Publication Beamlines Strategic Pillar
Throner, Scott; Feng, Tianshu; Andersen, Jannik N.; Bandi, Madhavi; Engel, Justin L. et al. (2025). Discovery of TNG-6132, a potent, selective, and orally bioavailable USP1 inhibitor. Bioorganic and Medicinal Chemistry Letters 124, 130262. 10.1016/j.bmcl.2025.130262. [PDB: 9n9y] CMCF-BM Health
Fraser, Bryan J.; Young, Nicholas J.; Bender, Brian J.; Gahbauer, Stefan; Ilyassov, Olzhas et al. (2025). Large Library Docking and Biophysical Analysis of Small-Molecule TMPRSS2 Inhibitors. Journal of Medicinal Chemistry 68(19) , 19893-19907. 10.1021/acs.jmedchem.4c03089. CMCF-ID Health
Kimani, Serah W.; Noureldin, Mahmoud; Wilson, Brian; Hoffer, Laurent; Green, Stuart R. et al. (2025). OICR-41103 as a chemical probe for the DCAF1 WD40 domain. Communications Biology 8(1) . 10.1038/s42003-025-08491-0. [PDB: 9yv4] CMCF-ID Health
Hemmings, Mark; Zieliński, Michał; Golkar, Tolou; Blanchet, Jonathan; Pistofidis, Angelos et al. (2025). Enzyme-mediated aminoglycoside resistance without target mimicry. Communications Chemistry 8(1) . 10.1038/s42004-025-01666-0. [PDB: 9mgu] CMCF-ID Health
Abdoli, Amirabbas; Yang, Zhihan; Odeh‐Ahmed, Abdullah; Bednova, Olga; Lemieux, Bruno et al. (2025). Probing the extent of importin‐α targeting of the TAF8 NLS by eliminating its cationic net‐charge. Protein Science 34(9) . 10.1002/pro.70272. [PDB: 9cl8, 9cle, 9clf, 9clg] CMCF-ID Health
Bian, Zhiguo; Schmidt, Robert G.; Wilson, Noel S.; Duignan, David B.; Breinlinger, Eric et al. (2025). Discovery of Orally Efficacious Bridged Piperazines as smTNF Modulators. Journal of Medicinal Chemistry 68(14) , 14357-14383. 10.1021/acs.jmedchem.5c00323. [PDB: 9ojs, 9ok6] CMCF-ID Health
Weller, Caroline; Burnett, G. Leslie; Jiang, Lingyan; Chakraborty, Sujata; Zhang, Dongyu et al. (2025). A neomorphic protein interface catalyzes covalent inhibition of RAS G12D aspartic acid in tumors. Science 389(6758) . 10.1126/science.ads0239. [PDB: 9ct7, 9ct9, 9cta, 9ctb] CMCF-ID Health
Petzold, Georg; Gainza, Pablo; Annunziato, Stefano; Lamberto, Ilaria; Trenh, Peter et al. (2025). Mining the CRBN target space redefines rules for molecular glue–induced neosubstrate recognition. Science 389(6755) . 10.1126/science.adt6736. [PDB: 9nfr] CMCF-ID Health
Hu, Tianhao; Billinghurst, Brant; Zhao, Jianbao; Liu, Bowen; Chen, Ziqiu et al. (2025). The Synchrotron-based Far-infrared Spectrum of Propargylamine. Astrophysical Journal. Supplement Series 280(1) , 41. 10.3847/1538-4365/adf95d. FAR-IR Environment
Zhi, Songsong; Zou, Xiaoxiao; Yang, Can; Wu, Dapeng; Guo, Hong et al. (2025). D-orbital regulation triggers energy recovery for simultaneous photocatalytic heavy metal reduction and H2O2 production. Applied Catalysis B: Environmental 371, 125215. 10.1016/j.apcatb.2025.125215. HXMA, SXRMB Environment
Hao, Xiaoge; Dong, Zhi Liang; Ma, Jiabin; Li, Weihan; Fu, Jiamin et al. (2025). A Universal Solid Reaction Enabling Nanosized Li 2 S in an Amorphous Matrix for All-Solid-State Li–S Batteries. Journal of the American Chemical Society . 10.1021/jacs.4c18340. BXDS-WHE, HXMA, SXRMB Materials
Xu, Jiabin; Wang, Jingsong; Sheng, Xinyue; Ding, Hui; Xu, Jun et al. (2025). Unlocking Water Adsorption Mechanisms in Y-BTC MOF: Insights from XAFS and SSNMR Spectroscopy. Journal of Physical Chemistry C 129(38) , 17341-17352. 10.1021/acs.jpcc.5c05403. BXDS-WHE, HXMA, SGM Materials
Coello-Mauleón, César; Ramos-Castillo, Carlos M.; Arredondo-Espínola, Alejandro; Álvarez-Contreras, Lorena; Guerra-Balcázar, Minerva et al. (2025). Single-Atom Catalyst with Optimized Ni Content in a Flexible Zn-Air Battery Operated at a Wide Temperature Range. ACS Applied Materials and Interfaces . 10.1021/acsami.5c13455. HXMA Materials
Wu, Yuwei; Huang, Guohe; Zhao, Kai; Yin, Jianan; Zhang, Peng et al. (2025). Innovative Co-Doped MXene and Aerogel Catalysts for Rapid and Efficient Degradation of Carbamazepine via PMS Activation and Singlet Oxygen Generation. Journal of Environmental Chemical Engineering , 119388. 10.1016/j.jece.2025.119388. HXMA, VESPERS Environment
Wu, Mingjie; Yang, Siyi; Gao, Yang; Chen, Zhangsen; Dong, Fang et al. (2025). Steering CO2 Electroreduction Pathway via Tuning Microenvironment of Cobalt Center in Molecular Catalysts. ACS Nano . 10.1021/acsnano.5c09554. HXMA Materials