Norman, Mark H.; Andrews, Kristin L.; Bo, Yunxin Y.; Booker, Shon K.; Caenepeel, Sean et al. (2012). Selective Class I Phosphoinositide 3-Kinase Inhibitors: Optimization of a Series of Pyridyltriazines Leading to the Identification of a Clinical Candidate, AMG 511. Journal of Medicinal Chemistry 55(17) , 7796-7816. 10.1021/jm300846z. [PDB: 4flh] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Ratto, Marcelo H.; Leduc, Yvonne A.; Valderrama, Ximena P.; van Straaten, Karin E.; Delbaere, Louis T. J. et al. (2012). The nerve of ovulation-inducing factor in semen. Proceedings of the National Academy of Sciences of the United States of America 109(37) , 15042-15047. 10.1073/pnas.1206273109. [PDB: 4efv] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Shi, Rong; Munger, Christine; Kalan, Lindsay; Sulea, Traian; Wright, Gerard D. et al. (2012). Sulfonation of glycopeptide antibiotics by sulfotransferase StaL depends on conformational flexibility of aglycone scaffold. Proceedings of the National Academy of Sciences of the United States of America 109(29) , 11824-11829. 10.1073/pnas.1205377109. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Siarheyeva, Alena; Senisterra, Guillermo; Allali-Hassani, Abdellah; Dong, Aiping; Dobrovetsky, Elena et al. (2012). An Allosteric Inhibitor of Protein Arginine Methyltransferase 3. Structure 20(8) , 1425-1435. 10.1016/j.str.2012.06.001. [PDB: 3smq] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Wheatley, Robert W.; Zheng, Ruixiang Blake; Richards, Michele R.; Lowary, Todd L.; Ng, Kenneth K.S. et al. (2012). Tetrameric Structure of the GlfT2 Galactofuranosyltransferase Reveals a Scaffold for the Assembly of Mycobacterial Arabinogalactan. Journal of Biological Chemistry 287(33) , 28132-28143. 10.1074/jbc.m112.347484. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Yuchi, Zhiguang; Lau, Kelvin; Van Petegem, Filip (2012). Disease Mutations in the Ryanodine Receptor Central Region: Crystal Structures of a Phosphorylation Hot Spot Domain. Structure 20(7) , 1201-1211. 10.1016/j.str.2012.04.015. [PDB: 4ert, 4erv, 4etv] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Ukpabi, Georgia Nonye (2012). Structural basis for heme degradation in Staphylococcus aureus. Supervisor: Murphy, Michael. British Columbia, Canada: University of British Columbia. http://hdl.handle.net/2429/42749. |
CMCF-ID |
Masters Thesis |
Health |
J. Michael ELLIOTT; Justin Scheer (2012). Fc VARIANTS AND METHODS FOR THEIR PRODUCTION. Patent Number: WO2012106587A1. |
CMCF-ID |
Patent |
Health |
Hehemann, J.H.; Kelly, A.G.; Pudlo, N.A.; Martens, E.C.; Boraston, A.B. et al. (2012). BpGH86A: A beta-porphyranase of glycoside hydrolase family 86 from the human gut bacterium Bacteroides plebeius. Protein Data Bank: 4aw7. |
CMCF-ID |
PDB Deposition |
Health |
Hong, B.S.; Dimov, S.; Tempel, W.; Bountra, C.; Arrowsmith, C.H. et al. (2012). Crystal Structure of Certhrax. Protein Data Bank: 4gf1. |
CMCF-ID |
PDB Deposition |
Health |
Ravulapalli, R.; Kimber, M.S.; Merrill, A.R. (2012). Catalytic domain of VahC from Aeromonas hydrophila. Protein Data Bank: 4fml. |
CMCF-ID |
PDB Deposition |
Health |
Shi, R.; Cygler, M. (2012). Crystal Structure of the glycopeptide antibiotic sulfotransferase StaL complexed with A3P and desulfo-A47934.. Protein Data Bank: 4eec. |
CMCF-ID |
PDB Deposition |
Health |
Visschedyk, D.D.; Dimov, S.; Kimber, M.S.; Park, H.W.; Merrill, A.R. et al. (2012). Full-length Certhrax toxin from Bacillus cereus in complex with Inhibitor P6. Protein Data Bank: 4fxq. |
CMCF-ID |
PDB Deposition |
Health |
Whittington, D.A.; Epstein, L.F.; Chen, H. (2012). Crystal structure of human anaplastic lymphoma kinase in complex with piperidine-carboxamide inhibitor 2. Protein Data Bank: 4fnz. |
CMCF-ID |
PDB Deposition |
Health |
Whittington, D.A.; Tang, J.; Yakowec, P. (2012). Crystal structure of human PI3K-gamma in complex with AMG511. Protein Data Bank: 4flh. |
CMCF-ID |
PDB Deposition |
Health |