| Li; Tang (2019). Structure-biological function study of 17B-hydroxysteroid dehydrogenase type 1 and reductive steroid enzymes : inhibitor design targeting estrogen-dependent diseases. Supervisor: Lin, Sheng-Xiang. Quebec, Canada: Université Laval. http://hdl.handle.net/20.500.11794/34398. |
CMCF-BM |
Doctoral Thesis |
Health |
| Kimber, M.S.; Mallette, E.; Aggett, R.; Seah, S.Y.K. (2019). Ltp2-ChsH2(DUF35) aldolase. Protein Data Bank: 6ok1. |
CMCF-BM |
PDB Deposition |
Health |
| Kassymbek, Aishabibi; Britten, James F.; Spasyuk, Denis; Gabidullin, Bulat; Nikonov, Georgii I. et al. (2019). Interaction of Multiple Bonds with NacNacGa: Oxidative Cleavage vs Coupling and Cyclization. Inorganic Chemistry 58(13) , 8665-8672. 10.1021/acs.inorgchem.9b01005. |
CMCF-BM |
Peer-Reviewed Article |
Materials |
| Guarne, A.; Almawi, A.W. (2019). Crystal structure of the Bacillus subtilis sliding clamp-MutL complex.. Protein Data Bank: 6e8d. |
CMCF-BM |
PDB Deposition |
Health |
| Doyle, Liam; Ovchinnikova, Olga G.; Myler, Katharine; Mallette, Evan; Huang, Bo-Shun et al. (2019). Biosynthesis of a conserved glycolipid anchor for Gram-negative bacterial capsules. Nature Chemical Biology 15(6) . 10.1038/s41589-019-0276-8. [PDB: 6mgb, 6mgc, 6mgd] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Caveney, Nathanael A.; Caballero, Guillermo; Voedts, Henri; Niciforovic, Ana; Worrall, Liam J. et al. (2019). Structural insight into YcbB-mediated beta-lactam resistance in Escherichia coli. Nature Communications 10(1) . 10.1038/s41467-019-09507-0. [PDB: 6ntz] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Caveney, N.A.; Strynadka, N.C.J. (2019). Crystal structure of GIL01 gp7. Protein Data Bank: 6n7o. |
CMCF-BM |
PDB Deposition |
Health |
| Zhang, Birong; Kiefer, James R.; Blake, Robert A.; Chang, Jae H.; Hartman, Steven et al. (2019). Unexpected equivalent potency of a constrained chromene enantiomeric pair rationalized by co-crystal structures in complex with estrogen receptor alpha. Bioorganic and Medicinal Chemistry Letters 29(7) . 10.1016/j.bmcl.2019.01.036. [PDB: 6dfn] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Yu, C.; Drobnick, J.; Bryan, M.C.; Kiefer, J.; Lupardus, P.J. et al. (2019). Structure of the IRAK4 kinase domain with compound 5. Protein Data Bank: 6o9d. |
CMCF-ID |
PDB Deposition |
Health |
| Yachnin, B.J.; Berghuis, A.M. (2019). Crystal structure of trimethoprim-resistant type II dihydrofolate reductase in complex with a bisbenzimidazole inhibitor. Protein Data Bank: 6ny0. |
CMCF-ID |
PDB Deposition |
Health |
| Xu, C.; Boniecki, M.; Cygler, M. (2019). Structure of the N-terminal domain of effector protein SpvB from Salmonella typhimurium strain LT2. Protein Data Bank: 6p0x. |
CMCF-ID |
PDB Deposition |
Health |
| Xiong; ZiJian (2019). Structural Investigations of Saposin/Hydrolase Systems. Supervisor: Privé, Gilbert. Ontario, Canada: University of Toronto. http://hdl.handle.net/1807/97049. |
CMCF-ID |
Doctoral Thesis |
Agriculture |
| Velagapudi, Uday Kiran; Langelier, Marie-France; Delgado-Martin, Cristina; Diolaiti, Morgan E.; Bakker, Sietske et al. (2019). Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity. Journal of Medicinal Chemistry 62(11) , 5330-5357. 10.1021/acs.jmedchem.8b01709. [PDB: 6nrf, 6nrg, 6nrh, 6nri, 6nrj] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Smith, Bryan D.; Kaufman, Michael D.; Lu, Wei-Ping; Gupta, Anu; Leary, Cynthia B. et al. (2019). Ripretinib (DCC-2618) Is a Switch Control Kinase Inhibitor of a Broad Spectrum of Oncogenic and Drug-Resistant KIT and PDGFRA Variants. Cancer Cell 35(5) , 738-751.e9. 10.1016/j.ccell.2019.04.006. [PDB: 6mob] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Simonetta, K.R.; Clifton, M.C.; Walter, R.L.; Ranieri, G.M.; Lee, S.J. et al. (2019). Monophosphorylated pSer33 b-Catenin peptide, b-TrCP/Skp1, NRX-1933 ternary complex. Protein Data Bank: 6m93. |
CMCF-ID |
PDB Deposition |
Health |