| Noach, Ilit; Ficko-Blean, Elizabeth; Pluvinage, Benjamin; Stuart, Christopher; Jenkins, Meredith L. et al. (2017). Recognition of protein-linked glycans as a determinant of peptidase activity. Proceedings of the National Academy of Sciences of the United States of America 114(5) , E679-E688. 10.1073/pnas.1615141114. [PDB: 5kd5, 5kd8, 5kdn, 5kdu, 5kdv, 5kdw, 5kdx] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Park, Jaeok; Leung, Chun Yuen; Matralis, Alexios N.; Lacbay, Cyrus M.; Tsakos, Michail et al. (2017). Pharmacophore Mapping of Thienopyrimidine-Based Monophosphonate (ThP-MP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase. Journal of Medicinal Chemistry 60(5) , 2119-2134. 10.1021/acs.jmedchem.6b01888. [PDB: 5juz, 5jv1] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Park, Jaeok; Zielinski, Michal; Magder, Alexandr; Tsantrizos, Youla S.; Berghuis, Albert M. et al. (2017). Human farnesyl pyrophosphate synthase is allosterically inhibited by its own product. Nature Communications 8(1) . 10.1038/ncomms14132. [PDB: 5ja0] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Planken, Simon; Behenna, Douglas C.; Nair, Sajiv K.; Johnson, Theodore O.; Nagata, Asako et al. (2017). Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR. Journal of Medicinal Chemistry 60(7) , 3002-3019. 10.1021/acs.jmedchem.6b01894. [PDB: 5ugc] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Stanger, Frédéric V.; de Beer, Tjaart A.P.; Dranow, David M.; Schirmer, Tilman; Phan, Isabelle et al. (2017). The BID Domain of Type IV Secretion Substrates Forms a Conserved Four-Helix Bundle Topped with a Hook. Structure 25(1) , 203-211. 10.1016/j.str.2016.10.010. [PDB: 4yk1] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Wahba, Haytham M.; Stevenson, Michael J.; Mansour, Ahmed; Sygusch, Jurgen; Wilcox, Dean E. et al. (2017). Structural and Biochemical Characterization of Organotin and Organolead Compounds Binding to the Organomercurial Lyase MerB Provide New Insights into Its Mechanism of Carbon–Metal Bond Cleavage. Journal of the American Chemical Society 139(2) , 910-921. 10.1021/jacs.6b11327. [PDB: 5u79, 5u7b, 5u7c, 5u82, 5u83] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Abdelgawwad; Haytham Mohamed Gamaleldin Wahba (2017). Structural and Biochemical Characterization of the Organomercurial Lyase MerB. Supervisor: Omichinski, James G.. QC, Canada: University of Montreal. http://hdl.handle.net/1866/18547. |
CMCF-ID |
Doctoral Thesis |
Agriculture |
| Gobeil; Sophie (2017). Verification of the correlation between function, structure and dynamics on a recombinant evolutionary pathway β-lactamases TEM-1 and PSE-4. Supervisor: Pelletier, Joelle. QC, Canada: University of Montreal. http://hdl.handle.net/1866/18543. |
CMCF-ID |
Doctoral Thesis |
Agriculture |
| Liu; Xiaohu (2017). Functional and structural study of the AHI-1 SH3 domain, characterization of the BCR-ABL-AHI-1-Dynamin-2 protein complex and investigation of oncogenic roles of dynamin-2 in chronic myeloid leukemia. Supervisor: Jiang, Xiaoyan. BC, Canada: University of British Columbia. http://hdl.handle.net/2429/60191. |
CMCF-ID |
Doctoral Thesis |
Agriculture |
| Radka; Christopher D. (2017). Structure/Function Studies of Yersinia pestis Metal Transport Systems. Supervisor: Aller, Stephen G.; DeLucas, Lawrence J.. Alabama, USA: University of Alabama at Birmingham. https://uab.primo.exlibrisgroup.com/permalink/01AL_UALB/5cjhn9/alma991002054550203176. |
CMCF-ID |
Doctoral Thesis |
Agriculture |
| Chan, A.C.; Murphy, M.E. (2017). IRON AND COPPER-BOUND P19 FROM CAMPYLOBACTER JEJUNI UNDER OXIDIZING CONDITIONS. Protein Data Bank: 5i0v. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Cook, J.D.; Sultana, A.; Lee, J.E. (2017). Crystal structure of the infectious salmon anemia virus (ISAV) hemagglutinin-esterase protein. Protein Data Bank: 5t9y. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Cook, J.D.; Sultana, A.; Lee, J.E. (2017). Crystal structure of the infectious salmon anemia virus (ISAV) HE viral receptor complex. Protein Data Bank: 5t96. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Gonzalez, J.M. (2017). Malate dehydrogenase from Methylobacterium extorquens, complexed with NAD. Protein Data Bank: 5ujk. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Hughes, S.J.; Lyle, A.G.; Song, J.H.; Antoshchenko, T.; Park, H. et al. (2017). Crystal structure of Enterococcus faecalis lipoate-protein ligase A (lplA-1) in complex with lipoic acid. Protein Data Bank: 5ij6. |
CMCF-ID |
PDB Deposition |
Agriculture |