Lyons, Bronwyn; Lugo, Miguel R.; Carlin, Stephanie; Lidster, Taylor; Merrill, A. Rod et al. (2018). Characterization of the catalytic signature of Scabin toxin, a DNA-targeting ADP-ribosyltransferase. Biochemical Journal 475(1) , 225-245. 10.1042/bcj20170818. [PDB: 5tlb, 5uvq, 6apy] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Mahoney, Sarah J.; Narayan, Sridhar; Molz, Lisa; Berstler, Lauren A.; Kang, Seong A. et al. (2018). A small molecule inhibitor of Rheb selectively targets mTORC1 signaling. Nature Communications 9(1) . 10.1038/s41467-018-03035-z. [PDB: 6bt0] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Mahoney, S.J. (2018). CRYSTAL STRUCTURE OF RHEB IN COMPLEX WITH COMPOUND NR1. Protein Data Bank: 6bt0. |
CMCF-ID |
PDB Deposition |
Health |
Marshall; Jeremy Davin Seiberling (2018). Structural analysis of the p85 BH domain in complex with binding partners and effect of mutations. Supervisor: Anderson, Deborah. SK, Canada: University of Saskatchewan. http://hdl.handle.net/10388/8321. |
CMCF-BM, CMCF-ID |
Masters Thesis |
Health |
McAllister, Laura A.; Butler, Christopher R.; Mente, Scot; O’Neil, Steven V.; Fonseca, Kari R. et al. (2018). Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation. Journal of Medicinal Chemistry 61(7) , 3008-3026. 10.1021/acs.jmedchem.8b00070. [PDB: 6bq0] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Pandit, J. (2018). Structure of human monoacylglycerol lipase bound to a covalent inhibitor. Protein Data Bank: 6bq0. |
CMCF-ID |
PDB Deposition |
Health |
Picard, Marie-Ève; Nisole, Audrey; Béliveau, Catherine; Sen, Stephanie; Barbar, Aline et al. (2018). Structural characterization of a lepidopteran type-II farnesyl diphosphate synthase from the spruce budworm, Choristoneura fumiferana : Implications for inhibitor design. Insect Biochemistry and Molecular Biology 92, 84-92. 10.1016/j.ibmb.2017.11.011. [PDB: 6b02, 6b04, 6b06] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Pluvinage, Benjamin; Grondin, Julie M.; Amundsen, Carolyn; Klassen, Leeann; Moote, Paul E. et al. (2018). Molecular basis of an agarose metabolic pathway acquired by a human intestinal symbiont. Nature Communications 9(1) . 10.1038/s41467-018-03366-x. [PDB: 5t9a, 5t9x, 5ta0, 5ta1, 5ta5, 5ta7, 5ta9] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
Seattle Structural Genomics Center for Infectious Disease (SSGCID) (2018). Crystal structure of glycylpeptide N-tetradecanoyltransferase from Plasmodium vivax in complex with inhibitor IMP-0001114. Protein Data Bank: 5v0x. |
CMCF-ID |
PDB Deposition |
Agriculture |
Seattle Structural Genomics Center for Infectious Disease (SSGCID) (2018). Crystal structure of glycylpeptide N-tetradecanoyltransferase from Plasmodium vivax in complex with inhibitor IMP-0001088. Protein Data Bank: 5v0w. |
CMCF-ID |
PDB Deposition |
Agriculture |
Seattle Structural Genomics Center for Infectious Disease (SSGCID) (2018). Crystal Structure of Lysyl-tRNA Synthetase from Cryptosporidium parvum complexed with L-Lysylsulfamoyl Adenosine. Protein Data Bank: 6c86. |
CMCF-ID |
PDB Deposition |
Health |
Seirafi, Marjan (2018). Structural studies of parkin activation. Supervisor: Gehring, Kalle. QC, Canada: McGill University. https://escholarship.mcgill.ca/concern/theses/f1881p410. |
CMCF-ID |
Doctoral Thesis |
Health |
Sicard, T.; Ereno Orbea, J.; Julien, J.-P. (2018). LL2 Fab in complex with anti-Kappa VHH domain. Protein Data Bank: 6ana. |
CMCF-ID |
PDB Deposition |
Health |
Sun, Luxin (2018). Involvement of BRCT Family Proteins in DNA Damage Response. Supervisor: Glover, Mark. Alberta, Canada: University of Alberta. https://doi.org/10.7939/R3CZ32K9V. |
CMCF-BM, CMCF-ID |
Doctoral Thesis |
Health |
Ulaganathan, ThirumalaiSelvi; Helbert, William; Kopel, Moran; Banin, Ehud; Cygler, Miroslaw et al. (2018). Structure–function analyses of a PL24 family ulvan lyase reveal key features and suggest its catalytic mechanism. Journal of Biological Chemistry 293(11) , 4026-4036. 10.1074/jbc.ra117.001642. [PDB: 6byp, 6byt, 6byx] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |