| Sintchak, M.; Lane, W.; Bump, N. (2021). Structure of SUMO1-ML786519 adduct bound to SAE. Protein Data Bank: 6xog. |
CMCF-ID |
PDB Deposition |
Health |
| Chen, S.; Lu, M. (2021). Arsenic-bound p53 DNA-binding domain mutant R249S. Protein Data Bank: 7dhz. |
CMCF-ID |
PDB Deposition |
Health |
| Murray, J.M. (2021). BRD4-BD1 Compound6 (methyl 4-(3,5-difluoropyridin-2-yl)-10-methyl-7-((methylsulfonyl)methyl)-11-oxo-3,4,10,11-tetrahydro-1H-1,4,10-triazadibenzo[cd,f]azulene-6-carboxylate). Protein Data Bank: 7khl. |
CMCF-ID |
PDB Deposition |
Health |
| Lyons, B.; Lidster, T.; Merrill, A.R. (2021). Scabin (S117A) toxin from Streptomyces scabies. Protein Data Bank: 6vuv. |
CMCF-ID |
PDB Deposition |
Health |
| Heney, K.; Lyons, B.; Merrill, A.R. (2021). Scabin (Y129H) toxin from Streptomyces scabies. Protein Data Bank: 6vvf. |
CMCF-ID |
PDB Deposition |
Health |
| Heney, K.; Lyons, B.; Merrill, A.R. (2021). Scabin (V109G) toxin from Streptomyces scabies. Protein Data Bank: 6vv4. |
CMCF-ID |
PDB Deposition |
Health |
| Liang, J.; Naineni, S.K.; Pelletier, J.; Nagar, B. (2021). Crystal structure of eIF4A-I in complex with RNA bound to des-MePateA, a pateamine A analog. Protein Data Bank: 6xki. |
CMCF-ID |
PDB Deposition |
Health |
| Shuaiqi GUO; Ilja VOETS; Peter Davies; Karl Klose (2021). Peptides for use in the treatment of cholera. Patent Number: WO2021010835A1. |
CMCF-ID |
Patent |
Health |
| Shah, Megha; Taylor, Véronique L.; Bona, Diane; Tsao, Yvonne; Stanley, Sabrina Y. et al. (2021). A phage-encoded anti-activator inhibits quorum sensing in Pseudomonas aeruginosa. Molecular Cell 81(3) , 571-583.e6. 10.1016/j.molcel.2020.12.011. [PDB: 6v7u, 6v7v] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Beshore, Douglas C.; Adam, Gregory C.; Barnard, Richard J. O.; Burlein, Christine; Gallicchio, Steven N. et al. (2021). Redefining the Histone Deacetylase Inhibitor Pharmacophore: High Potency with No Zinc Cofactor Interaction. ACS Medicinal Chemistry Letters 12(4) , 540-547. 10.1021/acsmedchemlett.1c00074. [PDB: 7ltg] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Quiroz, Ryan V.; Reutershan, Michael H.; Schneider, Sebastian E.; Sloman, David; Lacey, Brian M. et al. (2021). The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer. Journal of Medicinal Chemistry 64(7) , 3911-3939. 10.1021/acs.jmedchem.0c02083. [PDB: 7kib] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Higgins, Melanie A.; Tegl, Gregor; MacDonald, Spencer S.; Arnal, Gregory; Brumer, Harry et al. (2021). N-Glycan Degradation Pathways in Gut- and Soil-Dwelling Actinobacteria Share Common Core Genes. ACS Chemical Biology 16(4) . 10.1021/acschembio.0c00995. [PDB: 7lqx, 7lr1] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Davies, Christopher W.; Stowe, Irma; Phung, Qui T.; Ho, Hoangdung; Bakalarski, Corey E. et al. (2021). Discovery of a caspase cleavage motif antibody reveals insights into noncanonical inflammasome function. Proceedings of the National Academy of Sciences of the United States of America 118(12) , e2018024118. 10.1073/pnas.2018024118. [PDB: 7jwq] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Mulligan, Vikram Khipple; Workman, Sean; Sun, Tianjun; Rettie, Stephen; Li, Xinting et al. (2021). Computationally designed peptide macrocycle inhibitors of New Delhi metallo-β-lactamase 1. Proceedings of the National Academy of Sciences of the United States of America 118(12) , e2012800118. 10.1073/pnas.2012800118. [PDB: 6xbe, 6xbf] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Rathinaswamy, Manoj K; Gaieb, Zied; Fleming, Kaelin D; Borsari, Chiara; Harris, Noah J et al. (2021). Disease-related mutations in PI3Kγ disrupt regulatory C-terminal dynamics and reveal a path to selective inhibitors. eLife 10. 10.7554/elife.64691. [PDB: 7jwe, 7jwz, 7jx0] |
CMCF-ID |
Peer-Reviewed Article |
Health |