| Wrobleski, Stephen T.; Moslin, Ryan; Lin, Shuqun; Zhang, Yanlei; Spergel, Steven et al. (2019). Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165. Journal of Medicinal Chemistry 62(20) . 10.1021/acs.jmedchem.9b00444. [PDB: 6nzq, 6nzr] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Schrag, Joseph D.; Picard, Marie-Ève; Gaudreault, Francis; Gagnon, Louis-Patrick; Baardsnes, Jason et al. (2019). Binding symmetry and surface flexibility mediate antibody self-association. mAbs 11(7) , 1-19. 10.1080/19420862.2019.1632114. [PDB: 6mxr, 6mxs, 6my4, 6my5] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Kuatsjah, Eugene; Verstraete, Meghan M.; Kobylarz, Marek J.; Liu, Alvin K.N.; Murphy, Michael E.P. et al. (2019). Identification of functionally important residues and structural features in a bacterial lignostilbene dioxygenase. Journal of Biological Chemistry 294(35) , jbc.RA119.009428. 10.1074/jbc.ra119.009428. [PDB: 6ojt] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Lu, Zhonghui; Duan, James J.-W.; Xiao, Haiyun; Neels, James; Wu, Dauh-Rurng et al. (2019). Identification of potent, selective and orally bioavailable phenyl ((R)-3-phenylpyrrolidin-3-yl)sulfone analogues as RORγt inverse agonists. Bioorganic and Medicinal Chemistry Letters 29(16) . 10.1016/j.bmcl.2019.06.036. [PDB: 6p9f] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Hobbs, Joanne K.; Pluvinage, Benjamin; Robb, Melissa; Smith, Steven P.; Boraston, Alisdair B. et al. (2019). Two complementary α-fucosidases from Streptococcus pneumoniae promote complete degradation of host-derived carbohydrate antigens. Journal of Biological Chemistry 294(34) , jbc.RA119.009368. 10.1074/jbc.ra119.009368. [PDB: 6or4] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Caveney, Nathanael A.; Pavlin, Anja; Caballero, Guillermo; Bahun, Miha; Hodnik, Vesna et al. (2019). Structural Insights into Bacteriophage GIL01 gp7 Inhibition of Host LexA Repressor. Structure 27(7) . 10.1016/j.str.2019.03.019. [PDB: 6n7o] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Chen, Y.; Antoshchenko, T.; Smil, D.; Zepeda, C.; Huang, Y. et al. (2019). Crystal structure of human GRP78 in complex with (2R,3R,4S,5R)-2-(6-amino-8-((2-chlorobenzyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. Protein Data Bank: 6dws. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Hettle, A.G.; Boraston, A.B. (2019). Crystal structure of the sulfatase PsS1_NC C84A with bound sulfate ion. Protein Data Bank: 6ptk. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Hettle, A.G.; Boraston, A.B. (2019). Crystal structure of PsS1_19B C77S in complex with kappa-neocarrabiose. Protein Data Bank: 6psm. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Hettle, A.G.; Boraston, A.B. (2019). Crystal structure of apo PsS1_NC. Protein Data Bank: 6pt4. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Hettle, A.G.; Boraston, A.B. (2019). Crystal structure of apo PsS1_19B. Protein Data Bank: 6prm. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Radka, C.D.; Labiuk, S.L.; DeLucas, L.J.; Aller, S.G. (2019). Holo YfeA reconstituted by zinc soaking. Protein Data Bank: 6q1d. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Sahtout, N.; Kuttiyatveetil, J.R.; Sanders, D.A.R. (2019). Structure of thioredoxin 1 from the thermophilic eubacterium Thermosipho africanus TCF52B. Protein Data Bank: 6mos. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Du, Y.L.; Higgins, M.A.; Zhao, G.; Ryan, K.S. (2019). N-demethylindolmycin synthase (PluN2) in complex with N-demethylindolmycin. Protein Data Bank: 6p29. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Kuatsjah, E.; Verstraete, M.M.; Kobylarz, M.J.; Liu, A.K.N.; Murphy, M.E.P. et al. (2019). Crystal structure of Sphingomonas paucimobilis TMY1009 LsdA phenylazophenol complex. Protein Data Bank: 6ojt. |
CMCF-ID |
PDB Deposition |
Agriculture |