| Methot, Joey L.; Zhou, Hua; Kattar, Sam D.; McGowan, Meredeth A.; Wilson, Kevin et al. (2019). Structure Overhaul Affords a Potent Purine PI3Kδ Inhibitor with Improved Tolerability. Journal of Medicinal Chemistry 62(9) . 10.1021/acs.jmedchem.8b01818. [PDB: 6mul] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Newson, JoshuaP.M.; Scott, NichollasE.; Yeuk Wah Chung, Ivy; Wong Fok Lung, Tania; Giogha, Cristina et al. (2019). Salmonella Effectors SseK1 and SseK3 Target Death Domain Proteins in the TNF and TRAIL Signaling Pathways*. Molecular and Cellular Proteomics 18(6) , 1138-1156. 10.1074/mcp.ra118.001093. [PDB: 6cgi, 6dus] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| O'Neill, D. (2019). CRYSTAL STRUCTURE OF SESTRIN2 IN COMPLEX WITH NV-0005138. Protein Data Bank: 6n0m. |
CMCF-ID |
PDB Deposition |
Health |
| Rahfeld, Peter; Sim, Lyann; Moon, Haisle; Constantinescu, Iren; Morgan-Lang, Connor et al. (2019). An enzymatic pathway in the human gut microbiome that converts A to universal O type blood. Nature Microbiology 4(9) . 10.1038/s41564-019-0469-7. [PDB: 6n1a] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Raman, S.; Beilschmidt, M.; Fransson, J.; Julien, J.P. (2019). Crystal structure of Frizzled 7 CRD in complex with F7.B Fab. Protein Data Bank: 6o3a. |
CMCF-ID |
PDB Deposition |
Health |
| Raman, S.; Beilschmidt, M.; Fransson, J.; Julien, J.P. (2019). Crystal structure of Frizzled 5 CRD in complex with F2.I Fab. Protein Data Bank: 6o39. |
CMCF-ID |
PDB Deposition |
Health |
| Riggs, Jennifer R.; Elsner, Jan; Cashion, Dan; Robinson, Dale; Tehrani, Lida et al. (2019). Design and Optimization Leading to an Orally Active TTK Protein Kinase Inhibitor with Robust Single Agent Efficacy. Journal of Medicinal Chemistry 62(9) , 4401-4410. 10.1021/acs.jmedchem.8b01869. [PDB: 6n6o] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Sachdev Sidhu; Linda Beatty; Andreas Ernst (2019). Specific active site inhibitors of enzymes or substrate binding partners and methods of producing same. Patent Number: US20190194270A1. |
CMCF-ID |
Patent |
Health |
| Sack, J.S. (2019). Crystal structure of JAK3 kinase domain in complex with a pyrrolopyridazine carboxamide inhibitor. Protein Data Bank: 6ny4. |
CMCF-ID |
PDB Deposition |
Health |
| Sahtout, Naheda; Kuttiyatveetil, Jijin R.A.; Sanders, David A.R. (2019). Structure and function of the putative thioredoxin 1 from the thermophilic eubacterium Thermosipho africanus strain TCF52B. Biochimica et Biophysica Acta - Proteins and Proteomics 1867(4) , 426-433. 10.1016/j.bbapap.2019.01.011. [PDB: 6mos] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Sim, L.; Rahfeld, P.; Withers, S.G. (2019). Crystal structure of an N-acetylgalactosamine deacetylase from F. plautii in complex with blood group B trisaccharide. Protein Data Bank: 6n1b. |
CMCF-ID |
PDB Deposition |
Health |
| Sim, L.; Rahfeld, P.; Withers, S.G. (2019). Crystal structure of an N-acetylgalactosamine deacetylase from F. plautii. Protein Data Bank: 6n1a. |
CMCF-ID |
PDB Deposition |
Health |
| Simonetta, K.R.; Clifton, M.C.; Walter, R.L.; Ranieri, G.M.; Carter, J.J. et al. (2019). Monophosphorylated pSer33 b-Catenin peptide bound to b-TrCP/Skp1 Complex. Protein Data Bank: 6m94. |
CMCF-ID |
PDB Deposition |
Health |
| Simonetta, K.R.; Clifton, M.C.; Walter, R.L.; Ranieri, G.M.; Carter, J.J. et al. (2019). Monophosphorylated pSer33 b-Catenin peptide, b-TrCP/Skp1, NRX-103094 ternary complex. Protein Data Bank: 6m91. |
CMCF-ID |
PDB Deposition |
Health |
| Simonetta, K.R.; Clifton, M.C.; Walter, R.L.; Ranieri, G.M.; Carter, J.J. et al. (2019). Monophosphorylated pSer33 b-Catenin peptide, b-TrCP/Skp1, NRX-2663 ternary complex. Protein Data Bank: 6m92. |
CMCF-ID |
PDB Deposition |
Health |