Publication Beamlines Strategic Pillar
Blank, Matthew L.; Parker, Michelle L.; Ramaswamy, Raghavendran; Powell, Cameron J.; English, Elizabeth D. et al. (2018). A Toxoplasma gondii locus required for the direct manipulation of host mitochondria has maintained multiple ancestral functions. Molecular Microbiology 108(5) , 519-535. 10.1111/mmi.13947. [PDB: 6bxr, 6bxs] CMCF-BM, CMCF-ID Health
Gebai, Ahmad; Gorelik, Alexei; Li, Zixian; Illes, Katalin; Nagar, Bhushan et al. (2018). Structural basis for the activation of acid ceramidase. Nature Communications 9(1) . 10.1038/s41467-018-03844-2. [PDB: 5u7z, 5u81, 5u84] CMCF-BM, CMCF-ID Health
Jacques, Benoit; Coinçon, Mathieu; Sygusch, Jurgen (2018). Active site remodeling during the catalytic cycle in metal-dependent fructose-1,6-bisphosphate aldolases. Journal of Biological Chemistry 293(20) , 7737-7753. 10.1074/jbc.ra117.001098. [PDB: 5ucn, 5ucp, 5ucs, 5ucz, 5ud0, 5ud1, 5ud2] CMCF-BM, CMCF-ID Health
Labandera, Anne-Marie; Uhrig, R. Glen; Colville, Keaton; Moorhead, Greg B.; Ng, Kenneth K. S. et al. (2018). Structural basis for the preference of the Arabidopsis thaliana phosphatase RLPH2 for tyrosine-phosphorylated substrates. Science Signaling 11(524) , eaan8804. 10.1126/scisignal.aan8804. [PDB: 5vjv, 5vjw] CMCF-BM Health
Mellor, Paul; Marshall, Jeremy D. S.; Ruan, Xuan; Whitecross, Dielle E.; Ross, Rebecca L. et al. (2018). Patient-derived mutations within the N-terminal domains of p85α impact PTEN or Rab5 binding and regulation. Scientific Reports 8(1) . 10.1038/s41598-018-25487-5. [PDB: 6d81, 6d82, 6d85, 6d86, 6d87] CMCF-BM, CMCF-ID Health
Alexander, J.A.N.; Strynadka, N.C.J. (2018). Crystal structure of S. aureus penicillin binding protein 4 (PBP4) mutant (E183A, F241R) in complex with nafcillin. Protein Data Bank: 5ty2. CMCF-BM Health
Baral, P.K.; Swayampakula, M.; James, M.N.G. (2018). Structure of POM6 FAB fragment complexed with mouse PrPc. Protein Data Bank: 6aq7. CMCF-BM Health
Moore, S.A.; Marshall, J.D.; Anderson, D.H. (2018). Structure of the Bovine p85alpha BH domain, R262T mutant. Protein Data Bank: 6d87. CMCF-BM Health
Moore, S.A.; Marshall, J.D.; Anderson, D.H. (2018). Structure of the Bovine p85a BH domain. Protein Data Bank: 6d86. CMCF-BM Health
Moore, S.A.; Marshall, J.D.; Anderson, D.H. (2018). Structure of the Bovine p85a BH domain E217K mutant. Protein Data Bank: 6d85. CMCF-BM Health
Moore, S.A.; Marshall, J.D.; Anderson, D.H. (2018). Structure of the Bovine p85a BH domain. Protein Data Bank: 6d82. CMCF-BM Health
Bailey-Elkin; Ben (2018). Nidovirus papain-like proteases: structural insight into substrate recognition and innate immune suppression. Supervisor: Mark, Brian. Manitoba, Canada: University of Manitoba. http://hdl.handle.net/1993/32953. CMCF-BM, CMCF-ID Health
Verstraete; Meghan Marie (2018). SbnI is a free serine kinase and heme-sensing regulator required for staphyloferrin B biosynthesis in Staphylococcus aureus. Supervisor: Murphy, Michael. British Columbia, Canada: University of British Columbia. http://hdl.handle.net/2429/66404. CMCF-BM Health
Bagal, Sharan K.; Andrews, Mark; Bechle, Bruce M.; Bian, Jianwei; Bilsland, James et al. (2018). Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of Pain. Journal of Medicinal Chemistry 61(15) , 6779-6800. 10.1021/acs.jmedchem.8b00633. [PDB: 6dkb] CMCF-ID Health
Bagal, Sharan K.; Omoto, Kiyoyuki; Blakemore, David C.; Bungay, Peter J.; Bilsland, James G. et al. (2018). Discovery of Allosteric, Potent, Subtype Selective, and Peripherally Restricted TrkA Kinase Inhibitors. Journal of Medicinal Chemistry 62(1) , 247-265. 10.1021/acs.jmedchem.8b00280. [PDB: 6d20] CMCF-ID Health