Palte, R.L.; Schneider, S.E. (2020). PRMT5:MEP50 Complexed with Allosteric Inhibitor Compound 8. Protein Data Bank: 6uxy. |
CMCF-ID |
PDB Deposition |
Health |
Palte, Rachel L.; Schneider, Sebastian E.; Altman, Michael D.; Hayes, Robert P.; Kawamura, Shuhei et al. (2020). Allosteric Modulation of Protein Arginine Methyltransferase 5 (PRMT5). ACS Medicinal Chemistry Letters 11(9) . 10.1021/acsmedchemlett.9b00525. [PDB: 6uxy] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Wang, F.; Lin, D.; Cheng, W.; Bao, X.; Zhu, B. et al. (2020). The Crystal Structure of human LDHA from Wuxi Biortus.. Protein Data Bank: 6zzr. |
CMCF-ID |
PDB Deposition |
Health |
Parthasarathy, G.; Soisson, S.M. (2020). Sortilin-Progranulin Interaction With Compound 17. Protein Data Bank: 6x48. |
CMCF-ID |
PDB Deposition |
Health |
Parthasarathy, G.; Soisson, S.M. (2020). Sortilin-Progranulin Interaction With Compound 2. Protein Data Bank: 6x3l. |
CMCF-ID |
PDB Deposition |
Health |
Stachel, Shawn J.; Ginnetti, Anthony T.; Johnson, Scott A.; Cramer, Paige; Wang, Yi et al. (2020). Identification of potent inhibitors of the sortilin-progranulin interaction. Bioorganic and Medicinal Chemistry Letters 30(17) , 127403. 10.1016/j.bmcl.2020.127403. [PDB: 6x3l, 6x48] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Gorelik, A.; Labriola, J.M.; Illes, K.; Nagar, B. (2020). Human ectonucleoside triphosphate diphosphohydrolase 4 (ENTPD4, NTPDase 4). Protein Data Bank: 6wg5. |
CMCF-ID |
PDB Deposition |
Health |
Chung, C. (2020). PROTAC6 mediated complex of VHL:EloB:EloC and Bcl-xL. Protein Data Bank: 6zhc. |
CMCF-ID |
PDB Deposition |
Health |
Chung, Chun-wa; Dai, Han; Fernandez, Esther; Tinworth, Christopher P.; Churcher, Ian et al. (2020). Structural Insights into PROTAC-Mediated Degradation of Bcl-xL. ACS Chemical Biology 15(9) . 10.1021/acschembio.0c00266. [PDB: 6zhc] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Thai, E.; Scally, S.W.; Julien, J.P. (2020). Crystal structure of antibody 5D5 in complex with PfCSP N-terminal peptide. Protein Data Bank: 6uud. |
CMCF-ID |
PDB Deposition |
Health |
Thai, E.; Scally, S.W.; Prieto, K.; Murugan, R.; Wardemann, H. et al. (2020). Crystal structure of 4498 Fab in complex with circumsporozoite protein NDN3 and anti-Kappa VHH domain. Protein Data Bank: 6ulf. |
CMCF-ID |
PDB Deposition |
Health |
Murugan, Rajagopal; Scally, Stephen W.; Costa, Giulia; Mustafa, Ghulam; Thai, Elaine et al. (2020). Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs. Nature Medicine 26(7) . 10.1038/s41591-020-0881-9. [PDB: 6ulf] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Sack, J.S. (2020). SUBSTITUTED BENZYLOXYTRICYCLIC COMPOUNDS AS RETINOIC ACID-RELATED ORPHAN RECEPTOR GAMMA T AGONISTS. Protein Data Bank: 6xae. |
CMCF-ID |
PDB Deposition |
Health |
Harikrishnan, Lalgudi S.; Gill, Patrice; Kamau, Muthoni G.; Qin, Lan-Ying; Ruan, Zheming et al. (2020). Substituted benzyloxytricyclic compounds as retinoic acid-related orphan receptor gamma t (RORγt) agonists. Bioorganic and Medicinal Chemistry Letters 30(12) , 127204. 10.1016/j.bmcl.2020.127204. [PDB: 6xae] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Dong, Cheng; Chen, Shun-Jia; Melnykov, Artem; Weirich, Sara; Sun, Kelly et al. (2020). Recognition of nonproline N-terminal residues by the Pro/N-degron pathway. Proceedings of the National Academy of Sciences of the United States of America 117(25) , 14158-14167. 10.1073/pnas.2007085117. [PDB: 6wzz] |
CMCF-ID |
Peer-Reviewed Article |
Health |