Publication Beamlines Strategic Pillar
Patel, Ankoor; McBride, Jessica A.M.; Mark, Brian L. (2021). The endopeptidase of the maize-affecting Marafivirus type member maize rayado fino virus doubles as a deubiquitinase. Journal of Biological Chemistry 297(2) , 100957. 10.1016/j.jbc.2021.100957. CMCF Health
van Vliet, Vera J. E.; Huynh, Nhan; Palà, Judith; Patel, Ankoor; Singer, Alex et al. (2022). Ubiquitin variants potently inhibit SARS-CoV-2 PLpro and viral replication via a novel site distal to the protease active site. PLoS Pathogens 18(12) , e1011065. 10.1371/journal.ppat.1011065. CMCF Health
Grochulski, Pawel; Labiuk, Shaunivan (2021). Review of health research at the Canadian Light Source. Nuclear Instruments and Methods in Physics Research. Section B: Beam Interactions with Materials and Atoms 499, 70-76. 10.1016/j.nimb.2021.05.003. BIOXAS, BMIT, CMCF, MID-IR, SM, SXRMB, VESPERS Health
Kozlov, Guennadi; Funato, Yosuke; Chen, Yu Seby; Zhang, Zhidian; Illes, Katalin et al. (2020). PRL3 pseudophosphatase activity is necessary and sufficient to promote metastatic growth. Journal of Biological Chemistry 295(33) , 11682-11692. 10.1074/jbc.ra120.014464. CMCF Health
Eble, Johannes A.; McDougall, Matthew; Orriss, George L.; Niland, Stephan; Johanningmeier, Benjamin et al. (2017). Dramatic and concerted conformational changes enable rhodocetin to block α2β1 integrin selectively. PLoS Biology 15(7) , e2001492. 10.1371/journal.pbio.2001492. [PDB: 5thp] CMCF, CMCF-ID Health
Aljghami, Mazen E.; Morey, Trevor M.; Mabanglo, Mark F.; Meyrick, Jonathan J.; Thomas, Huw B. et al. (2026). Identification of substrates of the human mitochondrial ClpXP protease and its implications for Perrault syndrome. Nature Communications . 10.1038/s41467-026-77888-0. CMCF-BM Health
Sychantha, David; Chen, Xuefei; Koteva, Kalinka; Prehna, Gerd; Wright, Gerard D. et al. (2024). Targeting bacterial nickel transport with aspergillomarasmine A suppresses virulence-associated Ni-dependent enzymes. Nature Communications 15(1) . 10.1038/s41467-024-48232-1. CMCF-BM Health
Szabla, Robert; Li, Mingyi; Warner, Victoria; Song, Yifeng; Junop, Murray et al. (2024). DdrC, a unique DNA repair factor from D. radiodurans, senses and stabilizes DNA breaks through a novel lesion-recognition mechanism. Nucleic Acids Research 52(15) , 9282-9302. 10.1093/nar/gkae635. CMCF-BM, CMCF-ID Health
Dolgova, Natalia; Uhlemann, Eva-Maria E; Boniecki, Michal T; Vizeacoumar, Frederick S; Ara, Anjuman et al. (2024). MEMO1 binds iron and modulates iron homeostasis in cancer cells. eLife 13. 10.7554/elife.86354. CMCF-BM, CMCF-ID Health
Tran, Thi Thanh Quynh; Narayanan, Chitra; Loes, Andrea N.; Click, Timothy H.; Pham, N.T.Hang et al. (2024). Ancestral sequence reconstruction dissects structural and functional differences among eosinophil ribonucleases. Journal of Biological Chemistry 300(5) , 107280. 10.1016/j.jbc.2024.107280. CMCF-BM Health
Frigon, Léonie; Pascal, John M. (2025). Crystal structure and mutagenesis of a nucleic acid–binding BRCT domain in human PARP4. Journal of Biological Chemistry 301(6) , 110277. 10.1016/j.jbc.2025.110277. CMCF-BM Health
Chatterjee, Som; Poon, Raymond; Satishkumar, Nidhi; Mosimann, Wesley; Hayatnagarkar, Vedangi et al. (2026). Stk1 is required for BlaR1-mediated broad-spectrum β-lactam resistance in epidemic-causing strains of Staphylococcus aureus. Materials & Design . 10.21203/rs.3.rs-8331258/v1. [PDB: 9ymt] CMCF-BM Health
Merchant, Rohan R.; Chernyak, Natalia; Lopez, Jovan A.; Sharp, Phillip P.; Mandal, Mihir et al. (2026). N -Alkyl and N -Aryl Aminopyrazole Spirocarbamates: A Two-Pronged Lead Optimization Strategy to Identify Orally Bioavailable Plasma Kallikrein Inhibitors. ACS Medicinal Chemistry Letters 17(3) , 744-749. 10.1021/acsmedchemlett.6c00066. [PDB: 10qs] CMCF-BM Health
Vara, Brandon A.; Lim, Jongwon; Moure, Casey J.; Schneider, Sebastian E.; Yeung, Charles S. et al. (2026). Discovery and In Vivo Evaluation of Aryl Ether YAP1/TEAD Inhibitors for the Treatment of Hippo-Driven Malignancies. Journal of Medicinal Chemistry 69(4) , 4303-4316. 10.1021/acs.jmedchem.5c02997. [PDB: 9yk2] CMCF-BM Health
Pham, N. T. Hang; Paré, Alex; Létourneau, Myriam; Fortier, Marlène; Chatenet, David et al. (2026). Network‐based allosteric analysis of galectin‐7: Key residues dictate functional communication and stability. Protein Science 35(3) . 10.1002/pro.70502. [PDB: 7n4o, 7n6c, 7n96] CMCF-BM Health