Publication Beamlines Strategic Pillar
Frigon, Léonie; Pascal, John M (2023). Structural and biochemical analysis of the PARP1-homology region of PARP4/vault PARP. Nucleic Acids Research . 10.1093/nar/gkad1064. [PDB: 8sx1] CMCF-BM Health
Xu, C.; Chung, I.Y.W.; Cygler, M. (2023). Crystal structure of legAS4 from Legionella pneumophila subsp. pneumophila with histone H3 (1-12)peptide. Protein Data Bank: 8swi. CMCF-BM Agriculture
Wang, F.; Cheng, W.; Lv, Z.; Ju, C.; Wang, J. et al. (2023). The Crystal Structure of L-asparaginase from Biortus.. Protein Data Bank: 8wgq. CMCF-BM Agriculture
Wang, F.; Cheng, W.; Lv, Z.; Ju, C.; Wang, J. et al. (2023). The Crystal Structure of JNK3 from Biortus.. Protein Data Bank: 8wgf. CMCF-BM Agriculture
Wang, F.; Cheng, W.; Lv, Z.; Ju, C.; Bao, C. et al. (2023). The Crystal Structure of JMJD2A(M1-L359) from Biortus.. Protein Data Bank: 8wd3. CMCF-BM Agriculture
Tran, T.T.Q.; Pham, N.T.H.; Calmettes, C.; Doucet, N. (2023). Crystal structure of human eosinophil-derived neurotoxin (EDN, ribonuclease 2) in complex with 5'-adenosine monophosphate (AMP). Protein Data Bank: 8f5x. CMCF-BM Agriculture
Li, K.; Tokareva, O.S.; Thomson, T.M.; Verdine, G.L.; McGee, J.H. et al. (2023). Crystal structure of the WWP1 HECT domain in complex with H302, a Helicon Polypeptide. Protein Data Bank: 8ei4. CMCF-BM Agriculture
Frigon, L.; Pascal, J.M. (2023). PARP4 catalytic domain. Protein Data Bank: 8sx1. CMCF-BM Agriculture
Ali, Mohamed (2023). Investigating the role of acetylation of LC3-family proteins in regulating autophagy. Supervisor: Omichinski, James G.. Quebec, Canada: Université de Montréal. http://hdl.handle.net/1866/32170. CMCF-BM Health
Varkaris, Andreas; Pazolli, Ermira; Gunaydin, Hakan; Wang, Qi; Pierce, Levi et al. (2023). Discovery and clinical proof-of-concept of RLY-2608, a first-in-class mutant-selective allosteric PI3Ka inhibitor that decouples anti-tumor activity from hyperinsulinemia. Cancer Discovery . 10.1158/2159-8290.cd-23-0944. [PDB: 8ts7] CMCF-ID Health
Thai, Elaine; Murugan, Rajagopal; Binter, Špela; Burn Aschner, Clare; Prieto, Katherine et al. (2023). Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein. Cell Reports 42(11) , 113330. 10.1016/j.celrep.2023.113330. [PDB: 8fb5] CMCF-ID Health
Smith, Christopher R.; Chen, Dan; Christensen, James G.; Coulombe, René; Féthière, James et al. (2023). Discovery of Five SOS2 Fragment Hits with Binding Modes Determined by SOS2 X-Ray Cocrystallography. Journal of Medicinal Chemistry 67(1) , 774-781. 10.1021/acs.jmedchem.3c02140. [PDB: 8t5g, 8t5m, 8t5r] CMCF-BM, CMCF-ID Health
Kattar, Solomon D.; Gulati, Anmol; Margrey, Kaila A.; Keylor, Mitchell H.; Ardolino, Michael et al. (2023). Discovery of MK-1468: A Potent, Kinome-Selective, Brain-Penetrant Amidoisoquinoline LRRK2 Inhibitor for the Potential Treatment of Parkinson’s Disease. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.3c01486. [PDB: 8six] CMCF-ID Health
Kalliokoski, Tuomo; Kettunen, Henna; Kumpulainen, Esa; Kettunen, Emilia; Thieulin-Pardo, Gabriel et al. (2023). Discovery of novel methionine adenosyltransferase 2A (MAT2A) allosteric inhibitors by structure-based virtual screening. Bioorganic and Medicinal Chemistry Letters 94, 129450. 10.1016/j.bmcl.2023.129450. [PDB: 8p1t, 8p1v] CMCF-ID Health
Cole, Andrew G.; Kultgen, Steven G.; Mani, Nagraj; Quintero, Jorge G.; Yi Fan, Kristi et al. (2023). Design, synthesis, and structure-activity relationship of a bicyclic HBV capsid assembly modulator chemotype leading to the identification of clinical candidate AB-506. Bioorganic and Medicinal Chemistry Letters 94, 129456. 10.1016/j.bmcl.2023.129456. [PDB: 8gbu] CMCF-ID Health