| Saran, S.; Majdi Yazdi, M.; Sanders, D.A.R. (2021). Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H59K mutant with pyruvate bound in the active site and L-histidine bound at the allosteric site. Protein Data Bank: 7kg2. |
CMCF-ID |
PDB Deposition |
Health |
| Murray, B.W.; Rogers, E.; Zhai, D.; Deng, W.; Chen, X. et al. (2021). Crystal structure of TrkA kinase with repotrectinib. Protein Data Bank: 7vko. |
CMCF-ID |
PDB Deposition |
Health |
| Ereno-Orbea, J.; Nilvebrant, J.; Sidhu, S.; Julien, J.P. (2021). Anti-EphA1 JD1 VH domain. Protein Data Bank: 7ooi. |
CMCF-ID |
PDB Deposition |
Health |
| Nilvebrant, Johan; Ereño-Orbea, June; Gorelik, Maryna; Julian, Mark C.; Tessier, Peter M. et al. (2021). Systematic Engineering of Optimized Autonomous Heavy-Chain Variable Domains. Journal of Molecular Biology 433(21) , 167241. 10.1016/j.jmb.2021.167241. [PDB: 7ooi] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Saran, S.; Sanders, D.A.R. (2021). Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H59K mutant with pyruvate bound in the active site. Protein Data Bank: 7kel. |
CMCF-ID |
PDB Deposition |
Health |
| Sahtout, N.; Kuttiyatveetil, J.R.A.; Sanders, D.A.R. (2021). Structure of thioredoxin reductase from the thermophilic eubacterium Thermosipho africanus TCF52B. Protein Data Bank: 7jyp. |
CMCF-ID |
PDB Deposition |
Health |
| Mao, Z.W.; Xia, W.; Tao, X. (2021). The crystal structure of SARS-CoV-2 3CLpro with Zinc. Protein Data Bank: 7d64. |
CMCF-BM, CMCF-ID |
PDB Deposition |
Health |
| Sheriff, S. (2021). CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH BMS-986158, 2-{3-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-5-[(S)-(oxan-4-yl)(phenyl)methyl]-5H-pyrido[3,2-b]indol-7-yl}propan-2-ol. Protein Data Bank: 5s9r. |
CMCF-ID |
PDB Deposition |
Health |
| Gavai, Ashvinikumar V.; Norris, Derek; Delucca, George; Tortolani, David; Tokarski, John S. et al. (2021). Discovery and Preclinical Pharmacology of an Oral Bromodomain and Extra-Terminal (BET) Inhibitor Using Scaffold-Hopping and Structure-Guided Drug Design. Journal of Medicinal Chemistry 64(19) . 10.1021/acs.jmedchem.1c00625. [PDB: 5s9r] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Sheriff, S. (2021). CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH 2-{(7P)-7-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-8-fluoro-5-[(S)-(oxan-4-yl)(phenyl)methyl]-5H-pyrido[3,2-b]indol-3-yl}propan-2-ol. Protein Data Bank: 7mce. |
CMCF-ID |
PDB Deposition |
Health |
| Hill, Matthew D.; Quesnelle, Claude; Tokarski, John; Fang, Haiquan; Fanslau, Carolynn et al. (2021). Development of BET inhibitors as potential treatments for cancer: A new carboline chemotype. Bioorganic and Medicinal Chemistry Letters 51, 128376. 10.1016/j.bmcl.2021.128376. [PDB: 7mce] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Maben, Z.; Liu, W.; Mosyak, L.; Chaparro-Riggers, J. (2021). Crystal structure of the CD27:CD70 co-stimulatory complex. Protein Data Bank: 7kx0. |
CMCF-ID |
PDB Deposition |
Health |
| Liu, Weifeng; Maben, Zachary; Wang, Carole; Lindquist, Kevin C.; Li, Manqing et al. (2021). Structural delineation and phase-dependent activation of the costimulatory CD27:CD70 complex. Journal of Biological Chemistry 297(4) , 101102. 10.1016/j.jbc.2021.101102. [PDB: 7kx0] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Guo, Y.; Dong, A.; Hou, F.; Li, Y.; Zhang, W. et al. (2021). Crystal structure of STAMBPL1 in complex with an engineered binder. Protein Data Bank: 7l97. |
CMCF-ID |
PDB Deposition |
Health |
| Workman, Sean D.; Day, Jonathan; Farha, Maya A.; El Zahed, Sara S.; Bon, Chris et al. (2021). Structural Insights into the Inhibition of Undecaprenyl Pyrophosphate Synthase from Gram-Positive Bacteria. Journal of Medicinal Chemistry 64(18) , 13540–13550. 10.1021/acs.jmedchem.1c00941. [PDB: 7jli] |
CMCF-ID |
Peer-Reviewed Article |
Health |