| Rathinaswamy, Manoj K; Gaieb, Zied; Fleming, Kaelin D; Borsari, Chiara; Harris, Noah J et al. (2021). Disease-related mutations in PI3Kγ disrupt regulatory C-terminal dynamics and reveal a path to selective inhibitors. eLife 10. 10.7554/elife.64691. [PDB: 7jwe, 7jwz, 7jx0] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Scholl, Connor L.; Tsuda, Sakae; Graham, Laurie A.; Davies, Peter L. (2021). Crystal waters on the nine polyproline type II helical bundle springtail antifreeze protein from
Granisotoma rainieri
match the ice lattice. FEBS Journal 288(14) . 10.1111/febs.15717. [PDB: 7jjv] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Shah, Megha; Taylor, Véronique L.; Bona, Diane; Tsao, Yvonne; Stanley, Sabrina Y. et al. (2021). A phage-encoded anti-activator inhibits quorum sensing in Pseudomonas aeruginosa. Molecular Cell 81(3) , 571-583.e6. 10.1016/j.molcel.2020.12.011. [PDB: 6v7u, 6v7v] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Vatta, Maritza; Lyons, Bronwyn; Heney, Kayla A.; Lidster, Taylor; Merrill, A. Rod et al. (2021). Mapping the DNA-Binding Motif of Scabin Toxin, a Guanine Modifying Enzyme from Streptomyces scabies. Toxins 13(1) , 55. 10.3390/toxins13010055. [PDB: 6vuv, 6vv4, 6vvf] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Shuaiqi GUO; Ilja VOETS; Peter Davies; Karl Klose (2021). Peptides for use in the treatment of cholera. Patent Number: WO2021010835A1. |
CMCF-ID |
Patent |
Health |
| Burke, J.E.; Rathinaswamy, M.K.; Harris, N.J. (2021). Gedatolisib bound to the PI3Kg catalytic subunit p110 gamma. Protein Data Bank: 7jwe. |
CMCF-ID |
PDB Deposition |
Health |
| Burke, J.E.; Rathinaswamy, M.K.; Harris, N.J. (2021). NVS-PI3-4 bound to the PI3Kg catalytic subunit p110 gamma. Protein Data Bank: 7jx0. |
CMCF-ID |
PDB Deposition |
Health |
| Burke, J.E.; Rathinaswamy, M.K.; Harris, N.J. (2021). IPI-549 bound to the PI3Kg catalytic subunit p110 gamma. Protein Data Bank: 7jwz. |
CMCF-ID |
PDB Deposition |
Health |
| Chen, S.; Lu, M. (2021). Arsenic-bound p53 DNA-binding domain mutant R249S. Protein Data Bank: 7dhz. |
CMCF-ID |
PDB Deposition |
Health |
| Cygler, M.; Chung, I.Y.W. (2021). Structure of RavA (lpp0008) E38A/K39A surface entropy reduction mutant. Protein Data Bank: 6wo6. |
CMCF-ID |
PDB Deposition |
Health |
| Heney, K.; Lyons, B.; Merrill, A.R. (2021). Scabin (Y129H) toxin from Streptomyces scabies. Protein Data Bank: 6vvf. |
CMCF-ID |
PDB Deposition |
Health |
| Heney, K.; Lyons, B.; Merrill, A.R. (2021). Scabin (V109G) toxin from Streptomyces scabies. Protein Data Bank: 6vv4. |
CMCF-ID |
PDB Deposition |
Health |
| Liang, J.; Naineni, S.K.; Pelletier, J.; Nagar, B. (2021). Crystal structure of eIF4A-I in complex with RNA bound to des-MePateA, a pateamine A analog. Protein Data Bank: 6xki. |
CMCF-ID |
PDB Deposition |
Health |
| Lyons, B.; Lidster, T.; Merrill, A.R. (2021). Scabin (S117A) toxin from Streptomyces scabies. Protein Data Bank: 6vuv. |
CMCF-ID |
PDB Deposition |
Health |
| Murray, J.M. (2021). BRD4-BD1 Compound6 (methyl 4-(3,5-difluoropyridin-2-yl)-10-methyl-7-((methylsulfonyl)methyl)-11-oxo-3,4,10,11-tetrahydro-1H-1,4,10-triazadibenzo[cd,f]azulene-6-carboxylate). Protein Data Bank: 7khl. |
CMCF-ID |
PDB Deposition |
Health |