Publication Beamlines Strategic Pillar
Vallée, Frédéric; Casás-Selves, Matias; Bubenik, Monica; Duplessis, Martin; Sow, Boubacar et al. (2025). Discovery of RP-1664: A First-in-Class Orally Bioavailable, Selective PLK4 Inhibitor. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.5c00529. [PDB: 9o63] CMCF-ID Health
Daneshamouz, Sana; Saadati, Shaghayegh; Zhu, Sishi; Kalugin, Denis; Shoker, Ahmed et al. (2025). Investigation on the Detoxification of Indoxyl Sulfate (IS) and Indole-3-Acetic Acid (IAA) Protein-Bound Uremic Toxins (PBUTs) Using Trametes versicolor Biocompatible Laccase: In Situ Synchrotron Imaging, Experimental and Computational Studies. Applied Biochemistry and Biotechnology . 10.1007/s12010-025-05235-y. BMIT-ID Health
Ye, Qilu; Eves, Robert; Vance, Tyler D. R.; Hansen, Thomas; Sage, Adam P. et al. (2025). Aeromonas hydrophila RTX adhesin has three ligand-binding domains that give the bacterium the potential to adhere to and aggregate a wide variety of cell types. mBio 16(5) . 10.1128/mbio.03158-24. [PDB: 9cse] CMCF-ID Health
Mundboth, Kiran (2025). Canadian Light Source – 20 Years of Discovery. Canadian Journal of Chemistry . 10.1139/cjc-2024-0278. BMIT, BXDS, CMCF, FAR-IR, HXMA, MID-IR, SM Health
Kinzel, Olaf; Goldberg, Steven D.; Cummings, Maxwell D.; Gege, Christian; Steeneck, Christoph et al. (2025). Identification of JNJ-61803534, a RORγt Inverse Agonist for the Treatment of Psoriasis. Journal of Medicinal Chemistry 68(8) , 8713-8728. 10.1021/acs.jmedchem.5c00390. [PDB: 9n9l] CMCF-ID Health
Goncalves, Monica M.; Uday, Adwaith B.; Forrester, Taylor J. B.; Currie, S. Quinn W.; Kim, Angelina S. et al. (2025). Mechanism of allosteric activation in human mitochondrial ClpP protease. Proceedings of the National Academy of Sciences of the United States of America 122(16) . 10.1073/pnas.2419881122. [PDB: 9dqk, 9dql] CMCF-ID Health
Lee, Eunjeong; Tran, Norman; Redzic, Jasmina S.; Singh, Harmanpreet; Alamillo, Lorena et al. (2025). Identifying and controlling inactive and active conformations of a serine protease. Science Advances 11(15) . 10.1126/sciadv.adu7447. [PDB: 9bsh, 9bsm] CMCF-BM Health
Nakhla, Mina C.; Comita, Janelle; Shapiro, Adam B.; Moussa, Samir H.; Chen, April et al. (2025). Small molecule inhibitors of mannan-binding lectin-associated serine Proteases-2 and-3. European Journal of Medicinal Chemistry 289, 117238. 10.1016/j.ejmech.2025.117238. [PDB: 9d17, 9d3y, 9d40, 9d4d] CMCF-ID Health
Walker, Morgan E.; Zhu, Wei; Peterson, Janine H.; Wang, Hao; Patteson, Jon et al. (2025). Antibacterial macrocyclic peptides reveal a distinct mode of BamA inhibition. Nature Communications 16(1) . 10.1038/s41467-025-58086-w. [PDB: 9cs0, 9cs1] CMCF-ID Health
Sankhe, Safiétou; Fofana, Fatoumata G.; Heiba, Walid; Ogunyemi, Oludare M.; Masisi, Kabo et al. (2025). BioStruct-Africa’s capacity building workshops as a model for advancing the emerging community of structural biologists in Africa. Communications Chemistry 8(1) . 10.1038/s42004-025-01519-w. CMCF Health
Ebrahimi, Sadollah; Singh, Sanjeet Kumar; Rhazaoui, Abdessamia; Letendart, Colin; Daigle, Jean-Christophe et al. (2025). Molecular Insights into the Structure and Dynamics of Protic Organic Ionic Plastic Crystal (OIPC) 1,7-Diazabicyclo[5.4.0]undec-7-ene ([DBUH])–bis(fluorosulfonyl)imide ([FSI]). Journal of Physical Chemistry B 129(19) , 4832-4843. 10.1021/acs.jpcb.5c00469. BXDS Materials
Fan, Xiaoxuan; Teng, Zhenyuan; Han, Lupeng; Shen, Yongjie; Wang, Xiyang et al. (2025). Boosted charge and proton transfer over ternary Co/Co3O4/CoB for electrochemical nitric oxide reduction to ammonia. Nature Communications 16(1) . 10.1038/s41467-025-60043-6. HXMA Materials
Li, Qian; Zhang, Yanfei; Guo, Xiaotian; Yang, Zhangbin; Wang, Yixuan et al. (2025). Nucleation and Growth Mechanisms of Micro/Nano Structural Manganese‐Trimesic Acid Coordinations for Aqueous Zinc‐Ion Batteries. Angewandte Chemie 64(31) . 10.1002/anie.202509741. SXRMB Materials
Yang, Zhucheng; Chen, Ziyi; Li, Bo; Zhang, Ruixuan; Cao, Yitao et al. (2025). Integrating Sulfido Ligands into Thiolate-Gold(I) Clusters via Competing Bonding. CCS Chemistry 7(4) , 1100-1111. 10.31635/ccschem.024.202404942. CLS-APS Materials
Lazar, Sorin; Tiemeijer, Peter; Schnohr, Claudia S.; Meledina, Maria; Patzig, Christian et al. (2025). Enabling electron-energy-loss spectroscopy at very high energy losses: An opportunity to obtain x-ray absorption spectroscopy–like information using an electron microscope. Physical Review Applied 23(5) . 10.1103/physrevapplied.23.054095. SXRMB Materials