Publication Beamlines Strategic Pillar
Grishin, Andrey M.; Condos, Tara E.C.; Barber, Kathryn R.; Campbell-Valois, François-Xavier; Parsot, Claude et al. (2014). Structural Basis for the Inhibition of Host Protein Ubiquitination by Shigella Effector Kinase OspG. Structure 22(6) , 878-888. 10.1016/j.str.2014.04.010. [PDB: 4q5e, 4q5h] CMCF-ID Health
Elliott, J.Michael; Ultsch, Mark; Lee, Joshua; Tong, Raymond; Takeda, Kentaro et al. (2014). Antiparallel Conformation of Knob and Hole Aglycosylated Half-Antibody Homodimers Is Mediated by a CH2–CH3 Hydrophobic Interaction. Journal of Molecular Biology 426(9) , 1947-1957. 10.1016/j.jmb.2014.02.015. [PDB: 4nqt] CMCF-ID Health
De Schutter, Joris W.; Park, Jaeok; Leung, Chun Yuen; Gormley, Patrick; Lin, Yih-Shyan et al. (2014). Multistage Screening Reveals Chameleon Ligands of the Human Farnesyl Pyrophosphate Synthase: Implications to Drug Discovery for Neurodegenerative Diseases. Journal of Medicinal Chemistry 57(13) , 5764-5776. 10.1021/jm500629e. [PDB: 4lpg, 4lph] CMCF-ID Health
Blattner, Claudia; Lee, Jeong Hyun; Sliepen, Kwinten; Derking, Ronald; Falkowska, Emilia et al. (2014). Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers. Immunity 40(5) , 669-680. 10.1016/j.immuni.2014.04.008. [PDB: 4nug] CMCF-ID Health
Bertwistle, Drew; Vogt, Linda; Aamudalapalli, Hari Babu; Palmer, David R. J.; Sanders, David A. R. et al. (2014). Purification, crystallization and room-temperature X-ray diffraction of inositol dehydrogenase LcIDH2 fromLactobacillus caseiBL23. Acta Crystallographica Section F Structural Biology and Crystallization Communications 70(7) , 979-983. 10.1107/s2053230x14011595. CMCF-ID Health
Min Xu; Mercedesz Balazs; Ning CHAI; Nancy Chiang; Henry Chiu et al. (2014). Anti-hemagglutinin antibodies and methods of use. Patent Number: WO2014078268A2. CMCF-ID Health
Xu, C.; Tempel, W.; He, H.; Wu, X.; Seitova, A. et al. (2014). Crystal structure of TBL1XR1 WD40 repeats. Protein Data Bank: 4lg9. CMCF-ID Agriculture
Sridhar, V.; Badger, J.; Logan, C.; Chie-Leon, B.; NIenaber, V. et al. (2014). Crystal structure of PDE10A2 with fragment ZT0120 (7-chloroquinolin-4-ol). Protein Data Bank: 4mrw. CMCF-ID Health
Sridhar, V.; Badger, J.; Logan, C.; Chie-Leon, B.; Nienaber, V. et al. (2014). Crystal structure of PDE10A2 with fragment ZT1595 (2-[(quinolin-7-yloxy)methyl]quinoline). Protein Data Bank: 4msc. CMCF-ID Health
Sridhar, V.; Badger, J.; Logan, C.; Chie-Leon, B.; Nienaber, V. et al. (2014). Crystal structure of PDE10A2 with fragment ZT1597 (2-({[(2S)-2-methyl-2,3-dihydro-1,3-benzothiazol-5-yl]oxy}methyl)quinoline). Protein Data Bank: 4mse. CMCF-ID Health
Sridhar, V.; Badger, J.; Logan, C.; Chie-Leon, B.; Nienaber, V. et al. (2014). Crystal structure of PDE10A2 with fragment ZT0443 (6-chloropyrimidine-2,4-diamine). Protein Data Bank: 4ms0. CMCF-ID Health
Sridhar, V.; Badger, J.; Logan, C.; Chie-Leon, B.; Nienaber, V. et al. (2014). Crystal structure of PDE10A2 with fragment ZT0429 (4-methyl-3-nitropyridin-2-amine). Protein Data Bank: 4mrz. CMCF-ID Health
Sridar, V.; Badger, J.; Logan, C.; Chie-Leon, B.; Nienaber, V. et al. (2014). Crystal structure of PDE10A2 with fragment ZT0449 (5-nitro-1H-benzimidazole). Protein Data Bank: 4msa. CMCF-ID Health
Persch, E.; Bryson, S.; Pai, E.F.; Krauth-Siegel, R.L.; Diederich, F. et al. (2014). Crystal structure of Trypanothione Reductase from Trypanosoma brucei in complex with inhibitor EP127 (5-{5-[1-(PYRROLIDIN-1-YL)CYCLOHEXYL]-1,3-THIAZOL-2-YL}-1H-INDOLE). Protein Data Bank: 4nev. CMCF-ID Health
Park, J.; Leung, C.Y.; Tsantrizos, Y.S.; Berghuis, A.M. (2014). Crystal structure of human FPPS in complex with CL03093. Protein Data Bank: 4lph. CMCF-ID Health