Publication Beamlines Strategic Pillar
Mabanglo, M.F.; Wilson, B.J.; Krausser, C.; Hoffer, L.; Al-awar, R. et al. (2024). Crystal structure of the ternary complex of DCAF1 and WDR5 with PROTAC, OICR-40407. Protein Data Bank: 9b9t. CMCF-BM Health
Mabanglo, M.F.; Wilson, B.J.; Alvarez, H.G.; Hoffer, L.; Al-awar, R. et al. (2024). Crystal structure of the ternary complex of DCAF1 and WDR5 with PROTAC, OICR-40333. Protein Data Bank: 9b9h. CMCF-BM Health
Mabanglo, Mark F.; Wilson, Brian; Noureldin, Mahmoud; Kimani, Serah W.; Mamai, Ahmed et al. (2024). Crystal structures of DCAF1-PROTAC-WDR5 ternary complexes provide insight into DCAF1 substrate specificity. Nature Communications 15(1) . 10.1038/s41467-024-54500-x. [PDB: 9b9h, 9b9t, 9b9w, 9ba2] CMCF-BM Health
Langelier, Marie-France; Mirhasan, Manija; Gilbert, Karine; Sverzhinksy, Aleksandr; Furtos, Alexandra et al. (2024). PARP enzyme de novo synthesis of protein-free poly(ADP-ribose). Molecular Cell 84(24) , 4758-4773.e6. 10.1016/j.molcel.2024.10.024. [PDB: 9bpy, 9dmc] CMCF-BM Health
Kimani, S.; Dong, A.; Li, Y.; Seitova, A.; Al-awar, R. et al. (2024). Crystal structure of the human DCAF1 WDR domain in complex with OICR-41103. Protein Data Bank: 9d4e. CMCF-BM Health
Harris, S.F.; Wu, P. (2024). Mtb GuaB dCBS in complex with inhibitor compound 5. Protein Data Bank: 9dc9. CMCF-BM Health
Harris, S.F.; Wu, P. (2024). Mtb GuaB dCBS in complex with inhibitor G1. Protein Data Bank: 9dc8. CMCF-BM Health
Cho, Timothy HS (2024). Mechanisms of Sensory Signal Transduction Across the Envelope in the CpxRA System of Escherichia coli. Supervisor: Raivio, Tracy. Alberta, Canada: University of Alberta. https://doi.org/10.7939/r3-kpc4-mn64. CMCF-BM Health
Worrall, L.J.; Strynadka, N.C.J. (2024). Structure of the A type blood alpha-D-galactosamine galactosaminidase D463A mutant from Flavonifractor plautii. Protein Data Bank: 9ayu. CMCF-ID Health
Vu, Binh T.; Dominique, Romyr; Fahr, Bruce J.; Li, Hongju H.; Fry, David C. et al. (2024). Discovery of Rezatapopt (PC14586), a First-in-Class, Small-Molecule Reactivator of p53 Y220C Mutant in Development. ACS Medicinal Chemistry Letters . 10.1021/acsmedchemlett.4c00379. [PDB: 9br4] CMCF-ID Health
Thai, Elaine (2024). Molecular Characterization of Monoclonal Antibodies Against Malaria Antigen Circumsporozoite Protein to Guide the Design of Antibody-Based Interventions. Supervisor: Julien, Jean-Philippe. Ontario, Canada: University of Toronto. http://hdl.handle.net/1807/140551. CMCF-ID Health
Poullennec, Karine G.; Jnoff, Eric; Abendroth, Jan; Bhuma, Naresh; Calmiano, Mark et al. (2024). Discovery of UCB9386: A Potent, Selective, and Brain-Penetrant Nuak1 Inhibitor Suitable for In Vivo Pharmacological Studies. Journal of Medicinal Chemistry 67(23) , 20879-20910. 10.1021/acs.jmedchem.4c01237. [PDB: 8uoj] CMCF-ID Health
Pistofidis, A.; Schmeing, T.M. (2024). The post-condensation state of the dimodular NRPS protein LgrA. Protein Data Bank: 9be4. CMCF-ID Health
Pistofidis, A.; Schmeing, T.M. (2024). The pre-condensation state of the dimodular NRPS protein LgrA. Protein Data Bank: 9be3. CMCF-ID Health
Ide, Danilo; Gorelik, Alexei; Illes, Katalin; Nagar, Bhushan (2024). Structural Analysis of Mammalian Sialic Acid Esterase. Journal of Molecular Biology 436(22) , 168801. 10.1016/j.jmb.2024.168801. [PDB: 8f9o] CMCF-ID Health