| Ndubaku, Chudi O.; Crawford, James J.; Drobnick, Joy; Aliagas, Ignacio; Campbell, David et al. (2015). Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-pKa Polar Moiety. ACS Medicinal Chemistry Letters 6(12) , 1241-1246. 10.1021/acsmedchemlett.5b00398. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Heald, Robert; Bowman, Krista K.; Bryan, Marian C.; Burdick, Daniel; Chan, Bryan et al. (2015). Noncovalent Mutant Selective Epidermal Growth Factor Receptor Inhibitors: A Lead Optimization Case Study. Journal of Medicinal Chemistry 58(22) , 8877-8895. 10.1021/acs.jmedchem.5b01412. [PDB: 5cal, 5cao, 5cap] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Gregg, Katie J.; Suits, Michael D.L.; Deng, Lehua; Vocadlo, David J.; Boraston, Alisdair B. et al. (2015). Structural Analysis of a Family 101 Glycoside Hydrolase in Complex with Carbohydrates Reveals Insights into Its Mechanism. Journal of Biological Chemistry 290(42) , 25657-25669. 10.1074/jbc.m115.680470. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Concha, Nestor O.; Smallwood, Angela; Bonnette, William; Totoritis, Rachel; Zhang, Guofeng et al. (2015). Long-Range Inhibitor-Induced Conformational Regulation of Human IRE1αEndoribonuclease Activity. Molecular Pharmacology 88(6) , 1011-1023. 10.1124/mol.115.100917. [PDB: 4yzd] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Blackler, Ryan J; Evans, Dylan W; Smith, David F; Cummings, Richard D; Brooks, Cory L et al. (2015). Single-chain antibody-fragment M6P-1 possesses a mannose 6-phosphate monosaccharide-specific binding pocket that distinguishesN-glycan phosphorylation in a branch-specific manner. Glycobiology 26(2) , 181-192. 10.1093/glycob/cwv093. [PDB: 4rzc] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Baker, Perrin; Whitfield, Gregory B.; Hill, Preston J.; Little, Dustin J.; Pestrak, Matthew J. et al. (2015). Characterization of the Pseudomonas aeruginosa Glycoside Hydrolase PslG Reveals That Its Levels Are Critical for Psl Polysaccharide Biosynthesis and Biofilm Formation. Journal of Biological Chemistry 290(47) , 28374-28387. 10.1074/jbc.m115.674929. [PDB: 5bxa] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Alaidi; Osama (2015). Structural characterization of Gemini-based nanoparticles for delivery of DNA. Supervisor: Grochulski, Pawel; Badea, Ildiko. Saskatchewan: University of Saskatchewan. http://hdl.handle.net/10388/ETD-2014-05-1619. |
CMCF-BM, CMCF-ID |
Masters Thesis |
Health |
| Whittington, D.A.; Tang, J.; Yakowec, P. (2015). Crystal structure of human PI3K-gamma in complex with benzimidazole inhibitor 5. Protein Data Bank: 5eds. |
CMCF-ID |
PDB Deposition |
Health |
| Scapin, G.; Prosise, W.; Reichert, P. (2015). Crystal Structure of Pembrolizumab, a full length IgG4 antibody. Protein Data Bank: 5dk3. |
CMCF-ID |
PDB Deposition |
Health |
| Sack, J.S. (2015). CRYSTAL STRUCTURE OF MICROTUBULE AFFINITY-REGULATING KINASE 4 CATALYTIC DOMAIN IN COMPLEX WITH A PYRAZOLOPYRIMIDINE INHIBITOR. Protein Data Bank: 5es1. |
CMCF-ID |
PDB Deposition |
Health |
| Ravulapalli, R.; Tempel, W.; Merrrill, A.R. (2015). Vis toxin, an ADP-ribosyltransferase from Vibrio Splendidus. Protein Data Bank: 4y1w. |
CMCF-ID |
PDB Deposition |
Health |
| Ravulapalli, R.; Merrill, A.R. (2015). Crystal structure of ADP-ribosyltransferase Vis in complex with M6 Inhibitor. Protein Data Bank: 4yc0. |
CMCF-ID |
PDB Deposition |
Health |
| Parker, M.L.; Boulanger, M.J. (2015). Crystal structure of AMA4 DI-DII-EGF1 from Toxoplasma gondii. Protein Data Bank: 4z81. |
CMCF-ID |
PDB Deposition |
Health |
| Parker, M.L.; Boulanger, M.J. (2015). Crystal structure of Toxoplasma gondii AMA4 DI-DII-EGF1 in complex with a 33 aa TgRON2L1 peptide. Protein Data Bank: 4z80. |
CMCF-ID |
PDB Deposition |
Health |
| Klein, D.J.; Patel, S. (2015). Crystal Structure of the Prototype Foamy Virus Intasome with a 2-Pyridinone Aminal Inhibitor. Protein Data Bank: 4ztf. |
CMCF-ID |
PDB Deposition |
Health |