PDB: 5syh, 5syk] CMCF-ID Health
Oh, Angela; Ho, Yen-Ching; Zak, Mark; Liu, Yongbo; Chen, Xukun et al. (2014). Structural and Biochemical Analyses of the Catalysis and Potency Impact of Inhibitor Phosphoribosylation by Human Nicotinamide Phosphoribosyltransferase. ChemBioChem 15(8) , 1121-1130. 10.1002/cbic.201402023. [PDB: 4o0z, 4o10] CMCF-ID Health
Persch, Elke; Bryson, Steve; Todoroff, Nickolay K.; Eberle, Christian; Thelemann, Jonas et al. (2014). Binding to Large Enzyme Pockets: Small-Molecule Inhibitors of Trypanothione Reductase. ChemMedChem , 1880-1891. 10.1002/cmdc.201402032. [PDB: 4nev] CMCF-BM Health
Recht, Michael I.; Sridhar, Vandana; Badger, John; Bounaud, Pierre-Yves; Logan, Cheyenne et al. (2014). Identification and Optimization of PDE10A Inhibitors Using Fragment-Based Screening by Nanocalorimetry and X-ray Crystallography. Journal of Biomolecular Screening 19(4) , 497-507. 10.1177/1087057113516493. [PDB: 4mrw, 4mrz, 4ms0, 4msa, 4msc, 4mse] CMCF-ID Health
Tonkin, Michelle L.; Beck, Josh R.; Bradley, Peter J.; Boulanger, Martin J. (2014). The Inner Membrane Complex Sub-compartment Proteins Critical for Replication of the Apicomplexan Parasite Toxoplasma gondii Adopt a Pleckstrin Homology Fold. Journal of Biological Chemistry 289(20) , 13962-13973. 10.1074/jbc.m114.548891. CMCF-ID Health
Wyrzucki, Arkadiusz; Dreyfus, Cyrille; Kohler, Ines; Steck, Marco; Wilson, Ian A. et al. (2014). Alternative Recognition of the Conserved Stem Epitope in Influenza A Virus Hemagglutinin by a V H 3-30-Encoded Heterosubtypic Antibody. Journal of Virology 88(12) , 7083-7092. 10.1128/jvi.00178-14. [PDB: 4py8] CMCF-ID Health
Aluri, Esther Rani; Hayes, John R.; Walker, James D. S.; Grosvenor, Andrew P. (2014). Investigation of the Structural Stability of Ion-Implanted Gd2Ti2–xSnxO7 Pyrochlore-Type Oxides by Glancing Angle X-ray Absorption Spectroscopy. Journal of Physical Chemistry C 118(15) , 7910-7922. 10.1021/jp4095497. CLS-APS, SXRMB Materials
Anderson, Danielle L.; Mirzayans, Razmik; Andrais, Bonnie; Siegbahn, E. Albert; Fallone, B. Gino et al. (2014). Spatial and temporal distribution of γH2AX fluorescence in human cell cultures following synchrotron-generated X-ray microbeams: lack of correlation between persistent γH2AX foci and apoptosis. Journal of Synchrotron Radiation 21(4) , 801-810. 10.1107/s1600577514011424. BMIT-BM Materials
Bassey, Bassey; Moreno, Beatriz; Gomez, Ariel; Ahmed, Asm Sabbir; Ullrich, Doug et al. (2014). Synchrotron radiation shielding design for the Brockhouse sector at the Canadian light source. Radiation Physics and Chemistry 98, 109-112. 10.1016/j.radphyschem.2014.01.011. Materials
Chen, Chunmei; Dynes, James J.; Wang, Jian; Karunakaran, Chithra; Sparks, Donald L. et al. (2014). Soft X-ray Spectromicroscopy Study of Mineral-Organic Matter Associations in Pasture Soil Clay Fractions. Environmental Science and Technology 48(12) , 140604083949004. 10.1021/es405485a. SM Materials
de Jong, Mathijs; Meijerink, Andries; Gordon, Robert A.; Barandiarán, Zoila; Seijo, Luis et al. (2014). Is Bi2+Responsible for the Red-Orange Emission of Bismuth-Doped SrB4O7?. Journal of Physical Chemistry C 118(18) , 9696-9705. 10.1021/jp502996t. CLS-APS Materials
Fodje, Michel; Grochulski, Pawel; Janzen, Kathryn; Labiuk, Shaunivan; Gorin, James et al. (2014). 08B1-1: an automated beamline for macromolecular crystallography experiments at the Canadian Light Source. Journal of Synchrotron Radiation 21(3) , 633-637. 10.1107/s1600577514005578. CMCF-BM Materials
Iyer, Ganjigunte R. Swathi; Wang, Jian; Wells, Garth; Guruvenket, Srinivasan; Payne, Scott et al. (2014). Large-Area, Freestanding, Single-Layer Graphene–Gold: A Hybrid Plasmonic Nanostructure. ACS Nano 8(6) , 6353-6362. 10.1021/nn501864h. MID-IR, SM, SYLMAND Materials