Cottrell, Kevin M.; Briggs, Kimberly J.; Whittington, Douglas A.; Jahic, Haris; Ali, Janid A. et al. (2024). Discovery of TNG908: A Selective, Brain Penetrant, MTA-Cooperative PRMT5 Inhibitor That Is Synthetically Lethal with MTAP-Deleted Cancers. Journal of Medicinal Chemistry 67(8) , 6064-6080. 10.1021/acs.jmedchem.4c00133. [PDB: 8veu] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Cummer, Rebecca; Grosjean, Félix; Bolteau, Raphaël; Vasegh, Seyed Ehsan; Veyron, Simon et al. (2024). Structure-activity relationship of inositol thiophosphate analogs as allosteric activators of Clostridioides difficile toxin B. Applied Spectroscopy Reviews . 10.26434/chemrxiv-2024-2cf6g-v2. [PDB: 9bja] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Xu, Shangyi; Grochulski, Pawel; Tanaka, Takuji (2024). Structural basis for the allosteric behaviour and substrate specificity of Lactococcus lactis Prolidase. Biochimica et Biophysica Acta - Proteins and Proteomics 1872(3) , 141000. 10.1016/j.bbapap.2024.141000. |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
Ali, M.G.H.; Wahba, H.M.; Cyr, N.; Omichinski, J.G. (2024). Crystal structure of K46 acetylated GABARAP in complex with the LIR of TP53INP2/DOR. Protein Data Bank: 8t33. |
CMCF-BM |
PDB Deposition |
Health |
Bon, C.G.; Lee, J.; Caveney, N.A.; Strynadka, N.C.J. (2024). Structure of the monofunctional Staphylococcus aureus PBP1 in its beta-lactam (Ertapenem) inhibited form. Protein Data Bank: 8vbw. |
CMCF-BM |
PDB Deposition |
Health |
Bon, C.G.; Lee, J.; Caveney, N.A.; Strynadka, N.C.J. (2024). Structure of the monofunctional Staphylococcus aureus PBP1 in its beta-lactam (Cephalexin) inhibited form. Protein Data Bank: 8vbv. |
CMCF-BM |
PDB Deposition |
Health |
Bon, C.G.; Lee, J.; Caveney, N.A.; Strynadka, N.C.J. (2024). Structure of the monofunctional Staphylococcus aureus PBP1 in its apo form. Protein Data Bank: 8vbt. |
CMCF-BM |
PDB Deposition |
Health |
Chi, C.B.; Liang, Z.D.; Huo, B.Q.; Hu, C.X.; Sun, Q.Y. et al. (2024). Crystal structure of estZF172 as a novel biocatalyst for the efficient biosynthesis of a chiral intermediate of pregabalin. Protein Data Bank: 8j5v. |
CMCF-BM |
PDB Deposition |
Health |
Lazarski, A.C.; Worrall, L.J.; Strynadka, N.C.J. (2024). Structure of Alistipes sp. 3-Keto-2-hydroxy-glucal-hydratase AL2. Protein Data Bank: 8v31. |
CMCF-BM |
PDB Deposition |
Health |
Lazarski, A.C.; Worrall, L.J.; Strynadka, N.C.J. (2024). Structure of P2B11 Glucuronide-3-dehydrogenase. Protein Data Bank: 8tdi. |
CMCF-BM |
PDB Deposition |
Health |
Lazarski, A.C.; Worrall, L.J.; Strynadka, N.C.J. (2024). Structure of glucose bound Bacteroides thetaiotaomicron 3-Keto-2-hydroxy-glucal-hydratase BT2. Protein Data Bank: 8tde. |
CMCF-BM |
PDB Deposition |
Health |
Lazarski, A.C.; Worrall, L.J.; Strynadka, N.C.J. (2024). Structure of Bacteroides thetaiotaomicron 3-Keto-2-hydroxy-glucal-hydratase BT2. Protein Data Bank: 8tda. |
CMCF-BM |
PDB Deposition |
Health |
Lazarski, A.C.; Worrall, L.J.; Strynadka, N.C.J. (2024). Structure of 3K-GlcH bound Bacteroides thetaiotaomicron 3-Keto-beta-glucopyranoside-1,2-Lyase BT1. Protein Data Bank: 8tct. |
CMCF-BM |
PDB Deposition |
Health |
Lazarski, A.C.; Worrall, L.J.; Strynadka, N.C.J. (2024). Structure of glucose bound Alistipes sp. 3-Keto-beta-glucopyranoside-1,2-Lyase AL1. Protein Data Bank: 8tcr. |
CMCF-BM |
PDB Deposition |
Health |
Lazarski, A.C.; Worrall, L.J.; Strynadka, N.C.J. (2024). Structure of Alistipes sp. 3-Keto-beta-glucopyranoside-1,2-Lyase AL1. Protein Data Bank: 8tcd. |
CMCF-BM |
PDB Deposition |
Health |