Gorelik, Alexei; Illes, Katalin; Superti-Furga, Giulio; Nagar, Bhushan (2016). Structural Basis for Nucleotide Hydrolysis by the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3A. Journal of Biological Chemistry 291(12) , 6376-6385. 10.1074/jbc.m115.711085. [PDB: 5fc1, 5fc6, 5fc7, 5fca, 5fcb] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
Liu, Yanjie; Frirdich, Emilisa; Taylor, Jennifer A.; Chan, Anson C. K.; Blair, Kris M. et al. (2016). A Bacterial Cell Shape-Determining Inhibitor. ACS Chemical Biology 11(4) , 981-991. 10.1021/acschembio.5b01039. [PDB: 5d2r] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Hamilton, Jordan G.; Farrell, Richard E.; Chen, Ning; Feng, Renfei; Reid, Joel et al. (2016). Characterizing Zinc Speciation in Soils from a Smelter-Affected Boreal Forest Ecosystem. Journal of Environmental Quality 45(2) , 684-692. 10.2134/jeq2015.03.0145. |
CMCF-BM, HXMA, VESPERS |
Peer-Reviewed Article |
Environment |
Bergeron, Julien R.C.; Fernández, Lucia; Wasney, Gregory A.; Vuckovic, Marija; Reffuveille, Fany et al. (2016). The Structure of a Type 3 Secretion System (T3SS) Ruler Protein Suggests a Molecular Mechanism for Needle Length Sensing. Journal of Biological Chemistry 291(4) , 1676-1691. 10.1074/jbc.m115.684423. [PDB: 5cuk, 5cul] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
Argyropoulos, Panos; Bergeret, Fabien; Pardin, Christophe; Reimer, Janice M.; Pinto, Atahualpa et al. (2016). Towards a characterization of the structural determinants of specificity in the macrocyclizing thioesterase for deoxyerythronolide B biosynthesis. Biochimica et Biophysica Acta - General Subjects 1860(3) , 486-497. 10.1016/j.bbagen.2015.11.007. [PDB: 5d3k] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Hanan, Emily J.; Baumgardner, Matt; Bryan, Marian C.; Chen, Yuan; Eigenbrot, Charles et al. (2016). 4-Aminoindazolyl-dihydrofuro[3,4- d ]pyrimidines as non-covalent inhibitors of mutant epidermal growth factor receptor tyrosine kinase. Bioorganic and Medicinal Chemistry Letters 26(2) , 534-539. 10.1016/j.bmcl.2015.11.078. [PDB: 5edp, 5edq] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Conly; Cuylar (2016). Determination of the Structural Allosteric Inhibitory Mechanism of Dihydrodipicolinate Synthase. Supervisor: Sanders, David A.; Palmer, David R.. SK, Canada: University of Saskatchewan. http://hdl.handle.net/10388/ETD-2015-11-2317. |
CMCF-BM, CMCF-ID |
Masters Thesis |
Health |
Atwell, S.; Leaver-Fay, A.; Froning, K.J.; Aldaz, H.; Pustilnik, A. et al. (2016). Fc Heterodimer Design 11.2 Y349S/K370Y + E357D/S364Q. Protein Data Bank: 5dj0. |
CMCF-BM |
PDB Deposition |
Agriculture |
Mallette, E.; Mann, E.; Whitfield, C.; Kimber, M.S. (2016). The structure of the kdo-capped saccharide binding subunit of the O-12 specific ABC transporter, Wzt. Protein Data Bank: 5hno. |
CMCF-BM |
PDB Deposition |
Agriculture |
Mallette, E.; Mann, E.; Whitfield, C.; Kimber, M.S. (2016). The structure of the kdo-capped saccharide binding subunit of the O-12 specific ABC transporter, Wzt. Protein Data Bank: 5hnp. |
CMCF-BM |
PDB Deposition |
Health |
Gorelik, A.; Illes, K.; Superti-Furga, G.; Nagar, B. (2016). Murine SMPDL3A in presence of excess zinc. Protein Data Bank: 5fca. |
CMCF-BM |
PDB Deposition |
Agriculture |
Chan, A.C.; Murphy, M.E. (2016). Inhibitor Bound Cell Shape Determinant Protein Csd4 from Helicobacter pylori. Protein Data Bank: 5d2r. |
CMCF-BM |
PDB Deposition |
Health |
Kobylarz; Marek John (2016). Siderophore-mediated iron metabolism in Staphylococcus aureus. Supervisor: Murphy, Michael. British Columbia, Canada: University of British Columbia. http://hdl.handle.net/2429/57023. |
CMCF-BM |
Doctoral Thesis |
Health |
Wu, Wen-Lian; Hao, Jinsong; Domalski, Martin; Burnett, Duane A.; Pissarnitski, Dmitri et al. (2016). Discovery of Novel Tricyclic Heterocycles as Potent and Selective DPP-4 Inhibitors for the Treatment of Type 2 Diabetes. ACS Medicinal Chemistry Letters 7(5) , 498-501. 10.1021/acsmedchemlett.6b00027. [PDB: 5i7u] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Shaw, Alice T.; Friboulet, Luc; Leshchiner, Ignaty; Gainor, Justin F.; Bergqvist, Simon et al. (2016). Resensitization to Crizotinib by the LorlatinibALKResistance Mutation L1198F. New England Journal of Medicine 374(1) , 54-61. 10.1056/nejmoa1508887. [PDB: 5a9u, 5aac] |
CMCF-ID |
Peer-Reviewed Article |
Health |