| Ketcham, John M.; Harwood, Stephen J.; Aranda, Ruth; Aloiau, Athenea N.; Bobek, Briana M. et al. (2024). Discovery of Pyridopyrimidinones that Selectively Inhibit the H1047R PI3Kα Mutant Protein. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c00078. [PDB: 8v8h] |
CMCF-ID |
Peer-Reviewed Article |
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| Puumala, Emily; Sychantha, David; Lach, Elizabeth; Reeves, Shawn; Nabeela, Sunna et al. (2024). Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-β-thiophenylacrylamides exerts highly selective antifungal activity. Cell Chemical Biology . 10.1016/j.chembiol.2024.01.010. [PDB: 8uk6] |
CMCF-ID |
Peer-Reviewed Article |
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| Shurtleff, Valerie W.; Layton, Mark E.; Parish, Craig A.; Perkins, James J.; Schreier, John D. et al. (2024). Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.3c02248. [PDB: 8ute] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Folger, Ines B.; Frota, Natália F.; Pistofidis, Angelos; Niquille, David L.; Hansen, Douglas A. et al. (2024). High-throughput reprogramming of an NRPS condensation domain. Nature Chemical Biology . 10.1038/s41589-023-01532-x. [PDB: 8f7f] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| He, Liqi; Zhang, Meng Yao; Cox, Matthew; Zhang, Qian; Donnell, Andrew F. et al. (2024). Identification and Optimization of Small Molecule Pyrazolopyrimidine TLR7 Agonists for Applications in Immuno-oncology. ACS Medicinal Chemistry Letters 15(2) , 189-196. 10.1021/acsmedchemlett.3c00456. [PDB: 8s9h] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Boseley, Rhiannon E.; Sylvain, Nicole J.; Peeling, Lissa; Kelly, Michael E.; Pushie, M. Jake et al. (2024). A review of concepts and methods for FTIR imaging of biomarker changes in the post-stroke brain. Biochimica et Biophysica Acta - Biomembranes 1866(3) , 184287. 10.1016/j.bbamem.2024.184287. |
MID-IR |
Peer-Reviewed Article |
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| Daniel-Ivad, Phillip; Ryan, Katherine S. (2024). Structure of methyltransferase RedM that forms the dimethylpyrrolinium of the bisindole reductasporine. Journal of Biological Chemistry 300(1) , 105520. 10.1016/j.jbc.2023.105520. |
CMCF |
Peer-Reviewed Article |
Health |
| Daniel-Ivad, Phillip; Ryan, Katherine S. (2024). An imine reductase that captures reactive intermediates in the biosynthesis of the indolocarbazole reductasporine. Journal of Biological Chemistry , 105642. 10.1016/j.jbc.2024.105642. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Micuda, Ashley; Li, Hao; Rask‐Andersen, Helge; Ladak, Hanif M.; Agrawal, Sumit K. et al. (2024). Morphologic Analysis of the Scala Tympani Using Synchrotron: Implications for Cochlear Implantation. Laryngoscope . 10.1002/lary.31263. |
BMIT-ID |
Peer-Reviewed Article |
Health |
| Penner, Tiffany V.; Cobo, Neil Lorente; Patel, Deepak T.; Patel, Dhruvin H.; Savchenko, Alexei et al. (2023). Structural characterization of the Sel1‐like repeat protein LceB from Legionella pneumophila. Protein Science . 10.1002/pro.4889. [PDB: 8sxq] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Hao Li; Helge Eduard RASK-ANDERSEN; Dan JIang; Gerard Mary O’DONOGHUE; Douglas Edward Hugh HARTLEY et al. (2024). Method for the treatment of an auditory disease or condition. Patent Number: US20240074967A1. |
BMIT-ID |
Patent |
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| Gunn, R.J.; Lawson, J.D. (2024). PI3Ka H1047R co-crystal structure with inhibitor in cryptic pocket near H1047R (compound 4).. Protein Data Bank: 8v8h. |
CMCF-ID |
PDB Deposition |
Health |
| Hughes, M.P.; Taylor, J.P. (2024). Crystal Structure of the G3BP1 NTF2-like domain bound to the Caprin1 peptide. Protein Data Bank: 8th7. |
CMCF-ID |
PDB Deposition |
Health |
| Brooks, C.L.; Aguilar, E.N. (2024). Crystal Structure of the Humanized MUC16 Specific Antibody huAR9.6. Protein Data Bank: 8gkl. |
CMCF-ID |
PDB Deposition |
Health |
| Brooks, C.L.; Murray, B. (2024). Crystal Structure of the Humanized MUC16 Specific Antibody huAR9.6. Protein Data Bank: 8gkk. |
CMCF-ID |
PDB Deposition |
Health |