Publication Beamlines Strategic Pillar
Chen, P.; Lamer, T.; Vederas, J.C.; Lemieux, M.J. (2025). Crystal structures of a cyanobacterial DAP epimerase bound to D,L-alpha-methyl DAP. Protein Data Bank: 9mrv. CMCF-BM Agriculture
Chen, P.; Lamer, T.; Vederas, J.C.; Lemieux, M.J. (2025). Crystal structures of a cyanobacterial DAP epimerase bound to either D,L-aziDAP or D,L-alpha-methyl DAP. Protein Data Bank: 9mro. CMCF-BM Agriculture
Dodda, Leela S.; Campos, Sebastien; Ciccone, David; Carreiro, Samantha; Leit, Silvana et al. (2025). Knowledge and Structure-Based Drug Design of 15-PGDH Inhibitors. Journal of Medicinal Chemistry 68(17) , 18436-18462. 10.1021/acs.jmedchem.5c01231. [PDB: 9pfl] CMCF-BM Materials
Throner, Scott; Feng, Tianshu; Andersen, Jannik N.; Bandi, Madhavi; Engel, Justin L. et al. (2025). Discovery of TNG-6132, a potent, selective, and orally bioavailable USP1 inhibitor. Bioorganic and Medicinal Chemistry Letters 124, 130262. 10.1016/j.bmcl.2025.130262. [PDB: 9n9y] CMCF-BM Health
Tran, Norman; Frenette, Aaron; Holyoak, Todd (2025). Structure of the Thomasclavelia ramosa immunoglobulin A protease reveals a modular and minimizable architecture distinct from other immunoglobulin A proteases. Proceedings of the National Academy of Sciences of the United States of America 122(35) . 10.1073/pnas.2503549122. [PDB: 9ekk, 9ekm, 9ekn] CMCF-BM Agriculture
Rolfe, Nicolas; Schroeter, Kurt L.; Forrester, Taylor JB.; Kimber, Matthew S.; Seah, Stephen YK. et al. (2025). Sal is a proteobacterial bile acid aldolase that repurposes key thiolase catalytic residues for retroaldol cleavage of C5 steroid side chains. Journal of Biological Chemistry 301(8) , 110439. 10.1016/j.jbc.2025.110439. [PDB: 9myr] CMCF-BM Agriculture
Rolfe, Nicolas; Myskiw, Dustin; Patton, Matthew T.; Forrester, Taylor J. B.; Kimber, Matthew S. et al. (2025). Sad from Proteobacteria is a Structurally Distinct ALDH3 Enzyme Specialized for the Oxidation of Steroidal Aldehydes. Biochemistry 64(17) , 3735-3744. 10.1021/acs.biochem.5c00213. [PDB: 9nxl] CMCF-BM Agriculture
Barghash, Marim M.; Mabanglo, Mark F.; Hoff, Samuel E.; Brozdnychenko, Dmytro; Wong, Keith S. et al. (2025). Small molecule dysregulation of ClpP activity via bidirectional allosteric pathways. Structure . 10.1016/j.str.2025.07.013. [PDB: 9mjp] CMCF-BM Agriculture
Zhang, D.; Saldajeno-Concar, M.; Tomlinson, A.C.A.; Yano, J.K.; Knox, J.E. et al. (2025). Tricomplex of RMC-9945, KRAS G12D, and CypA. Protein Data Bank: 9cta. CMCF-ID Agriculture
Zhang, D.; Bar Ziv, T.; Tomlinson, A.C.A.; Saldajeno-Concar, M.; Yano, J.K. et al. (2025). Tri-complex of zoldonrasib (RMC-9805), KRAS G12D, and CypA. Protein Data Bank: 9ctb. CMCF-ID Agriculture
Zhang, D.; Bar Ziv, T.; Knox, J.E.; Yano, J.K. (2025). Tricomplex of Compound 3, KRAS G12D, and CypA. Protein Data Bank: 9ct9. CMCF-ID Agriculture
Zhang, D.; Bar Ziv, T.; Knox, J.E.; Yano, J.K. (2025). Tricomplex of Compound 1, KRAS G12D, and CypA. Protein Data Bank: 9ct7. CMCF-ID Agriculture
Zeytuni, N.; Yang, Z.; Odeh-Ahmed, A.; Abdoli, A.; Leyton, V.J. et al. (2025). Importin alpha isoform 2 with synthetic zero net-charge nuclear localization signal. Protein Data Bank: 9clg. CMCF-ID Agriculture
Zeytuni, N.; Yang, Z.; Odeh-Ahmed, A.; Abdoli, A.; Leyton, V.J. et al. (2025). Importin alpha isoform 2 with synthetic zero net-charge nuclear localization signal. Protein Data Bank: 9clf. CMCF-ID Agriculture
Zeytuni, N.; Yang, Z.; Odeh-Ahmed, A.; Abdoli, A.; Leyton, V.J. et al. (2025). Importin alpha isoform 2 with synthetic zero net-charge nuclear localization signal. Protein Data Bank: 9cle. CMCF-ID Agriculture