| Burke, J.E.; Rathinaswamy, M.K.; Harris, N.J. (2021). Gedatolisib bound to the PI3Kg catalytic subunit p110 gamma. Protein Data Bank: 7jwe. |
CMCF-ID |
PDB Deposition |
Health |
| Burke, J.E.; Rathinaswamy, M.K.; Harris, N.J. (2021). NVS-PI3-4 bound to the PI3Kg catalytic subunit p110 gamma. Protein Data Bank: 7jx0. |
CMCF-ID |
PDB Deposition |
Health |
| Burke, J.E.; Rathinaswamy, M.K.; Harris, N.J. (2021). IPI-549 bound to the PI3Kg catalytic subunit p110 gamma. Protein Data Bank: 7jwz. |
CMCF-ID |
PDB Deposition |
Health |
| Rathinaswamy, Manoj K; Gaieb, Zied; Fleming, Kaelin D; Borsari, Chiara; Harris, Noah J et al. (2021). Disease-related mutations in PI3Kγ disrupt regulatory C-terminal dynamics and reveal a path to selective inhibitors. eLife 10. 10.7554/elife.64691. [PDB: 7jwe, 7jwz, 7jx0] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Cygler, M.; Chung, I.Y.W. (2021). Structure of RavA (lpp0008) E38A/K39A surface entropy reduction mutant. Protein Data Bank: 6wo6. |
CMCF-ID |
PDB Deposition |
Health |
| Chung, Ivy Y. W.; Li, Lei; Tyurin, Oleg; Gagarinova, Alla; Wibawa, Raissa et al. (2021). Structural and functional study of
Legionella pneumophila
effector RavA. Protein Science 30(5) . 10.1002/pro.4057. [PDB: 6wo6] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Lin, C.S.; Chan, A.C.; Murphy, M.E. (2021). Crystal structure of the helical cell shape determining protein Pgp2 (K307A mutant) from Campylobacter jejuni. Protein Data Bank: 6xj7. |
CMCF-BM |
PDB Deposition |
Health |
| Lin, Chang Sheng-Huei; Chan, Anson C.K.; Vermeulen, Jenny; Brockerman, Jacob; Soni, Arvind S. et al. (2021). Peptidoglycan binding by a pocket on the accessory NTF2-domain of Pgp2 directs helical cell shape of Campylobacter jejuni. Journal of Biological Chemistry 296, 100528. 10.1016/j.jbc.2021.100528. [PDB: 6xj7] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Sintchak, M.; Lane, W.; Bump, N. (2021). Structure of SUMO1-ML786519 adduct bound to SAE. Protein Data Bank: 6xog. |
CMCF-ID |
PDB Deposition |
Health |
| Langston, Steven P.; Grossman, Stephen; England, Dylan; Afroze, Roushan; Bence, Neil et al. (2021). Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer. Journal of Medicinal Chemistry 64(5) . 10.1021/acs.jmedchem.0c01491. [PDB: 6xog, 6xoh] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Huang, Ji; Fraser, Marie E. (2021). Second distinct conformation of the phosphohistidine loop in succinyl-CoA synthetase. Acta Crystallographica Section D: Structural Biology 77(3) , 357-368. 10.1107/s2059798321000334. [PDB: 7jj0, 7jkr] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Chen, S.; Lu, M. (2021). Arsenic-bound p53 DNA-binding domain mutant R249S. Protein Data Bank: 7dhz. |
CMCF-ID |
PDB Deposition |
Health |
| Li, Hao; Helpard, Luke; Ekeroot, Jonas; Rohani, Seyed Alireza; Zhu, Ning et al. (2021). Three-dimensional tonotopic mapping of the human cochlea based on synchrotron radiation phase-contrast imaging. Scientific Reports 11(1) , 4437. 10.1038/s41598-021-83225-w. |
BMIT-ID |
Peer-Reviewed Article |
Health |
| Murray, J.M. (2021). BRD4-BD1 Compound6 (methyl 4-(3,5-difluoropyridin-2-yl)-10-methyl-7-((methylsulfonyl)methyl)-11-oxo-3,4,10,11-tetrahydro-1H-1,4,10-triazadibenzo[cd,f]azulene-6-carboxylate). Protein Data Bank: 7khl. |
CMCF-ID |
PDB Deposition |
Health |
| Dragovich, Peter S.; Pillow, Thomas H.; Blake, Robert A.; Sadowsky, Jack D.; Adaligil, Emel et al. (2021). Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy. Journal of Medicinal Chemistry 64(5) . 10.1021/acs.jmedchem.0c01846. [PDB: 7khl] |
CMCF-ID |
Peer-Reviewed Article |
Health |