Publication Beamlines Strategic Pillar
Kiefer, J.R.; Vinogradova, M. (2016). Structure of histone lysine demethylase KDM5A in complex with selective inhibitor. Protein Data Bank: 5ceh. CMCF-ID Health
Sheriff, S. (2016). TGF-BETA RECEPTOR TYPE 1 KINASE DOMAIN (T204D,I211V,Y249F,S280T, Y282F,S287N,A350C,L352F). Protein Data Bank: 5e8u. CMCF-ID Health
Whittington, D.A.; Epstein, L.F. (2016). B-Raf wild-type kinase domain in complex with a purinylpyridinylamino-based inhibitor. Protein Data Bank: 5fd2. CMCF-ID Health
Seattle Structural Genomics Center for Infectious Disease (SSGCID) (2016). Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline--tRNA ligase) from Plasmodium falciparum in complex with TCMDC-124506. Protein Data Bank: 4wi1. CMCF-ID Health
Beyrakhova, K.; van Straaten, K.; Cygler, M. (2016). Structure of the effector protein LpiR1 (Lpg0634) from Legionella pneumophila. Protein Data Bank: 5jg4. CMCF-ID Health
Fischmann, T.O. (2016). S. aureus MnaA-UDP co-structure. Protein Data Bank: 5enz. CMCF-ID Health
Jayaram, H.; Poy, F.; Setser, J.W.; Bellon, S.F. (2016). Crystal structure of the bromodomain of human CREBBP bound to the benzodiazepinone G02778174. Protein Data Bank: 5i86. CMCF-ID Health
Bie, H.Y.; Yin, J.; James, M.N.G.; TB Structural Genomics Consortium (TBSGC) (2016). Crystal structure of beta subunit of acyl-CoA carboxylase AccD1 from Mycobacterium tuberculosis. Protein Data Bank: 4q0g. CMCF-ID Health
Ramaswamy; Raghavendran (2016). Structural characterization of TbFam50, TbPSSA2, and TCCISSA, surface proteins expressed by the trypanosome inside the tsetse vector. Supervisor: Boulanger, Martin. J. British Columbia, Canada: University of Victoria. http://hdl.handle.net/1828/7332. CMCF-BM, CMCF-ID Health
Lugo, Miguel R.; Ravulapalli, Ravikiran; Dutta, Debajyoti; Rod Merrill, A. (2016). Structural variability of C3larvin toxin. Intrinsic dynamics of the α/β fold of the C3-like group of mono-ADP-ribosyltransferase toxins. Journal of Biomolecular Structure and Dynamics , 2537-2560. 10.1080/07391102.2015.1123189. [PDB: 5dzq] CMCF-ID Health
Chung, Ho-Ryun; Xu, Chao; Fuchs, Alisa; Mund, Andreas; Lange, Martin et al. (2016). PHF13 is a molecular reader and transcriptional co-regulator of H3K4me2/3. eLife 5, e10607. 10.7554/elife.10607. [PDB: 3o70] CMCF-ID Health
Bryson, Steve; Thomson, Christy A.; Risnes, Louise F.; Dasgupta, Somnath; Smith, Kenneth et al. (2016). Structures of Preferred Human IgV Genes–Based Protective Antibodies Identify How Conserved Residues Contact Diverse Antigens and Assign Source of Specificity to CDR3 Loop Variation. Journal of Immunology 196(11) , 4723-4730. 10.4049/jimmunol.1402890. [PDB: 4hh9, 4hha] CMCF-ID Health
Blake, James F.; Burkard, Michael; Chan, Jocelyn; Chen, Huifen; Chou, Kang-Jye et al. (2016). Discovery of (S)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one (GDC-0994), an Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibitor in Early Clinical Development. Journal of Medicinal Chemistry 59(12) , 5650-5660. 10.1021/acs.jmedchem.6b00389. [PDB: 5k4i] CMCF-ID Health
Hughes, Scott J.; Antoshchenko, Tetyana; Chen, Yun; Lu, Hua; Pizarro, Juan C. et al. (2016). Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs. PLoS ONE 11(5) , e0154862. 10.1371/journal.pone.0154862. [PDB: 5evz, 5ex5, 5exw, 5f0x, 5f2r] CMCF-ID Health
Aydin, Halil; Sultana, Azmiri; Li, Sheng; Thavalingam, Annoj; Lee, Jeffrey E. et al. (2016). Molecular architecture of the human sperm IZUMO1 and egg JUNO fertilization complex. Nature 534(7608) , 562-565. 10.1038/nature18595. [PDB: 5f4e, 5f4t, 5f4v] CMCF-ID Health