Publication Beamlines Strategic Pillar
Riggs, Jennifer R.; Elsner, Jan; Cashion, Dan; Robinson, Dale; Tehrani, Lida et al. (2019). Design and Optimization Leading to an Orally Active TTK Protein Kinase Inhibitor with Robust Single Agent Efficacy. Journal of Medicinal Chemistry 62(9) , 4401-4410. 10.1021/acs.jmedchem.8b01869. [PDB: 6n6o] CMCF-ID Health
Tamura, Kazune; Foley, Matthew H.; Gardill, Bernd R.; Dejean, Guillaume; Schnizlein, Matthew et al. (2019). Surface glycan-binding proteins are essential for cereal beta-glucan utilization by the human gut symbiont Bacteroides ovatus. Cellular and Molecular Life Sciences 76(21) . 10.1007/s00018-019-03115-3. [PDB: 6e9b] CMCF-BM Health
Ishizawa, Jo; Zarabi, Sarah F.; Davis, R. Eric; Halgas, Ondrej; Nii, Takenobu et al. (2019). Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality. Cancer Cell 35(5) . 10.1016/j.ccell.2019.03.014. [PDB: 6dl7] CMCF-ID Health
Methot, Joey L.; Zhou, Hua; Kattar, Sam D.; McGowan, Meredeth A.; Wilson, Kevin et al. (2019). Structure Overhaul Affords a Potent Purine PI3Kδ Inhibitor with Improved Tolerability. Journal of Medicinal Chemistry 62(9) . 10.1021/acs.jmedchem.8b01818. [PDB: 6mul] CMCF-ID Health
Doyle, Liam; Ovchinnikova, Olga G.; Myler, Katharine; Mallette, Evan; Huang, Bo-Shun et al. (2019). Biosynthesis of a conserved glycolipid anchor for Gram-negative bacterial capsules. Nature Chemical Biology 15(6) . 10.1038/s41589-019-0276-8. [PDB: 6mgb, 6mgc, 6mgd] CMCF-BM, CMCF-ID Health
Caveney, Nathanael A.; Caballero, Guillermo; Voedts, Henri; Niciforovic, Ana; Worrall, Liam J. et al. (2019). Structural insight into YcbB-mediated beta-lactam resistance in Escherichia coli. Nature Communications 10(1) . 10.1038/s41467-019-09507-0. [PDB: 6ntz] CMCF-BM, CMCF-ID Health
Li, Hao; Schart-Morén, Nadine; Rohani, Seyed Alireza; Ladak, Hanif M.; Rask-Andersen, Helge et al. (2019). Synchrotron Radiation-Based Reconstruction of the Human Spiral Ganglion: Implications for Cochlear Implantation. Ear and Hearing 41(1) , 173–181. 10.1097/aud.0000000000000738. BMIT-ID Health
Li, Tang; Stephen, Preyesh; Zhu, Dao‐Wei; Shi, Rong; Lin, Sheng‐Xiang et al. (2019). Crystal structures of human 17β‐hydroxysteroid dehydrogenase type 1 complexed with estrone andNADP+reveal the mechanism of substrate inhibition. FEBS Journal 286(11) . 10.1111/febs.14784. [PDB: 6mne] CMCF-BM, CMCF-ID Health
Mangat, Chand S.; Vadlamani, Grishma; Holicek, Viktor; Chu, Mitchell; Larmour, Veronica L. C. et al. (2019). Molecular Basis for the Potent Inhibition of the Emerging Carbapenemase VCC-1 by Avibactam. Antimicrobial Agents and Chemotherapy 63(4) . 10.1128/aac.02112-18. [PDB: 6mk6] CMCF-BM, CMCF-ID Health
Zhang, Birong; Kiefer, James R.; Blake, Robert A.; Chang, Jae H.; Hartman, Steven et al. (2019). Unexpected equivalent potency of a constrained chromene enantiomeric pair rationalized by co-crystal structures in complex with estrogen receptor alpha. Bioorganic and Medicinal Chemistry Letters 29(7) . 10.1016/j.bmcl.2019.01.036. [PDB: 6dfn] CMCF-ID Health
Vyavhare, Kimaya; Bagi, Sujay; Patel, Mihir; Aswath, Pranesh B. (2019). Impact of Diesel Engine Oil Additives–Soot Interactions on Physiochemical, Oxidation, and Wear Characteristics of Soot. Energy and Fuels 33(5) , 4515-4530. 10.1021/acs.energyfuels.8b03841. SGM, SXRMB, VLS-PGM Environment
Marhaba, Iman; Ferry, Daniel; Laffon, Carine; Regier, Thomas Z.; Ouf, François-Xavier et al. (2019). Aircraft and MiniCAST soot at the nanoscale. Combustion and Flame 204, 278-289. 10.1016/j.combustflame.2019.03.018. SGM Environment
Izawa, Matthew R. M.; Dynes, James J.; Banerjee, Neil R.; Flemming, Roberta L.; MacLean, Lachlan C. W. et al. (2019). Organic Matter Preservation and Incipient Mineralization of Microtubules in 120 Ma Basaltic Glass. Frontiers in Earth Science 7. 10.3389/feart.2019.00149. SM Environment
Skierszkan, Elliott K.; Robertson, Jared M.; Lindsay, Matthew B. J.; Stockwell, Justin S.; Dockrey, John W. et al. (2019). Tracing Molybdenum Attenuation in Mining Environments Using Molybdenum Stable Isotopes. Environmental Science and Technology 53(10) , 5678-5686. 10.1021/acs.est.9b00766. HXMA Environment
Xin, Xiaying; Huang, Gordon; An, Chunjiang; Weger, Harold; Cheng, Guanhui et al. (2019). Analyzing the Biochemical Alteration of Green Algae During Chronic Exposure to Triclosan Based on Synchrotron-Based Fourier Transform Infrared Spectromicroscopy. Analytical Chemistry 91(12) . 10.1021/acs.analchem.9b01417. MID-IR Environment