| Yu, C.; Drobnick, J.; Bryan, M.C.; Kiefer, J.; Lupardus, P.J. et al. (2019). Structure of the IRAK4 kinase domain with compound 5. Protein Data Bank: 6o9d. |
CMCF-ID |
PDB Deposition |
Health |
| Sack, J.S. (2019). Crystal structure of JAK3 kinase domain in complex with a pyrrolopyridazine carboxamide inhibitor. Protein Data Bank: 6ny4. |
CMCF-ID |
PDB Deposition |
Health |
| Spergel, Steven H.; Mertzman, Michael E.; Kempson, James; Guo, Junqing; Stachura, Sylwia et al. (2019). Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis. ACS Medicinal Chemistry Letters 10(3) , 306-311. 10.1021/acsmedchemlett.8b00508. [PDB: 6ny4] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Garside, E.L.; MacMillan, A.M. (2019). Prp8 RH domain from C. merolae. Protein Data Bank: 6nqi. |
CMCF-ID |
PDB Deposition |
Health |
| Garside, E.L.; Whelan, T.A.; Stark, M.R.; Rader, S.D.; Fast, N.M. et al. (2019). Prp8 in a Reduced Spliceosome Lacks a Conserved Toggle that Correlates with Splicing Complexity across Diverse Taxa. Journal of Molecular Biology 431(14) . 10.1016/j.jmb.2019.04.047. [PDB: 6nqi] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Fenalti, G. (2019). Crystal structure of the human TTK in complex with an inhibitor. Protein Data Bank: 6n6o. |
CMCF-ID |
PDB Deposition |
Health |
| Riggs, Jennifer R.; Elsner, Jan; Cashion, Dan; Robinson, Dale; Tehrani, Lida et al. (2019). Design and Optimization Leading to an Orally Active TTK Protein Kinase Inhibitor with Robust Single Agent Efficacy. Journal of Medicinal Chemistry 62(9) , 4401-4410. 10.1021/acs.jmedchem.8b01869. [PDB: 6n6o] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Caveney, N.A.; Strynadka, N.C.J. (2019). Crystal structure of GIL01 gp7. Protein Data Bank: 6n7o. |
CMCF-BM |
PDB Deposition |
Health |
| Caveney, Nathanael A.; Pavlin, Anja; Caballero, Guillermo; Bahun, Miha; Hodnik, Vesna et al. (2019). Structural Insights into Bacteriophage GIL01 gp7 Inhibition of Host LexA Repressor. Structure 27(7) . 10.1016/j.str.2019.03.019. [PDB: 6n7o] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Tamura, K.; Gardill, B.R.; Brumer, H.; Van Petegem, F. (2019). Bacteroides ovatus mixed-linkage glucan utilization locus (MLGUL) SGBP-B in complex with mixed-linkage heptasaccharide. Protein Data Bank: 6e9b. |
CMCF-BM |
PDB Deposition |
Health |
| Tamura, Kazune; Foley, Matthew H.; Gardill, Bernd R.; Dejean, Guillaume; Schnizlein, Matthew et al. (2019). Surface glycan-binding proteins are essential for cereal beta-glucan utilization by the human gut symbiont Bacteroides ovatus. Cellular and Molecular Life Sciences 76(21) . 10.1007/s00018-019-03115-3. [PDB: 6e9b] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Haji-Ghassemi, Omid; Yuchi, Zhiguang; Van Petegem, Filip (2019). The Cardiac Ryanodine Receptor Phosphorylation Hotspot Embraces PKA in a Phosphorylation-Dependent Manner. Molecular Cell 75(1) . 10.1016/j.molcel.2019.04.019. [PDB: 6mm6, 6mm7] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Halgas, O.; Zarabi, S.F.; Schimmer, A.; Pai, E.F. (2019). Human mitochondrial ClpP in complex with ONC201 (TIC10). Protein Data Bank: 6dl7. |
CMCF-ID |
PDB Deposition |
Health |
| Ishizawa, Jo; Zarabi, Sarah F.; Davis, R. Eric; Halgas, Ondrej; Nii, Takenobu et al. (2019). Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality. Cancer Cell 35(5) . 10.1016/j.ccell.2019.03.014. [PDB: 6dl7] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| van Petegem, F.; Haji-Ghassemi, O. (2019). Catalytic subunit of cAMP-dependent protein kinase A in complex with RyR2 K2879A, S2813D phosphomimetic (2699-2904) crystal form 1. Protein Data Bank: 6mm7. |
CMCF-BM |
PDB Deposition |
Health |