| Rahfeld, Peter; Sim, Lyann; Moon, Haisle; Constantinescu, Iren; Morgan-Lang, Connor et al. (2019). An enzymatic pathway in the human gut microbiome that converts A to universal O type blood. Nature Microbiology 4(9) . 10.1038/s41564-019-0469-7. [PDB: 6n1a] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Riggs, Jennifer R.; Elsner, Jan; Cashion, Dan; Robinson, Dale; Tehrani, Lida et al. (2019). Design and Optimization Leading to an Orally Active TTK Protein Kinase Inhibitor with Robust Single Agent Efficacy. Journal of Medicinal Chemistry 62(9) , 4401-4410. 10.1021/acs.jmedchem.8b01869. [PDB: 6n6o] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Sahtout, Naheda; Kuttiyatveetil, Jijin R.A.; Sanders, David A.R. (2019). Structure and function of the putative thioredoxin 1 from the thermophilic eubacterium Thermosipho africanus strain TCF52B. Biochimica et Biophysica Acta - Proteins and Proteomics 1867(4) , 426-433. 10.1016/j.bbapap.2019.01.011. [PDB: 6mos] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Smith, Bryan D.; Kaufman, Michael D.; Lu, Wei-Ping; Gupta, Anu; Leary, Cynthia B. et al. (2019). Ripretinib (DCC-2618) Is a Switch Control Kinase Inhibitor of a Broad Spectrum of Oncogenic and Drug-Resistant KIT and PDGFRA Variants. Cancer Cell 35(5) , 738-751.e9. 10.1016/j.ccell.2019.04.006. [PDB: 6mob] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Velagapudi, Uday Kiran; Langelier, Marie-France; Delgado-Martin, Cristina; Diolaiti, Morgan E.; Bakker, Sietske et al. (2019). Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity. Journal of Medicinal Chemistry 62(11) , 5330-5357. 10.1021/acs.jmedchem.8b01709. [PDB: 6nrf, 6nrg, 6nrh, 6nri, 6nrj] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Zhang, Birong; Kiefer, James R.; Blake, Robert A.; Chang, Jae H.; Hartman, Steven et al. (2019). Unexpected equivalent potency of a constrained chromene enantiomeric pair rationalized by co-crystal structures in complex with estrogen receptor alpha. Bioorganic and Medicinal Chemistry Letters 29(7) . 10.1016/j.bmcl.2019.01.036. [PDB: 6dfn] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Sachdev Sidhu; Linda Beatty; Andreas Ernst (2019). Specific active site inhibitors of enzymes or substrate binding partners and methods of producing same. Patent Number: US20190194270A1. |
CMCF-ID |
Patent |
Health |
| Antoshchenko, T.; Chen, Y.; Hughes, S.; Park, H. (2019). Crystal structure of ATPase domain of Human GRP78 bound to Ver155008. Protein Data Bank: 6cz1. |
CMCF-ID |
PDB Deposition |
Health |
| Brooks, C.L. (2019). Structure of VHH R419 isolated from a pre-immune phage display library. Protein Data Bank: 6dyx. |
CMCF-ID |
PDB Deposition |
Health |
| Fenalti, G. (2019). Crystal structure of the human TTK in complex with an inhibitor. Protein Data Bank: 6n6o. |
CMCF-ID |
PDB Deposition |
Health |
| Fischmann, T.O. (2019). Murine PI3K delta kinsae domain - cpd 1. Protein Data Bank: 6mul. |
CMCF-ID |
PDB Deposition |
Health |
| Garside, E.L.; MacMillan, A.M. (2019). Prp8 RH domain from C. merolae. Protein Data Bank: 6nqi. |
CMCF-ID |
PDB Deposition |
Health |
| Guarne, A.; Almawi, A.W. (2019). Crystal structure of the Escherichia coli sliding clamp-MutL complex.. Protein Data Bank: 6e8e. |
CMCF-ID |
PDB Deposition |
Health |
| Halgas, O.; Zarabi, S.F.; Schimmer, A.; Pai, E.F. (2019). Human mitochondrial ClpP in complex with ONC201 (TIC10). Protein Data Bank: 6dl7. |
CMCF-ID |
PDB Deposition |
Health |
| Kolesnikov, M.; Murphy, M.E.P. (2019). Crystal structure of Fusobacterium nucleatum flavodoxin mutant K13G bound to flavin mononucleotide. Protein Data Bank: 6ohk. |
CMCF-ID |
PDB Deposition |
Health |