Publication Beamlines Strategic Pillar
Seattle Structural Genomics Center for Infectious Disease (SSGCID) (2022). Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-1235 (enantiomer). Protein Data Bank: 5sd1. CMCF-ID Health
Seattle Structural Genomics Center for Infectious Disease (SSGCID) (2022). Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-1225. Protein Data Bank: 5sd0. CMCF-ID Health
Seattle Structural Genomics Center for Infectious Disease (SSGCID) (2022). Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-1224. Protein Data Bank: 5scz. CMCF-ID Health
Fortinez, C.M.; Sharon, I.; Schmeing, T.M. (2022). Crystal structure of the elongation module of the bacillamide NRPS, BmdB, in complex with the oxidase BmdC. Protein Data Bank: 7ly7. CMCF-ID Health
Fortinez, C.M.; Bloudoff, K.; Schmeing, T.M. (2022). Structure of a trans-acting NRPS oxidase, BmdC, involved in bacillamide biosynthesis. Protein Data Bank: 7ly6. CMCF-ID Health
Palte, R.L. (2022). Structure of CHK1 10-pt. mutant complex with LRRK2 inhibitor 15. Protein Data Bank: 7suh. CMCF-ID Health
Vajdos, F.F. (2022). Vanin-1 complexed with Compound 27. Protein Data Bank: 7sly. CMCF-ID Health
Saran, S.; Sanders, D.A.R. (2022). Dihydrodipicolinate synthase (DHDPS) from C.jejuni, with pyruvate bound in the active site and L-lysine bound at the allosteric site in C121 space group. Protein Data Bank: 7lcf. CMCF-ID Health
Saran, S.; Yazdi, M.M.; Sanders, D.A.R. (2022). Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H59K mutant with pyruvate bound in the active site in C2221 space group. Protein Data Bank: 7lbd. CMCF-ID Health
Fedoretz-Maxwell, Brooklyn P.; Shin, Catherine H.; MacNeil, Gregory A.; Worrall, Liam J.; Park, Rachel et al. (2022). The Impact of Second Coordination Sphere Methionine-Aromatic Interactions in Copper Proteins. Inorganic Chemistry 61(14) , 5563-5571. 10.1021/acs.inorgchem.2c00030. [PDB: 7tc5] CMCF-BM, CMCF-ID Health
Lu, Jimmy; Chen, Sizhu Amelia; Khan, Muhammad Bashir; Brassard, Raelynn; Arutyunova, Elena et al. (2022). Crystallization of Feline Coronavirus Mpro With GC376 Reveals Mechanism of Inhibition. Frontiers in Chemistry 10. 10.3389/fchem.2022.852210. [PDB: 7smv, 7sna] CMCF-BM Health
Li, Mingzong; Konteatis, Zenon; Nagaraja, Nelamangala; Chen, Yue; Zhou, Shubao et al. (2022). Leveraging Structure-Based Drug Design to Identify Next-Generation MAT2A Inhibitors, Including Brain-Penetrant and Peripherally Efficacious Leads. Journal of Medicinal Chemistry 65(6) , 4600-4615. 10.1021/acs.jmedchem.1c01595. [PDB: 7rwg] CMCF-BM Health
Vergunst, Kathleen L.; Langelaan, David N. (2022). The N-terminal tail of the hydrophobin SC16 is not required for rodlet formation. Scientific Reports 12(1) . 10.1038/s41598-021-04223-6. CMCF-BM Health
Sharon, Itai; Grogg, Marcel; Hilvert, Donald; Schmeing, T. Martin (2022). Structure and Function of the β-Asp-Arg Polymerase Cyanophycin Synthetase 2. ACS Chemical Biology 17(3) . 10.1021/acschembio.1c01007. [PDB: 7ta5] CMCF-BM Health
Shen, Yao; Gomez-Blanco, Josue; Petassi, Michael T.; Peters, Joseph E.; Ortega, Joaquin et al. (2022). Structural basis for DNA targeting by the Tn7 transposon. Nature Structural and Molecular Biology 29(2) , 143-151. 10.1038/s41594-022-00724-8. [PDB: 7mbw] CMCF-BM Health